Search Results - "Thompson, Jerry"
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1
The Service Entrance
Published in Raritan (01-12-2021)“…Bags of cement or other construction materials going in, or buckets or metal containers of demolished plaster and other debris going out, may sit there,…”
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Differential Activation of Nuclear Receptors by Perfluorinated Fatty Acid Analogs and Natural Fatty Acids: A Comparison of Human, Mouse, and Rat Peroxisome Proliferator-Activated Receptor-α, -β, and -γ, Liver X Receptor-β, and Retinoid X Receptor-α
Published in Toxicological sciences (01-08-2006)“…Administration of ammonium salts of perfluorooctanoate (PFOA) to rats results in peroxisome proliferation and benign liver tumors, events associated with…”
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3
Diagnosing mucopolysaccharidosis IVA
Published in Journal of inherited metabolic disease (01-03-2013)“…Mucopolysaccharidosis IVA (MPS IVA; Morquio A syndrome) is an autosomal recessive lysosomal storage disorder resulting from a deficiency of…”
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4
Evidence for triclosan-induced activation of human and rodent xenobiotic nuclear receptors
Published in Toxicology in vitro (01-10-2013)“…•TCS may decrease serum thyroxine via transcriptional up-regulation of catabolism.•We tested this hypothesis using human, rat, and mouse CAR and PXR reporter…”
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Interleukin-2 suppression by 2-arachidonyl glycerol is mediated through peroxisome proliferator-activated receptor gamma independently of cannabinoid receptors 1 and 2
Published in Molecular pharmacology (01-07-2006)“…2-Arachidonyl glycerol (2-AG) is an endogenous arachidonic acid derivative that binds cannabinoid receptors CB1 and CB2 and is hence termed an endocannabinoid…”
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6
Regulation of inflammatory and lipid metabolism genes by eicosapentaenoic acid-rich oil[S]
Published in Journal of lipid research (01-08-2012)“…Omega-3-PUFAs, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), are associated with prevention of various aspects of metabolic syndrome. In the…”
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Walnut oil increases cholesterol efflux through inhibition of stearoyl CoA desaturase 1 in THP-1 macrophage-derived foam cells
Published in Nutrition & metabolism (26-08-2011)“…Walnuts significantly decrease total and low-density lipoprotein cholesterol in normo- and hypercholesterolemic individuals. No study to date has evaluated the…”
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Alpha-linolenic acid increases cholesterol efflux in macrophage-derived foam cells by decreasing stearoyl CoA desaturase 1 expression: evidence for a farnesoid-X-receptor mechanism of action
Published in The Journal of nutritional biochemistry (01-04-2012)“…Increased cholesterol efflux from macrophage-derived foam cells (MDFCs) is an important protective mechanism to decrease lipid load in the atherosclerotic…”
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9E,11E-conjugated linoleic acid increases expression of the endogenous antiinflammatory factor, interleukin-1 receptor antagonist, in RAW 264.7 cells
Published in The Journal of nutrition (01-10-2009)“…Despite having a similar structure, various conjugated linoleic acid (CLA) isomers have a distinct gene expression pattern in RAW 264.7 (RAW) cells, a mouse…”
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10
Enzyme-Replacement Therapy in Mucopolysaccharidosis I
Published in The New England journal of medicine (18-01-2001)“…Mucopolysaccharidosis I is a lysosomal storage disease caused by a deficiency of α-L-iduronidase, an enzyme that cleaves the terminal α-l-idu-ronic acid…”
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Activation of Mouse and Human Peroxisome Proliferator-Activated Receptors (PPARs) by Phthalate Monoesters
Published in Toxicological sciences (01-11-2004)“…Administration of phthalates is known to cause toxicity and liver cancer in rodents through the activation of peroxisome proliferator-activated receptors…”
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The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator-activated receptor-β/δ (PPARβ/δ)
Published in Free radical biology & medicine (15-04-2007)“…Liver insufficiency and damage are major causes of death and disease worldwide and may result from exposure to environmental toxicants, specific combinations…”
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13
New Substrates and Enzyme Assays for the Detection of Mucopolysaccharidosis III (Sanfilippo Syndrome) Types A, B, C, and D by Tandem Mass Spectrometry
Published in Bioconjugate chemistry (21-03-2012)“…The clinical phenotype of Sanfilippo Syndrome is caused by one of four enzyme deficiencies that are associated with a defect in mucopolysaccharide metabolism…”
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Mechanistic Examination of Walnuts in Prevention of Breast Cancer
Published in Nutrition and cancer (01-10-2012)“…Walnuts contain bioactive molecules that may contribute to their beneficial effects, including alpha-linolenic acid (ALA) and phytosterols. In these studies,…”
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Dasatinib inhibits both osteoclast activation and prostate cancer PC-3 cell-induced osteoclast formation
Published in Cancer biology & therapy (15-11-2009)“…Purpose: Therapies to target prostate cancer bone metastases have only limited effects. New treatments are focused on the interaction between cancer cells,…”
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Effects of cranberry extracts on gene expression in THP‐1 cells
Published in Food science & nutrition (01-01-2017)“…Cranberry contains high levels of nutrients and bioactive molecules that have health‐promoting properties. The purpose of the present studies was to determine…”
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Differential nucleobase protection against 5-fluorouracil toxicity for squamous and columnar cells: implication for tissue function and oncogenesis
Published in Investigational new drugs (01-10-2015)“…Summary Purpose The goal of these studies was to test if local excess of a normal nucleobase substrate prevents the toxicity of protracted 5FU exposure used in…”
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10E12Z CLA alters adipocyte differentiation and adipocyte cytokine expression and induces macrophage proliferation
Published in The Journal of nutritional biochemistry (01-05-2012)“…The trans-10, cis-12 (10e12z) conjugated linoleic acid (CLA) isomer of CLA is responsible for loss of lipid storage or adipose tissue in vitro or in vivo. This…”
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Role of Peroxisome Proliferator-Activated Receptor β/δ and B-Cell Lymphoma-6 in Regulation of Genes Involved in Metastasis and Migration in Pancreatic Cancer Cells
Published in PPAR Research (01-01-2013)“…PPARβ/δ is a ligand-activated transcription factor that regulates various cellular functions via induction of target genes directly or in concert with its…”
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Isomer-specific effects of conjugated linoleic acid on gene expression in RAW 264.7
Published in The Journal of nutritional biochemistry (01-11-2009)“…Conjugated linoleic acid (CLA) is a mixture of dietary fatty acids that has various beneficial effects including decreasing cancer, atherosclerosis, diabetes…”
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