Search Results - "Thompson, CM"

Activation of G-proteins by morphine and codeine congeners: insights to the relevance of O- and N-demethylated metabolites at mu- and delta-opioid receptors by Thompson, Chad M, Wojno, Heidi, Greiner, Elisabeth, May, Everette L, Rice, Kenner C, Selley, Dana E

“…Phenotypic differences in analgesic sensitivity to codeine (3-methoxymorphine) results from polymorphisms in cytochrome P450-2D6, which catalyzes…”
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Synthesis and in Vitro Pharmacology of Substituted Quinoline-2,4-dicarboxylic Acids as Inhibitors of Vesicular Glutamate Transport by Carrigan, Christina N, Bartlett, Richard D, Esslinger, C. Sean, Cybulski, Kimberly A, Tongcharoensirikul, Pakamas, Bridges, Richard J, Thompson, Charles M

“…The vesicular glutamate transport (VGLUT) system selectively mediates the uptake of l-glutamate into synaptic vesicles. Uptake is linked to an H+-ATPase that…”
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Substituted quinolines as inhibitors of l-glutamate transport into synaptic vesicles by Bartlett, R.D., Esslinger, C.S., Thompson, C.M., Bridges, R.J.

“…This study investigated the structure–activity relationships and kinetic properties of a library of kynurenate analogues as inhibitors of 3H- l-glutamate…”
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The value of a scoring system for hypoxic ischaemic encephalopathy in predicting neurodevelopmental outcome by Thompson, CM, Puterman, AS, Linley, LL, Hann, FM, van der Elst, CW, Molteno, CD, Malan, AF

“…A numeric scoring system for the assessment of hypoxic ischaemic encephalopathy during the neonatal period was tested. The value of the score in predicting…”
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Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment by Johnson, G.E., Soeteman-Hernández, L.G., Gollapudi, B.B., Bodger, O.G., Dearfield, K.L., Heflich, R.H., Hixon, J.G., Lovell, D.P., MacGregor, J.T., Pottenger, L.H., Thompson, C.M., Abraham, L., Thybaud, V., Tanir, J.Y., Zeiger, E., van Benthem, J., White, P.A.

“…Genetic toxicology data have traditionally been employed for qualitative, rather than quantitative evaluations of hazard. As a continuation of our earlier…”
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CD4+T Cells Mediate Antibody-Independent Acquired Immunity to Pneumococcal Colonization by Malley, Richard, Trzcinski, Krzysztof, Srivastava, Amit, Thompson, Claudette M., Anderson, Porter W., Lipsitch, Marc, Bloom, Barry R.

“…Acquired immunity to Streptococcus pneumoniae (pneumococcus) has long been assumed to depend on the presence of anticapsular antibodies. We found, however,…”
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Transcriptional Regulatory Networks in Saccharomyces cerevisiae by Lee, Tong Ihn, Rinaldi, Nicola J., Robert, François, Odom, Duncan T., Bar-Joseph, Ziv, Gerber, Georg K., Hannett, Nancy M., Harbison, Christopher T., Thompson, Craig M., Simon, Itamar, Zeitlinger, Julia, Jennings, Ezra G., Murray, Heather L., Gordon, D. Benjamin, Ren, Bing, Wyrick, John J., Tagne, Jean-Bosco, Volkert, Thomas L., Fraenkel, Ernest, Gifford, David K., Young, Richard A.

“…We have determined how most of the transcriptional regulators encoded in the eukaryote Saccharomyces cerevisiae associate with genes across the genome in…”
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Recognition of Pneumolysin by Toll-like Receptor 4 Confers Resistance to Pneumococcal Infection by Malley, Richard, Henneke, Philipp, Morse, Sarah C., Cieslewicz, Michael J., Lipsitch, Marc, Thompson, Claudette M., Kurt-Jones, Evelyn, Paton, James C., Wessels, Michael R., Golenbock, Douglas T.

“…Streptococcus pneumoniae is one of the leading causes of invasive bacterial disease worldwide. Fragments of the cell wall and the cytolytic toxin pneumolysin…”
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Antibody-Independent, Interleukin-17A-Mediated, Cross-Serotype Immunity to Pneumococci in Mice Immunized Intranasally with the Cell Wall Polysaccharide by Malley, Richard, Srivastava, Amit, Lipsitch, Marc, Thompson, Claudette M, Watkins, Claire, Tzianabos, Arthur, Anderson, Porter W

“…Serotype-specific immunity to Streptococcus pneumoniae is conferred by antibodies to the capsular polysaccharides, which define the 90 known serotypes. Whether…”
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Barbiturate-induced expression of neuronal nitric oxide synthase in the rat cerebellum by Thompson, Chad M, Bernhard, Anne E, Strobel, Henry W

“…Neuronal nitric oxide synthase (nNOS) is known to share some structural and functional similarities with the cytochrome P450 mixed function oxidase system…”
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Flame retardant aircraft epoxy resins containing phosphorus by Hergenrother, Paul M., Thompson, Craig M., Smith, Joseph G., Connell, John W., Hinkley, Jeffrey A., Lyon, Richard E., Moulton, Richard

“…As part of a program to develop fire resistant exterior composite structures for future subsonic commercial and general aviation aircraft, flame retardant…”
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Species-specific abundance of bivalve larvae in relation to biological and physical conditions in a Cape Cod estuary by Thompson, Christine M., York, Richard H., Gallager, Scott M.

“…Physical and biological conditions impact recruitment and adult population structure of marine invertebrates by affecting early life-history processes from…”
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Pneumococcal protein antigen serology varies with age and may predict antigenic profile of colonizing isolates by Azarian, T, Grant, LR, Georgieva, M, Hammitt, LL, Reid, R, Bentley, SD, Goldblatt, D, Santosham, M, Weatherholtz, R, Burbidge, P, Goklish, N, Thompson, CM, Hanage, WP, O’Brien, KL, Lipsitch, M

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Albumin, a New Biomarker of Organophosphorus Toxicant Exposure, Identified by Mass Spectrometry by Peeples, Eric S., Schopfer, Lawrence M., Duysen, Ellen G., Spaulding, Reggie, Voelker, Troy, Thompson, Charles M., Lockridge, Oksana

“…The classical laboratory tests for exposure to organophosphorus toxicants (OP) are inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE)…”
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Formaldehyde dehydrogenase: Beyond phase I metabolism by Thompson, Chad M., Ceder, Rebecca, Grafström, Roland C.

“…Formaldehyde dehydrogenase, formally Class III alcohol dehydrogenase (ADH3), has recently been discovered to partially regulate nitrosothiol homeostasis by…”
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The influence of research scale on bald eagle habitat selection along the lower Hudson River, New York (USA) by THOMPSON, Craig M, MCGARIGAL, Kevin

“…As the concepts of landscape ecology have been incorporated into otherdisciplines, the influence of spatial patterns on animal abundance anddistribution has…”
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The role of complement in innate and adaptive immunity to pneumococcal colonization and sepsis in a murine model by Bogaert, D, Thompson, C.M, Trzcinski, K, Malley, R, Lipsitch, M

“…Abstract Streptococcus pneumoniae is an important bacterial cause of sepsis, meningitis, pneumonia and otitis media. Pneumococcal disease is generally preceded…”
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The synaptic vesicle proteome: A comparative study in membrane protein identification by Coughenour, Holly D., Spaulding, Reggie S., Thompson, Charles M.

“…A proteomic analysis of the synaptic vesicle was undertaken to obtain a better understanding of vesicle regulation. Synaptic vesicles primarily consist of…”
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Phosphonate Analogues of α-Ketoglutarate Inhibit the Activity of the α-Ketoglutarate Dehydrogenase Complex Isolated from Brain and in Cultured Cells by Bunik, Victoria I, Denton, Travis T, Xu, Hui, Thompson, Charles M, Cooper, Arthur J. L, Gibson, Gary E

“…The α-ketoglutarate dehydrogenase complex (KGDHC), a control point of the tricarboxylic acid cycle, is partially inactivated in brain in many neurodegenerative…”
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Considerations for the implausibility of leukemia induction by formaldehyde by Thompson, Chad M, Grafström, Roland C

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