Search Results - "Thomen, Robert"
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Regional ventilation changes in severe asthma after bronchial thermoplasty with (3)He MR imaging and CT
Published in Radiology (01-01-2015)“…To quantify regional lung ventilation in healthy volunteers and patients with severe asthma (both before and after thermoplasty) by using a combination of…”
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Single-Session Bronchial Thermoplasty Guided by 129Xe Magnetic Resonance Imaging. A Pilot Randomized Controlled Clinical Trial
Published in American journal of respiratory and critical care medicine (15-08-2020)“…Adverse events have limited the use of bronchial thermoplasty (BT) in severe asthma. Hall et al sought to evaluate the effectiveness and safety of using 129Xe…”
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Retrospective respiratory self‐gating and removal of bulk motion in pulmonary UTE MRI of neonates and adults
Published in Magnetic resonance in medicine (01-03-2017)“…Purpose To implement pulmonary three‐dimensional (3D) radial ultrashort echo‐time (UTE) MRI in non‐sedated, free‐breathing neonates and adults with…”
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Lung microstructure in adolescent idiopathic scoliosis before and after posterior spinal fusion
Published in PloS one (08-10-2020)“…Adolescent idiopathic scoliosis (AIS) is associated with decreased respiratory quality of life and impaired diaphragm function. Recent hyperpolarized helium…”
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Quantitative Magnetic Resonance Imaging of Bronchopulmonary Dysplasia in the Neonatal Intensive Care Unit Environment
Published in American journal of respiratory and critical care medicine (15-11-2015)“…Bronchopulmonary dysplasia (BPD) is a prevalent yet poorly characterized pulmonary complication of premature birth; the current definition is based solely on…”
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Morphological and quantitative evaluation of emphysema in chronic obstructive pulmonary disease patients: A comparative study of MRI with CT
Published in Journal of magnetic resonance imaging (01-12-2016)“…Purpose To further validate the ability of ultrashort echo‐time (UTE) magnetic resonance imaging (MRI) in quantifying lung density in patients diagnosed with…”
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Human upper-airway respiratory airflow: In vivo comparison of computational fluid dynamics simulations and hyperpolarized 129Xe phase contrast MRI velocimetry
Published in PloS one (2021)“…Computational fluid dynamics (CFD) simulations of respiratory airflow have the potential to change the clinical assessment of regional airway function in…”
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Quantification of neonatal lung parenchymal density via ultrashort echo time MRI with comparison to CT
Published in Journal of magnetic resonance imaging (01-10-2017)“…Purpose To demonstrate that ultrashort echo time (UTE) magnetic resonance imaging (MRI) can achieve computed tomography (CT)‐like quantification of lung…”
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Pulmonary MRI of neonates in the intensive care unit using 3D ultrashort echo time and a small footprint MRI system
Published in Journal of magnetic resonance imaging (01-02-2017)“…Purpose To determine the feasibility of pulmonary magnetic resonance imaging (MRI) of neonatal lung structures enabled by combining two novel technologies:…”
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A single-breath-hold protocol for hyperpolarized 129 Xe ventilation and gas exchange imaging
Published in NMR in biomedicine (01-08-2023)“…Hyperpolarized Xe MRI (Xe-MRI) is increasingly used to image the structure and function of the lungs. Because Xe imaging can provide multiple contrasts…”
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A single‐breath‐hold protocol for hyperpolarized 129Xe ventilation and gas exchange imaging
Published in NMR in biomedicine (01-08-2023)“…Hyperpolarized 129Xe MRI (Xe‐MRI) is increasingly used to image the structure and function of the lungs. Because 129Xe imaging can provide multiple contrasts…”
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Regional Structure-Function in Cystic Fibrosis Lung Disease Using Hyperpolarized 129Xe and Ultrashort Echo Magnetic Resonance Imaging
Published in American journal of respiratory and critical care medicine (15-07-2020)“…Thomen discusses the study on the regional structure-function in cystic fibrosis (CF) lung disease using hyperpolarized 129 Xe and ultrashort echo magnetic…”
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Cyst Ventilation Heterogeneity and Alveolar Airspace Dilation as Early Disease Markers in Lymphangioleiomyomatosis
Published in Annals of the American Thoracic Society (01-08-2019)“…Lymphangioleiomyomatosis (LAM) is a rare disease associated with cystic destruction of the pulmonary parenchyma and chronic respiratory failure, and there are…”
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Improving hyperpolarized 129Xe ADC mapping in pediatric and adult lungs with uncertainty propagation
Published in NMR in biomedicine (01-03-2022)“…Rationale Hyperpolarized (HP) 129Xe‐MRI provides non‐invasive methods to quantify lung function and structure, with the 129Xe apparent diffusion coefficient…”
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Improving hyperpolarized 129 Xe ADC mapping in pediatric and adult lungs with uncertainty propagation
Published in NMR in biomedicine (01-03-2022)“…Hyperpolarized (HP) Xe-MRI provides non-invasive methods to quantify lung function and structure, with the Xe apparent diffusion coefficient (ADC) being a well…”
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Protocols for multi-site trials using hyperpolarized 129 Xe MRI for imaging of ventilation, alveolar-airspace size, and gas exchange: A position paper from the 129 Xe MRI clinical trials consortium
Published in Magnetic resonance in medicine (01-12-2021)“…Hyperpolarized (HP) Xe MRI uniquely images pulmonary ventilation, gas exchange, and terminal airway morphology rapidly and safely, providing novel information…”
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Protocols for multi‐site trials using hyperpolarized 129Xe MRI for imaging of ventilation, alveolar‐airspace size, and gas exchange: A position paper from the 129Xe MRI clinical trials consortium
Published in Magnetic resonance in medicine (01-12-2021)“…Hyperpolarized (HP) 129Xe MRI uniquely images pulmonary ventilation, gas exchange, and terminal airway morphology rapidly and safely, providing novel…”
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Single-Session Bronchial Thermoplasty Guided by 129 Xe Magnetic Resonance Imaging. A Pilot Randomized Controlled Clinical Trial
Published in American journal of respiratory and critical care medicine (15-08-2020)“…Adverse events have limited the use of bronchial thermoplasty (BT) in severe asthma. We sought to evaluate the effectiveness and safety of using Xe magnetic…”
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Preclinical hyperpolarized 129Xe MRI: ventilation and T2 mapping in mouse lungs at 7 T using multi‐echo flyback UTE
Published in NMR in biomedicine (01-07-2020)“…Fast apparent transverse relaxation (short T2*) is a common obstacle when attempting to perform quantitative 1H MRI of the lungs. While T2* times are longer…”
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