Search Results - "Thompson, Kyle J"

Role of fatty acid binding proteins (FABPs) in cancer development and progression by McKillop, Iain H., Girardi, Cara A., Thompson, Kyle J.

“…Fatty acid binding proteins (FABPs) are small, water soluble proteins that bind long chain fatty acids and other biologically active ligands to facilitate…”
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Altered fatty acid‐binding protein 4 (FABP4) expression and function in human and animal models of hepatocellular carcinoma by Thompson, Kyle J., Austin, Rebecca Garland, Nazari, Shayan S., Gersin, Keith S., Iannitti, David A., McKillop, Iain H.

“…Background and Aims Hepatocellular carcinoma (HCC) is the third leading cause of cancer‐related mortality. Risk factors for developing HCC include viral…”
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Role of AMPK-SREBP Signaling in Regulating Fatty Acid Binding-4 (FABP4) Expression following Ethanol Metabolism by Attal, Neha, Marrero, Emilio, Thompson, Kyle J, McKillop, Iain H

“…Fatty acid binding protein-4 ( ) is not normally expressed in the liver but is induced in alcohol-dependent liver disease (ALD)). This study sought to identify…”
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The treatment sequence may matter in patients undergoing pancreatoduodenectomy for early stage pancreatic cancer in the era of modern chemotherapy by Watson, Michael D., Thompson, Kyle J., Musselwhite, Laura W., Hwang, Jimmy J., Baker, Erin H., Martinie, John B., Vrochides, Dionisios, Iannitti, David A., Ocuin, Lee M.

“…The aim of this study was to investigate outcomes associated with neoadjuvant chemotherapy in patients undergoing pancreatoduodenectomy for early stage…”
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Fatty acid binding protein-4 promotes alcohol-dependent hepatosteatosis and hepatocellular carcinoma progression by Attal, Neha, Sullivan, Mariel T., Girardi, Cara A., Thompson, Kyle J., McKillop, Iain H.

“…•Fatty liver disease (hepatosteatosis) is a hallmark of ALD and NAFLD.•FABP4 is normally expressed in adipocytes and macrophages.•ALD leads to FABP4…”
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Improved oncologic outcomes for minimally invasive left pancreatectomy: Propensity‐score matched analysis of the National Cancer Database by Watson, Michael D., Baimas‐George, Maria R., Thompson, Kyle J., Iannitti, David A., Ocuin, Lee M., Baker, Erin H., Martinie, John B., Vrochides, Dionisios

“…Background and objectives Minimally invasive (MIS) left pancreatectomy (LP) is increasingly used to treat pancreatic adenocarcinoma (PDAC). Despite improved…”
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Diet-Induced Obesity Enhances Progression of Hepatocellular Carcinoma through Tenascin-C/Toll-Like Receptor 4 Signaling by Benbow, Jennifer H, Thompson, Kyle J, Cope, Heidi L, Brandon-Warner, Elizabeth, Culberson, Catherine R, Bossi, Krista L, Li, Ting, Russo, Mark W, Gersin, Keith S, McKillop, Iain H, deLemos, Andrew S, Schrum, Laura W

“…Obesity is an independent risk factor for the development of liver fibrosis/cirrhosis and hepatocellular carcinoma (HCC). Tenascin-C (TnC), an extracellular…”
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The effect of alcohol on Sirt1 expression and function in animal and human models of hepatocellular carcinoma (HCC) by Thompson, Kyle J, Humphries, John R, Niemeyer, David J, Sindram, David, McKillop, Iain H

“…Chronic heavy alcohol use is an independent risk factor for developing hepatocellular carcinoma (HCC). Sirtuin-1 (Sirt1) is a NAD+-dependent deacetylase…”
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Targeting collagen expression in alcoholic liver disease by Thompson, Kyle J, McKillop, Iain H, Schrum, Laura W

“…Alcoholic liver disease （ALD） is a leading cause of liver disease and liver-related deaths globally, particularly in developed nations. Liver fibrosis is a…”
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Alcoholic and non-alcoholic steatohepatitis by Neuman, Manuela G., French, Samuel W., French, Barbara A., Seitz, Helmut K., Cohen, Lawrence B., Mueller, Sebastian, Osna, Natalia A., Kharbanda, Kusum K., Seth, Devanshi, Bautista, Abraham, Thompson, Kyle J., McKillop, Iain H., Kirpich, Irina A., McClain, Craig J., Bataller, Ramon, Nanau, Radu M., Voiculescu, Mihai, Opris, Mihai, Shen, Hong, Tillman, Brittany, Li, Jun, Liu, Hui, Thomes, Paul G., Ganesan, Murali, Malnick, Steve

“…This paper is based upon the “Charles Lieber Satellite Symposia” organized by Manuela G. Neuman at the Research Society on Alcoholism (RSA) Annual Meetings,…”
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Alcoholic liver disease: Clinical and translational research by Neuman, Manuela G., Malnick, Stephen, Maor, Yaakov, Nanau, Radu M., Melzer, Ehud, Ferenci, Peter, Seitz, Helmut K., Mueller, Sebastian, Mell, Haim, Samuel, Didier, Cohen, Lawrence B., Kharbanda, Kusum K., Osna, Natalia A., Ganesan, Murali, Thompson, Kyle J., McKillop, Iain H., Bautista, Abraham, Bataller, Ramon, French, Samuel W.

“…The present review spans a broad spectrum of topics dealing with alcoholic liver disease (ALD), including clinical research, translational research,…”
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Lysophosphatidic acid receptor expression and function in human hepatocellular carcinoma by Sokolov, Eugene, PhD, Eheim, Ashley L., PhD, Ahrens, William A., MD, Walling, Tracy L., BS, Swet, Jacob H., MS, McMillan, Matthew T., BA, Simo, Kerri A., MD, Thompson, Kyle J., PhD, Sindram, David, MD, PhD, McKillop, Iain H., PhD

“…Abstract Background Lysophosphatidic acid (LPA) is a ubiquitously expressed phospholipid that regulates diverse cellular functions. Previously identified LPA…”
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Role of alcohol in the development and progression of hepatocellular carcinoma by McKillop, Iain H, Schrum, Laura W, Thompson, Kyle J

“…Hepatocellular carcinoma (HCC) is a significant cause of cancer-related morbidity and mortality. Chronic, heavy ethanol consumption is a major risk for…”
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Cytochrome P450 2E1‐dependent hepatic ethanol metabolism induces fatty acid‐binding protein 4 and steatosis by Attal, Neha, Marrero, Emilio, Thompson, Kyle J., McKillop, Iain H.

“…Background Hepatic steatosis is an early pathology of alcohol‐associated liver disease (ALD). Fatty acid‐binding protein‐4 (FABP4, a FABP not normally produced…”
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Outcomes of adolescents compared with young adults after bariatric surgery: an analysis of 227,671 patients using the MBSAQIP data registry by Poliakin, Lauren, Roberts, Amanda, Thompson, Kyle J., Raheem, Enayetur, McKillop, Iain H., Nimeri, Abdelrahman

“…Obesity in the United States is increasingly prevalent in adolescents. Metabolic and bariatric surgery is offered at select sites to adolescents (<18 yr)…”
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Metabolic and Bariatric Surgery Outcomes in African American Patients: a Single Institution Experience by Wang, Alice, Abdurakhmanov, Alexander, Thompson, Kyle J., McKillop, Iain H., Vijayanagar, Vilok, Kuwada, Timothy S., Bauman, Roc, Barbat, Selwan, Gersin, Keith S., Nimeri, Abdelrahman

“…Background The incidence of obesity in African Americans (AAs) is higher than in non-AA in the USA. Previous studies using large national databases report that…”
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Examining the Hispanic paradox in bariatric surgery by Sundaresan, Naresh, Roberts, Amanda, Thompson, Kyle J., McKillop, Iain H., Barbat, Selwan, Nimeri, Abdelrahman

“…The obesity rate for the Hispanic population is significantly higher than that of white, non-Hispanic people in the United States, yet Hispanic people undergo…”
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Improved Flexible Coaxial Ribbon Cable for High-Density Superconducting Arrays by Smith, Jennifer Pearl, Mazin, Benjamin A., Boaventura, Alirio, Thompson, Kyle J., Daal, Miguel

“…Superconducting arrays often require specialized, high-density cryogenic cabling capable of transporting electrical signals across temperature stages with…”
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The role of total alimentary limb length in Roux-en-Y gastric bypass: a systematic review by Wang, Alice, Poliakin, Lauren, Sundaresan, Naresh, Vijayanagar, Vilok, Abdurakhmanov, Alexander, Thompson, Kyle J., Mckillop, Iain H., Barbat, Selwan, Bauman, Roc, Gersin, Keith S., Kuwada, Timothy S., Nimeri, Abdelrahman

“…Roux-en-Y gastric bypass (RYGB) is an established surgical treatment for obesity. Variations in limb length during RYGB procedures have been investigated for…”
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Ectodysplasin-A mRNA in exosomes released from activated hepatic stellate cells stimulates macrophage response by Marrero, Emilio, Attal, Neha, Nimeri, Ali, McGee, Rachel M., Benbow, Jennifer H., Thompson, Kyle J., Schrum, Laura W., McKillop, Iain H.

“…The interaction between activated hepatic stellate cells (aHSCs) and macrophages is central to liver fibrosis development. The cargo contained within aHSC…”
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