Search Results - "Thompson, Heather L"
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Functional and Homeostatic Impact of Age-Related Changes in Lymph Node Stroma
Published in Frontiers in immunology (14-06-2017)“…Adults over 65 years of age are more vulnerable to infectious disease and show poor responses to vaccination relative to those under 50. A complex set of…”
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Mouse TU tagging: a chemical/genetic intersectional method for purifying cell type-specific nascent RNA
Published in Genes & development (01-01-2013)“…Transcriptional profiling is a powerful approach for understanding development and disease. Current cell type-specific RNA purification methods have…”
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Defective Transcriptional Programming of Effector CD8 T Cells in Aged Mice Is Cell-Extrinsic and Can Be Corrected by Administration of IL-12 and IL-18
Published in Frontiers in immunology (18-09-2019)“…In response to infection with intracellular microorganisms, old mice mobilize decreased numbers of antigen-specific CD8 T cells with reduced expression of…”
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F4/80+ Host Macrophages Are a Barrier to Murine Embryonic Stem Cell-Derived Hematopoietic Progenitor Engraftment In Vivo
Published in Journal of immunology research (01-01-2016)“…Understanding how embryonic stem cells and their derivatives interact with the adult host immune system is critical to developing their therapeutic potential…”
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Evaluation of phonological processing skills of young children with neurofibromatosis type 1
Published in Developmental medicine and child neurology (01-07-2018)“…This commentary is on the original article by Arnold et al. on pages 703–710 of this issue…”
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Prevalence of Bullying in California Youth with Disabilities
Published in International Journal of Bullying Prevention (01-09-2024)“…Youth with disabilities experience bullying at rates much higher than those who do not identify as having a disability; however, they are often…”
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Distinct Effector Mechanisms in the Development of Autoimmune Neuropathy versus Diabetes in Nonobese Diabetic Mice
Published in The Journal of immunology (1950) (01-11-2005)“…NOD mice deficient for the costimulatory molecule B7-2 (NOD-B7-2KO mice) are protected from autoimmune diabetes but develop a spontaneous autoimmune peripheral…”
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Psycholinguistic Profiling Differentiates Specific Language Impairment from Typical Development and from Attention-Deficit/Hyperactivity Disorder
Published in Journal of speech, language, and hearing research (01-02-2011)“…Purpose: Practitioners must have confidence in the capacity of their language measures to discriminate developmental language disorders from typical…”
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Patient Report of Hearing in Neurofibromatosis Type 2: Recommendations for Clinical Trials
Published in Neurology (17-08-2021)“…To systematically evaluate published patient-reported outcome measures for the assessment of hearing function and hearing-related quality of life (QoL) and…”
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Patient-reported measures of tinnitus for individuals with neurofibromatosis type 2–related schwannomatosis: Recommendations for clinical trials
Published in Clinical trials (London, England) (01-02-2024)“…Background Neurofibromatosis type 2–related schwannomatosis is a genetic disease characterized by the development of bilateral vestibular schwannomas,…”
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Role of Cell-Intrinsic and Environmental Age-Related Changes in Altered Maintenance of Murine T Cells in Lymphoid Organs
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (09-07-2018)“…Age-related changes in primary lymphoid organs are well described. Less is known about age-related changes affecting peripheral lymphoid organs, although…”
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Lymph nodes as barriers to T‐cell rejuvenation in aging mice and nonhuman primates
Published in Aging cell (01-02-2019)“…In youth, thymic involution curtails production of new naïve T cells, placing the onus of T‐cell maintenance upon secondary lymphoid organs (SLO). This…”
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Current Recommendations for Patient-Reported Outcome Measures Assessing Domains of Quality of Life in Neurofibromatosis Clinical Trials
Published in Neurology (17-08-2021)“…To review and recommend patient-reported outcome (PRO) measures assessing multidimensional domains of quality of life (QoL) to use as clinical endpoints in…”
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Recommendations for Social Skills End Points for Clinical Trials in Neurofibromatosis Type 1
Published in Neurology (17-08-2021)“…To review parent-report social skills measures to identify and recommend consensus outcomes for use in clinical trials of social deficit in children and…”
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Recommendations for Measurement of Attention Outcomes in Preschoolers With Neurofibromatosis
Published in Neurology (17-08-2021)“…Children with neurofibromatosis type 1 (NF1) are at increased risk for attention problems. While most research has been conducted with school-aged cohorts,…”
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Recommendations for assessing appearance concerns related to plexiform and cutaneous neurofibromas in neurofibromatosis 1 clinical trials
Published in Clinical trials (London, England) (01-02-2024)“…Background/Aims Individuals with neurofibromatosis 1 may experience changes in their appearance due to physical manifestations of the disorders and/or…”
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Modelling the impact of urbanisation on regional climate in the Greater London Area
Published in International journal of climatology (01-08-2013)“…Urban areas have well‐documented effects on climate, such as the urban heat island (UHI) effect, reduction of wind speeds, enhanced turbulence and boundary…”
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Preliminary Study of a Caregiver‐based Infant and Child Feeding and Swallowing Screening Tool
Published in Journal of pediatric gastroenterology and nutrition (01-06-2017)“…ABSTRACT Objectives: The Infant and Child Feeding Questionnaire (ICFQ) was created to facilitate early detection of feeding and swallowing problems. This is…”
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A reciprocal translocation dissects roles of Pax6 alternative promoters and upstream regulatory elements in the development of pancreas, brain, and eye
Published in Genesis (New York, N.Y. : 2000) (01-09-2013)“…Pax6 encodes a transcription factor with key roles in the development of the pancreas, central nervous system, and eye. Gene expression is orchestrated by…”
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