Search Results - "Thompson, Alfred"

The impact of patient choice on survival in chronic thromboembolic pulmonary hypertension by Quadery, Syed Rehan, Swift, Andrew J, Billings, Catherine G, Thompson, Alfred A R, Elliot, Charles A, Hurdman, Judith, Charalampopoulos, Athanasios, Sabroe, Ian, Armstrong, Iain J, Hamilton, Neil, Sephton, Paul, Garrad, Sian, Pepke-Zaba, Joanna, Jenkins, David P, Screaton, Nicholas, Rothman, Alexander M, Lawrie, Allan, Cleveland, Trevor, Thomas, Steven, Rajaram, Smitha, Hill, Catherine, Davies, Christine, Johns, Christopher S, Wild, Jim M, Condliffe, Robin, Kiely, David G

“…Pulmonary endarterectomy (PEA) is the gold standard treatment for operable chronic thromboembolic pulmonary hypertension (CTEPH). However, a proportion of…”
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Phenotyping of idiopathic pulmonary arterial hypertension: a registry analysis by Hoeper, Marius M, Dwivedi, Krit, Pausch, Christine, Lewis, Robert A, Olsson, Karen M, Huscher, Doerte, Pittrow, David, Grünig, Ekkehard, Staehler, Gerd, Vizza, Carmine Dario, Gall, Henning, Distler, Oliver, Opitz, Christian, Gibbs, John Simon R, Delcroix, Marion, Park, Da-Hee, Ghofrani, Hossein Ardeschir, Ewert, Ralf, Kaemmerer, Harald, Kabitz, Hans-Joachim, Skowasch, Dirk, Behr, Juergen, Milger, Katrin, Lange, Tobias J, Wilkens, Heinrike, Seyfarth, Hans-Jürgen, Held, Matthias, Dumitrescu, Daniel, Tsangaris, Iraklis, Vonk-Noordegraaf, Anton, Ulrich, Silvia, Klose, Hans, Claussen, Martin, Eisenmann, Stephan, Schmidt, Kai-Helge, Swift, Andrew J, Thompson, Alfred A Roger, Elliot, Charlie A, Rosenkranz, Stephan, Condliffe, Robin, Kiely, David G, Halank, Michael

“…Among patients meeting diagnostic criteria for idiopathic pulmonary arterial hypertension (IPAH), there is an emerging lung phenotype characterised by a low…”
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Hypoxia selectively inhibits respiratory burst activity and killing of Staphylococcus aureus in human neutrophils by McGovern, Naomi N, Cowburn, Andrew S, Porter, Linsey, Walmsley, Sarah R, Summers, Charlotte, Thompson, Alfred A R, Anwar, Sadia, Willcocks, Lisa C, Whyte, Moira K B, Condliffe, Alison M, Chilvers, Edwin R

“…Neutrophils play a central role in the innate immune response and a critical role in bacterial killing. Most studies of neutrophil function have been conducted…”
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Bosutinib therapy resulting in severe deterioration of pre-existing pulmonary arterial hypertension by Hickey, Peter M, Thompson, Alfred A R, Charalampopoulos, Athanasios, Elliot, Charles A, Hamilton, Neil, Kiely, David G, Lawrie, Allan, Sabroe, Ian, Condliffe, Robin

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Deficiency of tumour necrosis factor-related apoptosis-inducing ligand exacerbates lung injury and fibrosis by McGrath, Emmet E, Lawrie, Allan, Marriott, Helen M, Mercer, Paul, Cross, Simon S, Arnold, Nadine, Singleton, Vanessa, Thompson, Alfred A R, Walmsley, Sarah R, Renshaw, Stephen A, Sabroe, Ian, Chambers, Rachel C, Dockrell, David H, Whyte, Moira K B

“…The death receptor ligand tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) shows considerable clinical promise as a therapeutic agent. TRAIL…”
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Inhibition of ErbB kinase signalling promotes resolution of neutrophilic inflammation by Rahman, Atiqur, Henry, Katherine M, Herman, Kimberly D, Thompson, Alfred Ar, Isles, Hannah M, Tulotta, Claudia, Sammut, David, Rougeot, Julien Jy, Khoshaein, Nika, Reese, Abigail E, Higgins, Kathryn, Tabor, Caroline, Sabroe, Ian, Zuercher, William J, Savage, Caroline O, Meijer, Annemarie H, Whyte, Moira Kb, Dockrell, David H, Renshaw, Stephen A, Prince, Lynne R

“…Neutrophilic inflammation with prolonged neutrophil survival is common to many inflammatory conditions, including chronic obstructive pulmonary disease (COPD)…”
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A decoy receptor 3 analogue reduces localised defects in phagocyte function in pneumococcal pneumonia by Marriott, Helen M, Daigneault, Marc, Thompson, Alfred A R, Walmsley, Sarah R, Gill, Sharonjit K, Witcher, Derrick R, Wroblewski, Victor J, Hellewell, Paul G, Whyte, Moira K B, Dockrell, David H

“…Therapeutic strategies to modulate the host response to bacterial pneumonia are needed to improve outcomes during community-acquired pneumonia. This study used…”
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Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice by Walmsley, Sarah R, Chilvers, Edwin R, Thompson, Alfred A, Vaughan, Kathryn, Marriott, Helen M, Parker, Lisa C, Shaw, Gary, Parmar, Selina, Schneider, Martin, Sabroe, Ian, Dockrell, David H, Milo, Marta, Taylor, Cormac T, Johnson, Randall S, Pugh, Christopher W, Ratcliffe, Peter J, Maxwell, Patrick H, Carmeliet, Peter, Whyte, Moira K B

“…The regulation of neutrophil lifespan by induction of apoptosis is critical for maintaining an effective host response and preventing excessive inflammation…”
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Manual Assessment of the Initial Fall in Blood Pressure After Orthostatic Challenge at High Altitude by Mytton, Oliver T, Simpson, Alistair, Thompson, Alfred A. R, Oram, Richard A, Darowski, Adam, Yu, Ly-Mee, Collier, David J, Pollard, Andrew J

“…Objective.—Dizziness is a symptom of acute mountain sickness (AMS). This study tested whether immediate fall in systolic blood pressure (BP) on standing was…”
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Catastrophe for a campanologist by Thompson, Alfred A.R, McRoberts, Randal J, McKie, Scott, Oglesby, Angela J

“…A campanologist was involved in a nonfatal hanging incident. On presentation she had no midline bony tenderness and only subtle abnormalities on plain X-ray…”
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Abstract 10848: Adar1 Mediated Rna Editing Contributes to Vascular Remodeling by Kim, Hyunbum, Liu, Yu, Klouda, Timothy, Schumacher, Valerie A, Thompson, Alfred A, Wu, Joseph C, Li, Jin Billy, Raby, Benjamin, Yuan, Ke

“…IntroAdenosine deaminases acting on RNA 1 (ADAR1) catalyzes the conversion of adenosine (A) to inosine (I) on RNA transcripts. Due to the host immune response…”
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Abstract 13553: Remote Monitoring of the Haemodynamic Response to Clinically Indicated Therapeutic Escalation and Clinical Worsening Events in Patients With Pulmonary Arterial Hypertension by Middleton, Jennifer T, Binmahfooz, Sarah, Zafar, Hamza, Patel, Junaid, Giri, Dharshan, Battersby, Christian, Toshner, Mark, Reddy, Ashwin, Lewis, Robert, Condliffe, Robin, Elliot, Charlie, Hameed, Abdul, Charalampopoulos, Athanasios, Thompson, Alfred, Kiely, David G, Rothman, Alex M

“…Background Hospital-based assessment of haemodynamics, exercise capacity and right heart function/strain are used for risk-stratification to aid clinical…”
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Abstract 13527: The Development of a Remote Pulmonary Arterial Hypertension Risk Score Utilising Remote Monitoring Technology to Monitor Parameters Associated With Mortality in Pulmonary Arterial Hypertension by Middleton, Jennifer T, Binmahfooz, Sarah, Zafar, Hamza, Patel, Junaid, Neelam Naganathan, Dharshan Giri, Battersby, Christian, Toshner, Mark, Reddy, Ashwin, Lewis, Robert, Swift, Andrew J, Condliffe, Robin, Elliot, Charlie, Hameed, Abdul, Charalampopoulos, Athanasios, Thompson, Alfred, Kiely, David G, Rothman, Alex M

“…BackgroundIn patients with pulmonary arterial hypertension (PAH) risk stratification is used to aid clinical decision making and guide treatment categorising…”
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Abstract 13581: Heart Rhythm versus Heart Rate Control Strategy in Patients With Pre-Capillary Pulmonary Hypertension and Atrial Arrhythmias by Sammut, Mark Anthony, Condliffe, Robin, Hameed, Abdul, Rothman, Alex M, Kyriacou, Andreas, Lewis, Robert A, Durrington, Charlotte, Elliot, Charlie A, Thompson, Alfred A, Sabroe, Ian, Kiely, David G, Charalampopoulos, Athanasios

“…IntroductionAtrial tachyarrhythmias in patients with pre-capillary pulmonary hypertension are often poorly tolerated leading to increased morbidity and…”
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Hypoxia Modulates Platelet Purinergic Signalling Pathways by Paterson, Gordon G, Young, Jason M, Willson, Joseph A, Graham, Christopher J, Dru, Rebecca C, Lee, Eleanor W, Torpey, Greig S, Walmsley, Sarah R, Chan, Melissa V, Warner, Timothy D, Baillie, John Kenneth, Thompson, Alfred Arthur Roger

“…Hypoxia resulting from ascent to high-altitude or pathological states at sea level is known to increase platelet reactivity. Previous work from our group has…”
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Abstract 16023: Vascular Smooth Muscle Derived TRAIL is Required for Development of Pulmonary Arterial Hypertension in Sugen 5416 / Hypoxia Mice by Braithwaite, Adam T, Pickworth, Josephine A, Arnold, Nadine D, West, Laura E, Iremonger, James E, Thompson, Alfred A, Marriott, Helen M, Lawrie, Allan

“…IntroductionPulmonary arterial hypertension (PAH) is a rare but severe disease characterised by progressive pulmonary arterial remodelling and right…”
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The role of oxygen sensing pathways in infection and inflammation by Thompson, Alfred Arthur Roger

“…Many inflammatory diseases are characterised by persistent and inappropriate neutrophil activation, systemic or localised hypoxia and bacterial colonisation…”
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Is technology killing critical-thinking skills? by Thompson, Alfred, Crompton, Helen

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Placenta previa and preeclampsia complicating the management of renal transplant patients by Perry, C P, Collins, C B, Lordon, R E, Thompson, A L, Brekken, A L, Harris, R E

“…Presented are three patients who have delivered full-term normal infants after renal transplants from living related donors. One patient had a placenta previa…”
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The Market for Force: Privatizing Security by Thompson, Alfred R H

“…The United States has in recent years been making substantial use of such organizations in a variety of combat zones around the world, ranging from the hire of…”
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