Search Results - "Thompson, Maximillian A."
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The SKN‐1/Nrf2 transcription factor can protect against oxidative stress and increase lifespan in C. elegans by distinct mechanisms
Published in Aging cell (01-10-2017)“…Summary In C. elegans, the skn‐1 gene encodes a transcription factor that resembles mammalian Nrf2 and activates a detoxification response. skn‐1 promotes…”
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Journal Article -
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Neuronal SKN-1B modulates nutritional signalling pathways and mitochondrial networks to control satiety
Published in PLoS genetics (04-03-2021)“…The feeling of hunger or satiety results from integration of the sensory nervous system with other physiological and metabolic cues. This regulates food…”
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Journal Article -
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Olfactory chemosensation extends lifespan through TGF-β signaling and UPR activation
Published in Nature aging (01-08-2023)“…Animals rely on chemosensory cues to survive in pathogen-rich environments. In Caenorhabditis elegans, pathogenic bacteria trigger aversive behaviors through…”
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Olfaction: an emerging regulator of longevity and metabolism
Published in Trends in cell biology (01-03-2024)“…Ageing is a malleable process influenced by the environment. Recent research reveals that neurons interact with peripheral organs to regulate metabolism and…”
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RNA polymerase III limits longevity downstream of TORC1
Published in Nature (London) (14-12-2017)“…RNA polymerase III is a key evolutionarily conserved regulator of longevity that may have potential as a therapeutic target for age-related conditions. Pol III…”
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The SKN-1/Nrf2 transcription factor can protect against oxidative stress and increase lifespan in C.ᅡ elegans by distinct mechanisms
Published in Aging cell (01-10-2017)“…Summary In C. elegans, the skn-1 gene encodes a transcription factor that resembles mammalian Nrf2 and activates a detoxification response. skn-1 promotes…”
Get full text
Journal Article