Search Results - "Thompson, Carol L."
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CORTECON: A Temporal Transcriptome Analysis of In Vitro Human Cerebral Cortex Development from Human Embryonic Stem Cells
Published in Neuron (Cambridge, Mass.) (02-07-2014)“…Many neurological and psychiatric disorders affect the cerebral cortex, and a clearer understanding of the molecular processes underlying human corticogenesis…”
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Allen Brain Atlas: an integrated spatio-temporal portal for exploring the central nervous system
Published in Nucleic acids research (01-01-2013)“…The Allen Brain Atlas (http://www.brain-map.org) provides a unique online public resource integrating extensive gene expression data, connectivity data and…”
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A High-Resolution Spatiotemporal Atlas of Gene Expression of the Developing Mouse Brain
Published in Neuron (Cambridge, Mass.) (16-07-2014)“…To provide a temporal framework for the genoarchitecture of brain development, we generated in situ hybridization data for embryonic and postnatal mouse brain…”
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A Single-Cell Roadmap of Lineage Bifurcation in Human ESC Models of Embryonic Brain Development
Published in Cell stem cell (05-01-2017)“…During human brain development, multiple signaling pathways generate diverse cell types with varied regional identities. Here, we integrate single-cell RNA…”
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Sleep Deprivation Effects on Circadian Clock Gene Expression in the Cerebral Cortex Parallel Electroencephalographic Differences among Mouse Strains
Published in The Journal of neuroscience (09-07-2008)“…Sleep deprivation (SD) results in increased electroencephalographic (EEG) delta power during subsequent non-rapid eye movement sleep (NREMS) and is associated…”
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Cell-type-specific consequences of reelin deficiency in the mouse neocortex, hippocampus, and amygdala
Published in Journal of comparative neurology (1911) (01-08-2011)“…The disrupted cortical lamination phenotype in reeler mice and subsequent identification of the Reelin signaling pathway have strongly informed models of…”
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Posttranslational Regulation of the Mammalian Circadian Clock by Cryptochrome and Protein Phosphatase 5
Published in Proceedings of the National Academy of Sciences - PNAS (05-07-2006)“…The molecular oscillator that drives circadian rhythmicity in mammals obtains its near 24-h periodicity from posttranslational regulation of clock proteins…”
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Molecular and anatomical signatures of sleep deprivation in the mouse brain
Published in Frontiers in neuroscience (2010)“…Sleep deprivation (SD) leads to a suite of cognitive and behavioral impairments, and yet the molecular consequences of SD in the brain are poorly understood…”
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Photolyase/cryptochrome blue-light photoreceptors use photon energy to repair DNA and reset the circadian clock
Published in Oncogene (16-12-2002)“…Blue light governs a number of cellular responses in bacteria, plants, and animals, including photoreactivation, plant development, and circadian…”
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Light Induction of a Vertebrate Clock Gene Involves Signaling through Blue-Light Receptors and MAP Kinases
Published in Current biology (14-05-2002)“…The signaling pathways that couple light photoreception to entrainment of the circadian clock have yet to be deciphered. Two prominent groups of candidates for…”
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Transcriptional network orchestrating regional patterning of cortical progenitors
Published in Proceedings of the National Academy of Sciences - PNAS (21-12-2021)“…We uncovered a transcription factor (TF) network that regulates cortical regional patterning in radial glial stem cells. Screening the expression of hundreds…”
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Expression of the Blue-Light Receptor Cryptochrome in the Human Retina
Published in Investigative ophthalmology & visual science (01-10-2003)“…To analyze the patterns of expression of the cryptochromes, CRY1 and CRY2, in the human retina and to correlate expression of these putative blue-light…”
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Genomic Anatomy of the Hippocampus
Published in Neuron (Cambridge, Mass.) (26-12-2008)“…Availability of genome-scale in situ hybridization data allows systematic analysis of genetic neuroanatomical architecture. Within the hippocampus,…”
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Society of Critical Care Medicine Presidential Address–42nd Annual Congress, January 2013, San Juan, Puerto Rico
Published in Critical care medicine (01-05-2013)Get full text
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Aberrant Cortical Activity in Multiple GCaMP6-Expressing Transgenic Mouse Lines
Published in eNeuro (01-09-2017)“…Transgenic mouse lines are invaluable tools for neuroscience but, as with any technique, care must be taken to ensure that the tool itself does not unduly…”
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Single-Cell Profiling of an In Vitro Model of Human Interneuron Development Reveals Temporal Dynamics of Cell Type Production and Maturation
Published in Neuron (Cambridge, Mass.) (08-03-2017)“…GABAergic interneurons are essential for neural circuit function, and their loss or dysfunction is implicated in human neuropsychiatric disease. In vitro…”
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Preservation of Light Signaling to the Suprachiasmatic Nucleus in Vitamin A-Deficient Mice
Published in Proceedings of the National Academy of Sciences - PNAS (25-09-2001)“…To investigate the role of retinal-based pigments (opsins) in circadian photoreception in mice, animals mutated in plasma retinol binding protein were placed…”
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Pain behaviors observed during six common procedures: Results from Thunder Project II
Published in Critical care medicine (01-02-2004)“…OBJECTIVEPatients frequently display behaviors during procedures that may be pain related. Clinicians often rely on the patient’s demonstration of behaviors as…”
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Quantitative methods for genome-scale analysis of in situ hybridization and correlation with microarray data
Published in Genome biology (30-01-2008)“…With the emergence of genome-wide colorimetric in situ hybridization (ISH) data sets such as the Allen Brain Atlas, it is important to understand the…”
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