Search Results - "Thompson, Joyce J"

Extensive co-binding and rapid redistribution of NANOG and GATA6 during emergence of divergent lineages by Thompson, Joyce J., Lee, Daniel J., Mitra, Apratim, Frail, Sarah, Dale, Ryan K., Rocha, Pedro P.

“…Fate-determining transcription factors (TFs) can promote lineage-restricted transcriptional programs from common progenitor states. The inner cell mass (ICM)…”
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Distinctive epigenomes characterize glioma stem cells and their response to differentiation cues by Zhou, Dan, Alver, Bonnie M, Li, Shuang, Hlady, Ryan A, Thompson, Joyce J, Schroeder, Mark A, Lee, Jeong-Heon, Qiu, Jingxin, Schwartz, Philip H, Sarkaria, Jann N, Robertson, Keith D

“…Glioma stem cells (GSCs) are a subpopulation of stem-like cells that contribute to glioblastoma (GBM) aggressiveness, recurrence, and resistance to radiation…”
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Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells by Putiri, Emily L, Tiedemann, Rochelle L, Thompson, Joyce J, Liu, Chunsheng, Ho, Thai, Choi, Jeong-Hyeon, Robertson, Keith D

“…The TET family of dioxygenases catalyze conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), but their involvement in establishing normal…”
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An epigenome atlas of neural progenitors within the embryonic mouse forebrain by Rhodes, Christopher T., Thompson, Joyce J., Mitra, Apratim, Asokumar, Dhanya, Lee, Dongjin R., Lee, Daniel J., Zhang, Yajun, Jason, Eva, Dale, Ryan K., Rocha, Pedro P., Petros, Timothy J.

“…A comprehensive characterization of epigenomic organization in the embryonic mouse forebrain will enhance our understanding of neurodevelopment and provide…”
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Linkage-specific deubiquitylation by OTUD5 defines an embryonic pathway intolerant to genomic variation by Beck, David B, Basar, Mohammed A, Asmar, Anthony J, Thompson, Joyce J, Oda, Hirotsugu, Uehara, Daniela T, Saida, Ken, Pajusalu, Sander, Talvik, Inga, D'Souza, Precilla, Bodurtha, Joann, Mu, Weiyi, Barañano, Kristin W, Miyake, Noriko, Wang, Raymond, Kempers, Marlies, Tamada, Tomoko, Nishimura, Yutaka, Okada, Satoshi, Kosho, Tomoki, Dale, Ryan, Mitra, Apratim, Macnamara, Ellen, Matsumoto, Naomichi, Inazawa, Johji, Walkiewicz, Magdalena, Õunap, Katrin, Tifft, Cynthia J, Aksentijevich, Ivona, Kastner, Daniel L, Rocha, Pedro P, Werner, Achim

“…Reversible modification of proteins with linkage-specific ubiquitin chains is critical for intracellular signaling. Information on physiological roles and…”
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Integrating the Epigenome to Identify Drivers of Hepatocellular Carcinoma by Hlady, Ryan A., Sathyanarayan, Aishwarya, Thompson, Joyce J., Zhou, Dan, Wu, Qunfeng, Pham, Kien, Lee, Jeong‐Heon, Liu, Chen, Robertson, Keith D.

“…Disruption of epigenetic mechanisms has been intimately linked to the etiology of human cancer. Understanding how these epigenetic mechanisms (including DNA…”
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ZBTB24 is a transcriptional regulator that coordinates with DNMT3B to control DNA methylation by Thompson, Joyce J, Kaur, Rupinder, Sosa, Carlos P, Lee, Jeong-Heon, Kashiwagi, Katsunobu, Zhou, Dan, Robertson, Keith D

“…Abstract The interplay between transcription factors and epigenetic writers like the DNA methyltransferases (DNMTs), and the role of this interplay in gene…”
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MLL3/MLL4 methyltransferase activities control early embryonic development and embryonic stem cell differentiation in a lineage-selective manner by Xie, Guojia, Lee, Ji-Eun, Senft, Anna D., Park, Young-Kwon, Jang, Younghoon, Chakraborty, Shreeta, Thompson, Joyce J., McKernan, Kaitlin, Liu, Chengyu, Macfarlan, Todd S., Rocha, Pedro P., Peng, Weiqun, Ge, Kai

“…H3K4me1 methyltransferases MLL3 (KMT2C) and MLL4 (KMT2D) are critical for enhancer activation, cell differentiation and development. However, roles of MLL3/4…”
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Understanding the Role of a Zinc-Finger Protein, ZBTB24, in Shaping the Epigenome by Thompson, Joyce J

“…Epigenetics mechanisms involving DNA and histones, through their influence on chromatin structure, regulate several biological outcomes including…”
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