Search Results - "Thompson, Louisa"

Dissociating Statistically Determined Normal Cognitive Abilities and Mild Cognitive Impairment Subtypes with DCTclock by Matusz, Emily F, Price, Catherine C, Lamar, Melissa, Swenson, Rod, Au, Rhoda, Emrani, Sheina, Wasserman, Victor, Libon, David J, Thompson, Louisa I

“…To determine whether the DCTclock can detect differences across groups of patients seen in the memory clinic for suspected dementia. Patients ( = 123) were…”
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Developing retinal biomarkers for the earliest stages of Alzheimer's disease: What we know, what we don't, and how to move forward by Alber, Jessica, Goldfarb, Danielle, Thompson, Louisa I., Arthur, Edmund, Hernandez, Kimberly, Cheng, Derrick, DeBuc, Delia Cabrera, Cordeiro, Francesca, Provetti‐Cunha, Leonardo, den Haan, Jurre, Van Stavern, Gregory P., Salloway, Stephen P., Sinoff, Stuart, Snyder, Peter J.

“…The last decade has seen a substantial increase in research focused on the identification, development, and validation of diagnostic and prognostic retinal…”
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Post-synaptic Density-95 (PSD-95) Binding Capacity of G-protein-coupled Receptor 30 (GPR30), an Estrogen Receptor That Can Be Identified in Hippocampal Dendritic Spines by Akama, Keith T., Thompson, Louisa I., Milner, Teresa A., McEwen, Bruce S.

“…The estrogen 17β-estradiol (E2) modulates dendritic spine plasticity in the cornu ammonis 1 (CA1) region of the hippocampus, and GPR30 (G-protein coupled…”
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G-protein-coupled estrogen receptor 1 is anatomically positioned to modulate synaptic plasticity in the mouse hippocampus by Waters, Elizabeth M, Thompson, Louisa I, Patel, Parth, Gonzales, Andreina D, Ye, Hector Zhiyu, Filardo, Edward J, Clegg, Deborah J, Gorecka, Jolanta, Akama, Keith T, McEwen, Bruce S, Milner, Teresa A

“…Both estrous cycle and sex affect the numbers and types of neuronal and glial profiles containing the classical estrogen receptors α and β, and synaptic levels…”
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Comparing the accuracy of the DCTclock and Montreal Cognitive Assessment to detect cognitive impairment and cerebral amyloid status in older adults by Swaminathan, Aathman, Emrani, Sheina, Arthur, Edmund, Strenger, Jennifer, Salloway, Stephen P., Correia, Stephen, Thompson, Louisa I

“…Background Sensitive and non‐invasive methods of screening for early‐stage Alzheimer’s disease (AD) are urgently needed. Digital assessment tools have the…”
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APOE Genotype Disclosure Influences Decisions About Future Planning but not Adoption of Healthy Lifestyle Changes in Cognitively Unimpaired Individuals by Popescu, Dominique L., Lee, Athene K., Arthur, Edmund, Thompson, Louisa I., Alber, Jessica

“…Background Studies have shown apolipoprotein E (APOE) genotype disclosure to be safe and well-tolerated in cognitively unimpaired (CU) older adults. This study…”
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OCTA reveals remodeling of the peripheral capillary free zones in normal aging by Arthur, Edmund, Alber, Jessica, Thompson, Louisa I., Sinoff, Stuart, Snyder, Peter J.

“…The retinal neurovascular unit consists of blood vessel endothelial cells, pericytes, neurons, astrocytes, and Müller cells that form the inner retinal blood…”
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Depression screening in cognitively normal older adults: Measurement bias according to subjective memory decline, brain amyloid burden, cognitive function, and sex by Thompson, Louisa I., Jones, Richard N.

“…Introduction Understanding the associations among depression, subjective cognitive decline, and prodromal Alzheimer's disease (AD) has important implications…”
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A highly feasible, reliable, and fully remote protocol for mobile app‐based cognitive assessment in cognitively healthy older adults by Thompson, Louisa I., Harrington, Karra D., Roque, Nelson, Strenger, Jennifer, Correia, Stephen, Jones, Richard N., Salloway, Stephen, Sliwinski, Martin J.

“…Introduction The early detection of cognitive impairment is one of the most important challenges in Alzheimer's disease (AD) research. The use of brief,…”
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Expression of homologous RND efflux pump genes is dependent upon AcrB expression: implications for efflux and virulence inhibitor design by Blair, Jessica M A, Smith, Helen E, Ricci, Vito, Lawler, Amelia J, Thompson, Louisa J, Piddock, Laura J V

“…Enterobacteriaceae have multiple efflux pumps that confer intrinsic resistance to antibiotics. AcrB mediates clinically relevant multidrug resistance and is…”
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Safety and Tolerability of APOE Genotyping and Disclosure in Cognitively Normal Volunteers From the Butler Alzheimer’s Prevention Registry by Alber, Jessica, Popescu, Dominique, Thompson, Louisa I., Tonini, Gina-Marie, Arthur, Edmund, Oh, Hwamee, Correia, Stephen, Salloway, Stephen P., Lee, Athene K.

“…Aims: Alzheimer’s disease (AD) is a gradually progressive neurodegenerative disease that ultimately results in total loss of cognitive and functional…”
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The impact of APOE genotype disclosure on lifestyle behaviors and decisions about future directives by Popescu, Dominique L, Alber, Jessica, Thompson, Louisa I, Arthur, Edmund, Oh, Hwamee, Correia, Stephen, Salloway, Stephen P., Lee, Athene KW

“…Background Studies have shown apolipoprotein E (APOE) genotype disclosure to be safe and well tolerated in cognitively unimpaired (CU) older adults. Genotyping…”
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Disruption of cholinergic neurotransmission, within a cognitive challenge paradigm, is indicative of Aβ-related cognitive impairment in preclinical Alzheimer's disease after a 27-month delay interval by Alber, Jessica, Maruff, Paul, Santos, Cláudia Y, Ott, Brian R, Salloway, Stephen P, Yoo, Don C, Noto, Richard B, Thompson, Louisa I, Goldfarb, Danielle, Arthur, Edmund, Song, Alex, Snyder, Peter J

“…Abnormal beta-amyloid (Aβ) is associated with deleterious changes in central cholinergic tone in the very early stages of Alzheimer's disease (AD), which may…”
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A Potential Association Between Retinal Changes, Subjective Memory Impairment, and Anxiety in Older Adults at Risk for Alzheimer's Disease: A 27-Month Pilot Study by Cheng, Derrick L, Thompson, Louisa, Snyder, Peter J

“…The utility of subjective memory impairment (SMI) as a risk marker for preclinical Alzheimer's disease (AD) remains unclear; however, recent studies have…”
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Distribution of estrogen receptor beta containing cells in the brains of bacterial artificial chromosome transgenic mice by Milner, Teresa A, Thompson, Louisa I, Wang, Gang, Kievits, Justin A, Martin, Eugene, Zhou, Ping, McEwen, Bruce S, Pfaff, Donald W, Waters, Elizabeth M

“…Abstract In the brain, estrogen receptor β (ERβ) plays important roles in autonomic functions, stress reactivity and learning and memory processes. However,…”
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Remote and in‐clinic digital cognitive screening tools outperform the MoCA to distinguish cerebral amyloid status among cognitively healthy older adults by Thompson, Louisa I., Kunicki, Zachary J., Emrani, Sheina, Strenger, Jennifer, De Vito, Alyssa N., Britton, Karysa J., Dion, Catherine, Harrington, Karra D., Roque, Nelson, Salloway, Stephen, Sliwinski, Martin J., Correia, Stephen, Jones, Richard N.

“…INTRODUCTION We evaluated the accuracy of remote and in‐person digital tests to distinguish between older adults with and without AD pathological change and…”
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Affective differences in Iowa Gambling Task performance associated with sexual risk taking and substance use among HIV-positive and HIV-negative men who have sex with men by Golub, Sarit A., Thompson, Louisa I., Kowalczyk, William J.

“…We investigated the relationship between emotional distress and decision making in sexual risk and substance use behavior among 174 (ages 25 to 50 years, 53%…”
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Profiles of Executive Functioning: Associations With Substance Dependence and Risky Sexual Behavior by GOLUB, Sarit A, STARKS, Tyrel J, KOWALCZYK, William J, THOMPSON, Louisa I, PARSONS, Jeffrey T

“…The present investigations applied a theoretical perspective regarding the impact of executive functioning (EF) on sexual risk among substance users, using a…”
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Daratumumab (anti-CD38) induces loss of CD38 on red blood cells by Sullivan, Harold C., Gerner-Smidt, Christian, Nooka, Ajay K., Arthur, Connie M., Thompson, Louisa, Mener, Amanda, Patel, Seema R., Yee, Marianne, Fasano, Ross M., Josephson, Cassandra D., Kaufman, Richard M., Roback, John D., Lonial, Sagar, Stowell, Sean R.

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Digital phenotyping: An equal opportunity approach to reducing disparities in Alzheimer's disease and related dementia research by Britton, Gabrielle B., Huang, Li‐Kai, Villarreal, Alcibiades E., Levey, Allan, Philippakis, Anthony, Hu, Chaur‐Jong, Yang, Cheng Chang, Mushi, Declare, Oviedo, Diana C., Rangel, Giselle, Ho, Jor Sam, Thompson, Louisa, Khemakhem, Mahdi, Ross, Makayla, Carreira, María B., Kim, Nicole, Joung, Philip, Albastaki, Omar, Kuo, Po Chih, Low, Spencer, Paddick, Stella‐Maria, Kuan, Yi‐Chun, Au, Rhoda

“…A rapidly aging world population is fueling a concomitant increase in Alzheimer's disease (AD) and related dementias (ADRD). Scientific inquiry, however, has…”
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