Search Results - "Thompson, Christine S"

The validity and responsiveness of three quality of life measures in the assessment of psoriasis patients: results of a phase II study by Shikiar, Richard, Willian, Mary Kaye, Okun, Martin M, Thompson, Christine S, Revicki, Dennis A

“…Patient-reported outcome (PROs) measures are being used more frequently in investigational studies of treatments for moderate to severe plaque psoriasis. The…”
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Discovery of GSK1070916, a Potent and Selective Inhibitor of Aurora B/C Kinase by Adams, Nicholas D, Adams, Jerry L, Burgess, Joelle L, Chaudhari, Amita M, Copeland, Robert A, Donatelli, Carla A, Drewry, David H, Fisher, Kelly E, Hamajima, Toshihiro, Hardwicke, Mary Ann, Huffman, William F, Koretke-Brown, Kristin K, Lai, Zhihong V, McDonald, Octerloney B, Nakamura, Hiroko, Newlander, Ken A, Oleykowski, Catherine A, Parrish, Cynthia A, Patrick, Denis R, Plant, Ramona, Sarpong, Martha A, Sasaki, Kosuke, Schmidt, Stanley J, Silva, Domingos J, Sutton, David, Tang, Jun, Thompson, Christine S, Tummino, Peter J, Wang, Jamin C, Xiang, Hong, Yang, Jingsong, Dhanak, Dashyant

“…The Aurora kinases play critical roles in the regulation of mitosis and are frequently overexpressed or amplified in human tumors. Selective inhibitors may…”
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Synthesis and SAR of cis-1-Benzoyl-1,2,3,4-tetrahydroquinoline ligands for control of gene expression in ecdysone responsive systems by Smith, Howard C, Cavanaugh, Caitlin K, Friz, Jennifer L, Thompson, Christine S, Saggers, Jessica A, Michelotti, Enrique L, Garcia, Javier, Tice, Colin M

“…A library of 35 cis-1-benzoyl-2-methyl-4-(phenylamino)-1,2,3,4-tetrahydroquinolines was prepared. The compounds bore various substitutuents on the benzoyl…”
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Optimization of α-acylaminoketone ecdysone agonists for control of gene expression by Tice, Colin M., Hormann, Robert E., Thompson, Christine S., Friz, Jennifer L., Cavanaugh, Caitlin K., Saggers, Jessica A.

“…Fifteen new α-acylaminoketones were prepared by four different routes in an initial effort to optimize the potency of these compounds as ecdysone agonists. The…”
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Synthesis and SAR of α-Acylaminoketone ligands for control of gene expression by Tice, Colin M, Hormann, Robert E, Thompson, Christine S, Friz, Jennifer L, Cavanaugh, Caitlin K, Michelotti, Enrique L, Garcia, Javier, Nicolas, Ernesto, Albericio, Fernando

“…A lead discovery library and a follow-up focused library of α-acylaminoketones were designed based on known dibenzoylhydrazine ecdysone agonists, including GS…”
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Abstract 4700: A novel selective EZH2 inhibitor exhibits anti-tumor activity in lymphoma with EZH2 activating mutations by Creasy, Caretha L., McCabe, Michael T., Korenchuk, Susan, Diaz, Elsie, Ott, Heidi, Thompson, Christine S., Ganji, Gopi, Gorman, Shelby A., LaFrance, Louis V., Brandt, Martin, McHugh, Charles, Verma, Sharad K., Tummino, Peter J.

“…Abstract EZH2 is the catalytic subunit of the Polycomb Repressive Complex 2 (PRC2) responsible for methylating histone H3 on lysine 27 (H3K27) and repressing…”
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Epidural anesthesia worsens uterine blood flow and fetal oxygenation during hemorrhage in gravid ewes by VINCENT, R. D, CHESTNUT, D. H, SIPES, S. L, DEBRYUN, C. S, CHATTERJEE, P, THOMPSON, C. S

“…Recent studies suggest that epidural anesthesia initiated before hemorrhage may improve survival and acid-base status in laboratory animals. However, studies…”
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Does indomethacin alter the hemodynamic response to magnesium sulfate infusion and hemorrhage in gravid ewes? by Chestnut, D H, Weiner, C P, Thompson, C S, DeBruyn, C S

“…The purpose of this study was to determine whether indomethacin alters the maternal and fetal hemodynamic response to magnesium sulfate (MgSO4) infusion and…”
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999. Development of Orthogonal Multiplex Gene-Switch Systems Based on Engineered Ecdysone Receptors and Inducing Ligands Selected from a Single Chemotype by Friz, Jennifer L, Vertin, Beth, Thompson, Christine S, Palli, Subba R, Kuman, Mohan, Chortyk, Orestes, Meyer, Andy, Meteyer, Tom, Smith, Howard, Hormann, Robert E, Cress, Dean E

“…Drug-inducible regulation of multiple genes independently and simultaneously is a highly desirable gene therapy capability. Actuation of a plurality of genes…”
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Safe Passage: a Nurse-Led Multidisciplinary Team Approach to Improving Transitions and Reducing Readmissions for Heart Failure Patients by Thompson, Christine, MS, BS

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Translating Clinical Findings into the Patient’s Perspective: Post-hoc Pooled Analysis of Bowel Movement Changes as a Predictor of Improvement in Patients’ Opioid-induced Constipation Symptoms and Outcomes by Coyne, Karin S., PhD, MPH, Poon, Jiat-Ling, PhD, Thompson, Christine, BS, Hu, Yiqun, MD, PhD, Datto, Catherine J., MD, MS, Sostek, Mark, MD

“…Abstract Purpose Opioid-induced constipation (OIC) is a bothersome side effect of opioid use for the management of noncancer pain, affecting patients’…”
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An Electronic Medical Record Report Improves Identification of Hospitalized Patients With Heart Failure by Banerjee, Dipanjan, MD, MS, Thompson, Christine, MS, RN, CNS, CCRN-K, CHFN, Bingham, Angela, RN, MSN, CNL, Kell, Charlene, MBA, BSN, RN, CCRN, FACHE, Duhon, Julie, BA, Grossman, Helene, PhD

“…Abstract Background Early identification of inpatients with heart failure (HF) may help to reduce readmissions. We found that many patients identified by our…”
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Does the intravenous infusion of ritodrine or magnesium sulfate alter the hemodynamic response to hemorrhage in gravid ewes? by Chestnut, D H, Thompson, C S, McLaughlin, G L, Weiner, C P

“…The purpose of this study was to determine whether the intravenous infusion of ritodrine or magnesium sulfate alters the hemodynamic response to maternal…”
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Does ritodrine worsen maternal hypotension during epidural anesthesia in gravid ewes? by CHESTNUT, D. H, POLLACK, K. L, THOMPSON, C. S, DEBRUYN, C. S, WEINERE, C. P

“…The purpose of this study was to determine whether prior administration ritodrine worsens maternal hypotension during epidural anesthesia in gravid ewes…”
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Does furosemide alter the hemodynamic response to rapid intravascular transfusion of the anemic fetal lamb? by Chestnut, D H, Pollack, K L, Weiner, C P, Robillard, J E, Thompson, C S, DeBruyn, C S

“…The purpose of this study was to define the hemodynamic response to rapid intravascular transfusion of the anemic fetal lamb and to determine whether…”
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Magnesium sulfate and promethazine do not interact to cause hypotension in gravid ewes by Pollack, K L, Chestnut, D H, Weiner, C P, Thompson, C S, DeBruyn, C S

“…The purpose of this study was to determine whether magnesium sulfate and promethazine interact to cause hypotension in gravid ewes. Fifteen experiments were…”
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Chlordiazepoxide (librium)-induced changes in intraspecific attack and selected non-agonistic behaviors in male Siamese fighting fish by Figler, M H, Klein, R M, Thompson, C S

“…Two experiments were undertaken to determine the effects of chlordiazepoxide on intraspecific attack behavior and selected non-aggressive behaviors in male…”
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