Search Results - "Thompson, Fiona M."

Comparison of Modeling Methods to Determine Liver-to-blood Inocula and Parasite Multiplication Rates During Controlled Human Malaria Infection by Douglas, Alexander D., Edwards, Nick J., Duncan, Christopher J. A., Thompson, Fiona M., Sheehy, Susanne H., O'Hara, Geraldine A., Anagnostou, Nicholas, Walther, Michael, Webster, Daniel P., Dunachie, Susanna J., Porter, David W., Andrews, Laura, Gilbert, Sarah C., Draper, Simon J., Hill, Adrian V. S., Bejon, Philip

“…Controlled human malaria infection is used to measure efficacy of candidate malaria vaccines before field studies are undertaken. Mathematical modeling using…”
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Evidence of blood stage efficacy with a virosomal malaria vaccine in a phase IIa clinical trial by Thompson, Fiona M, Porter, David W, Okitsu, Shinji L, Westerfeld, Nicole, Vogel, Denise, Todryk, Stephen, Poulton, Ian, Correa, Simon, Hutchings, Claire, Berthoud, Tamara, Dunachie, Susanna, Andrews, Laura, Williams, Jack L, Sinden, Robert, Gilbert, Sarah C, Pluschke, Gerd, Zurbriggen, Rinaldo, Hill, Adrian V S

“…Previous research indicates that a combination vaccine targeting different stages of the malaria life cycle is likely to provide the most effective malaria…”
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MAIT cells are activated during human viral infections by van Wilgenburg, Bonnie, Scherwitzl, Iris, Hutchinson, Edward C., Leng, Tianqi, Kurioka, Ayako, Kulicke, Corinna, de Lara, Catherine, Cole, Suzanne, Vasanawathana, Sirijitt, Limpitikul, Wannee, Malasit, Prida, Young, Duncan, Denney, Laura, Moore, Michael D., Fabris, Paolo, Giordani, Maria Teresa, Oo, Ye Htun, Laidlaw, Stephen M., Dustin, Lynn B., Ho, Ling-Pei, Thompson, Fiona M., Ramamurthy, Narayan, Mongkolsapaya, Juthathip, Willberg, Christian B., Screaton, Gavin R., Klenerman, Paul

“…Mucosal-associated invariant T (MAIT) cells are abundant in humans and recognize bacterial ligands. Here, we demonstrate that MAIT cells are also activated…”
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Crypt Fission Peaks Early During Infancy and Crypt Hyperplasia Broadly Peaks During Infancy and Childhood in the Small Intestine of Humans by Cummins, Adrian G, Catto‐Smith, Anthony G, Cameron, Donald J, Couper, Richard T, Davidson, Geoffrey P, Day, Andrew S, Hammond, Paul D, Moore, David J, Thompson, Fiona M

“…ABSTRACT Background: Postnatal growth of the small intestine occurs by crypt hyperplasia and by the less recognised mechanism of crypt fission. How the small…”
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Safety, Immunogenicity, and Efficacy of Prime-Boost Immunization with Recombinant Poxvirus FP9 and Modified Vaccinia Virus Ankara Encoding the Full-Length Plasmodium falciparum Circumsporozoite Protein by Walther, Michael, Thompson, Fiona M, Dunachie, Susanna, Keating, Sheila, Todryk, Stephen, Berthoud, Tamara, Andrews, Laura, Andersen, Rikke F, Moore, Anne, Gilbert, Sarah C, Poulton, Ian, Dubovsky, Filip, Tierney, Eveline, Correa, Simon, Huntcooke, Angela, Butcher, Geoffrey, Williams, Jack, Sinden, Robert E, Hill, Adrian V. S

“…Heterologous prime-boost immunization with DNA and various recombinant poxviruses encoding malaria antigens is capable of inducing strong cell-mediated immune…”
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Impact on malaria parasite multiplication rates in infected volunteers of the protein-in-adjuvant vaccine AMA1-C1/Alhydrogel+CPG 7909 by Duncan, Christopher J A, Sheehy, Susanne H, Ewer, Katie J, Douglas, Alexander D, Collins, Katharine A, Halstead, Fenella D, Elias, Sean C, Lillie, Patrick J, Rausch, Kelly, Aebig, Joan, Miura, Kazutoyo, Edwards, Nick J, Poulton, Ian D, Hunt-Cooke, Angela, Porter, David W, Thompson, Fiona M, Rowland, Ros, Draper, Simon J, Gilbert, Sarah C, Fay, Michael P, Long, Carole A, Zhu, Daming, Wu, Yimin, Martin, Laura B, Anderson, Charles F, Lawrie, Alison M, Hill, Adrian V S, Ellis, Ruth D

“…Inhibition of parasite growth is a major objective of blood-stage malaria vaccines. The in vitro assay of parasite growth inhibitory activity (GIA) is widely…”
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Postnatal Changes in mucosal immune response: A physiological perspective of breast feeding and weaning by Cummins, Adrian G, Thompson, Fiona M

“…There are profound changes of immune activity during infancy from suppression during breast feeding, activation with weaning, and later intrinsic…”
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Morphometric Evaluation of Duodenal Biopsies in Celiac Disease by CUMMINS, Adrian G, ALEXANDER, Basile G, CHUNG, Adrian, TEO, Edward, WOENIG, Josh A, FIELD, John B. J, THOMPSON, Fiona M, ROBERTS-THOMSON, Ian C

“…The Marsh classification is a semiquantitative method for the diagnosis and monitoring of changes in duodenal biopsies in celiac disease. We have explored the…”
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Multiple functions of human T cells generated by experimental malaria challenge by Todryk, Stephen M, Walther, Michael, Bejon, Philip, Hutchings, Claire, Thompson, Fiona M, Urban, Britta C, Porter, David W, Hill, Adrian V.S

“…Protective immunity generated following malaria infection may be comprised of Ab or T cells against malaria Ag of different stages; however, the short-lived…”
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Deficiency of 6B11+ Invariant NK T-Cells in Celiac Disease by Grose, Randall H., Thompson, Fiona M., Cummins, Adrian G.

“…Immunoregulatory NK T-cells are deficient in certain autoimmune diseases. The purpose of this study was to investigate any deficiency of immunoregulatory NK…”
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Deficiency of invariant NK T cells in Crohn's disease and ulcerative colitis by GROSE, Randall H, THOMPSON, Fiona M, BAXTER, Alan G, PELLICCI, Daniel G, CUMMINS, Adrian G

“…The aim of this study was to investigate whether immunoregulatory invariant NK T cells are deficient in Crohn's disease or ulcerative colitis. Blood was…”
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Correction: Multiple functions of human T cells generated by experimental malaria challenge by Todryk, Stephen M., Walther, Michael, Bejon, Philip, Hutchings, Claire, Thompson, Fiona M., Urban, Britta C., Porter, David W., Hill, Adrian V. S.

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A human Phase I/IIa malaria challenge trial of a polyprotein malaria vaccine by Porter, David W, Thompson, Fiona M, Berthoud, Tamara K, Hutchings, Claire L, Andrews, Laura, Biswas, Sumi, Poulton, Ian, Prieur, Eric, Correa, Simon, Rowland, Rosalind, Lang, Trudie, Williams, Jackie, Gilbert, Sarah C, Sinden, Robert E, Todryk, Stephen, Hill, Adrian V.S

“…Abstract We examined the safety, immunogenicity and efficacy of a prime-boost vaccination regime involving two poxvirus malaria subunit vaccines, FP9-PP and…”
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Activation of β-catenin in the stem cell region of crypts during growth of the small intestine in infant rats by CAMAC, Kimberley S, THOMPSON, Fiona M, CUMMINS, Adrian G

“…The Wnt/beta-catenin pathway has been proposed as promoting intestinal stem cell division. Wnt ligands activate cytoplasmic beta-catenin and increase nuclear…”
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Postnatal epithelial growth of the small intestine in the rat occurs by both crypt fission and crypt hyperplasia by CUMMINS, Adrian G, JONES, Ben J, THOMPSON, Fiona M

“…Studies of growth of the small intestine have largely concentrated on crypt hyperplasia rather than crypt fission. The aim of this study was to investigate…”
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Effect of interleukin-11 on ameliorating intestinal damage after methotrexate treatment of breast cancer in rats by GIBSON, Rachel J, KEEFE, Dorothy M. K, THOMPSON, Fiona M, CLARKE, Julie M, GOLAND, Gary J, CUMMINS, Adrian G

“…Gastrointestinal mucositis after cancer chemotherapy is an increasing problem that is essentially untreatable once established, although it gradually remits…”
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The effect of keratinocyte growth factor on tumour growth and small intestinal mucositis after chemotherapy in the rat with breast cancer by GIBSON, Rachel J, KEEFE, Dorothy M. K, CLARKE, Julie M, REGESTER, Geoff O, THOMPSON, Fiona M, GOLAND, Gary J, EDWARDS, Ben G, CUMMINS, Adrian G

“…Mucositis from cancer chemotherapy is a common problem for which there is no definitive treatment. It produces significant morbidity and occasional mortality…”
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Improvement in intestinal permeability precedes morphometric recovery of the small intestine in coeliac disease by Cummins, A G, Thompson, F M, Butler, R N, Cassidy, J C, Gillis, D, Lorenzetti, M, Southcott, E K, Wilson, P C

“…It is often difficult to assess small bowel recovery in adults with coeliac disease on a gluten-free diet (GFD). This prospective study compares changes in…”
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Epithelial Growth of the Small Intestine in Human Infants by Thompson, Fiona M, Catto-Smith, Anthony G, Moore, David, Davidson, Geoff, Cummins, Adrian G

“…BACKGROUND:Findings in studies in rodents have suggested that epithelial growth of the small intestine is dependent on activation of the immune system. The…”
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Re: Antibody and genetic testing in coeliac disease by Cummins, Adrian G., Thompson, Fiona M., Gillis, David

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