Search Results - "Thompson, Michael A."

Three-dimensional, single-molecule fluorescence imaging beyond the diffraction limit by using a double-helix point spread function by Pavani, Sri Rama Prasanna, Thompson, Michael A, Biteen, Julie S, Lord, Samuel J, Liu, Na, Twieg, Robert J, Piestun, Rafael, Moerner, W.E

“…We demonstrate single-molecule fluorescence imaging beyond the optical diffraction limit in 3 dimensions with a wide-field microscope that exhibits a…”
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Effect of Nanoparticle Surface Charge at the Plasma Membrane and Beyond by Arvizo, Rochelle R, Miranda, Oscar R, Thompson, Michael A, Pabelick, Christina M, Bhattacharya, Resham, Robertson, J. David, Rotello, Vincent M, Prakash, Y. S, Mukherjee, Priyabrata

“…Herein, we demonstrate that the surface charge of gold nanoparticles (AuNPs) plays a critical role in modulating membrane potential of different malignant and…”
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Analytical Tools To Distinguish the Effects of Localization Error, Confinement, and Medium Elasticity on the Velocity Autocorrelation Function by Weber, Stephanie C., Thompson, Michael A., Moerner, W.E., Spakowitz, Andrew J., Theriot, Julie A.

“…Single particle tracking is a powerful technique for investigating the dynamic behavior of biological molecules. However, many of the analytical tools are…”
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Refining a Postpandemic Approach to Cancer Screening by Thompson, Michael A

“…In introducing Volume 8, Issue 4 of Journal of Patient-Centered Research and Reviews — a specially themed issue comprised of several works focused on improving…”
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Three-dimensional tracking of single mRNA particles in Saccharomyces cerevisiae using a double-helix point spread function by Thompson, Michael A., Casolari, Jason M., Badieirostami, Majid, Brown, Patrick O., Moerner, W. E.

“…Optical imaging of single biomolecules and complexes in living cells provides a useful window into cellular processes. However, the three-dimensional dynamics…”
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Brain-derived neurotrophic factor and airway fibrosis in asthma by Freeman, Michelle R, Sathish, Venkatachalem, Manlove, Logan, Wang, Shengyu, Britt, Jr, Rodney D, Thompson, Michael A, Pabelick, Christina M, Prakash, Y S

“…Airway remodeling in asthma driven by inflammation involves proliferation of epithelial cells and airway smooth muscle (ASM), as well as enhanced extracellular…”
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Super-Resolution Imaging of the Nucleoid-Associated Protein HU in Caulobacter crescentus by Lee, Steven F., Thompson, Michael A., Schwartz, Monica A., Shapiro, Lucy, Moerner, W.E.

“…Little is known about the structure and function of most nucleoid-associated proteins (NAPs) in bacteria. One reason for this is that the distribution and…”
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RNAi screening identifies a mechanosensitive ROCK-JAK2-STAT3 network central to myofibroblast activation by Oh, Raymond S, Haak, Andrew J, Smith, Karry M J, Ligresti, Giovanni, Choi, Kyoung Moo, Xie, Tiao, Wang, Shaohua, Walters, Paula R, Thompson, Michael A, Freeman, Michelle R, Manlove, Logan J, Chu, Vivian M, Feghali-Bostwick, Carol, Roden, Anja C, Schymeinsky, Jürgen, Pabelick, Christina M, Prakash, Y S, Vassallo, Robert, Tschumperlin, Daniel J

“…Myofibroblasts play key roles in wound healing and pathological fibrosis. Here, we used an RNAi screen to characterize myofibroblast regulatory genes, using a…”
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BDNF secretion by human pulmonary artery endothelial cells in response to hypoxia by Helan, Martin, Aravamudan, Bharathi, Hartman, William R, Thompson, Michael A, Johnson, Bruce D, Pabelick, Christina M, Prakash, Y.S

“…Abstract Within human pulmonary artery, neurotrophin growth factors [NTs; e.g. brain-derived neurotrophic factor (BDNF)] and their high-affinity receptors…”
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Addressing Administrative and Regulatory Burden in Cancer Clinical Trials: Summary of a Stakeholder Survey and Workshop Hosted by the American Society of Clinical Oncology and the Association of American Cancer Institutes by Vose, Julie M, Levit, Laura A, Hurley, Patricia, Lee, Carrie, Thompson, Michael A, Stewart, Teresa, Hofacker, Janie, Bruinooge, Suanna S, Hayes, Daniel F

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Mechanisms of Cigarette Smoke Effects on Human Airway Smooth Muscle by Wylam, Mark E, Sathish, Venkatachalem, VanOosten, Sarah Kay, Freeman, Michelle, Burkholder, David, Thompson, Michael A, Pabelick, Christina M, Prakash, Y S

“…Cigarette smoke contributes to or exacerbates airway diseases such as asthma and COPD, where airway hyperresponsiveness and airway smooth muscle (ASM)…”
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Investigating the Structure of Multicomponent Gel-Phase Lipid Bilayers by Hartkamp, Remco, Moore, Timothy C., Iacovella, Christopher R., Thompson, Michael A., Bulsara, Pallav A., Moore, David J., McCabe, Clare

“…Single- and multicomponent lipid bilayers of 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC), 1,2-distearoyl-sn-glycero-3-phosphatidylcholine (DSPC),…”
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Clinician survey regarding measurable residual disease-guided decision-making in multiple myeloma by Derman, Benjamin A., Jakubowiak, Andrzej J., Thompson, Michael A.

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Composition Dependence of Water Permeation Across Multicomponent Gel-Phase Bilayers by Hartkamp, Remco, Moore, Timothy C, Iacovella, Christopher R, Thompson, Michael A, Bulsara, Pallav A, Moore, David J, McCabe, Clare

“…The permeability of multicomponent phospholipid bilayers in the gel phase is investigated via molecular dynamics simulation. The physical role of the different…”
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Evidence of Systemic Th2-Driven Chronic Inflammation in Patients with Metastatic Melanoma by Nevala, Wendy K, Vachon, Celine M, Leontovich, Alexey A, Scott, Christopher G, Thompson, Michael A, Markovic, Svetomir N

“…Purpose: Immunotherapeutic modalities are commonly used for treatment of patients with melanoma. The therapeutic success in preclinical models has not yielded…”
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Thymic stromal lymphopoietin in cigarette smoke-exposed human airway smooth muscle by Smelter, Dan F, Sathish, Venkatachalem, Thompson, Michael A, Pabelick, Christina M, Vassallo, Robert, Prakash, Y S

“…Thymic stromal lymphopoietin (TSLP) is a newly identified IL-7-like cytokine known to be expressed in airway biopsies of patients with asthma and chronic…”
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Lithographically Patterned Nanowire Electrodeposition: A Method for Patterning Electrically Continuous Metal Nanowires on Dielectrics by Xiang, Chenxiang, Kung, Sheng-Chin, Taggart, David K, Yang, Fan, Thompson, Michael A, Güell, Aleix G, Yang, Yongan, Penner, Reginald M

“…Lithographically patterned nanowire electrodeposition (LPNE) is a new method for fabricating polycrystalline metal nanowires using electrodeposition. In LPNE,…”
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Rapid effects of estrogen on intracellular Ca2+ regulation in human airway smooth muscle by Townsend, Elizabeth A, Thompson, Michael A, Pabelick, Christina M, Prakash, Y S

“…The severity of asthma, a disease characterized by airway hyperresponsiveness and inflammation, is enhanced in some women during the menstrual cycle and during…”
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Caveolin-1 regulation of store-operated Ca2+ influx in human airway smooth muscle by SATHISH, Venkatachalem, ABCEJO, Amard J, THOMPSON, Michael A, SIECK, Gary C, PRAKASH, Y. S, PABELICK, Christina M

“…Caveolae, plasma membrane invaginations with constitutive caveolin proteins, harbour proteins involved in intracellular calcium ([Ca 2+ ] i ) regulation. In…”
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Brain-derived neurotrophic factor enhances calcium regulatory mechanisms in human airway smooth muscle by Abcejo, Amard J, Sathish, Venkatachalem, Smelter, Dan F, Aravamudan, Bharathi, Thompson, Michael A, Hartman, William R, Pabelick, Christina M, Prakash, Y S

“…Neurotrophins (NTs), which play an integral role in neuronal development and function, have been found in non-neuronal tissue (including lung), but their role…”
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