Search Results - "Thomas Winters"

Computers Learning Humor Is No Joke by Thomas Winters

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Immune Dysfunction from Radiation Exposure by Cassatt, David R., Winters, Thomas A., PrabhuDas, Mercy

“…Exposure to ionizing radiation causes acute damage and loss of bone marrow and peripheral immune cells that can result in high mortality due to reduced…”
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Minimum Reporting Standards Should be Expected for Preclinical Radiobiology Irradiators and Dosimetry in the Published Literature by Poirier, Yannick, DeWerd, Larry A., Trompier, François, Santos, Morgane Dos, Sheng, Ke, Kunugi, Keith, Satyamitra, Merriline M., DiCarlo, Andrea L., Winters, Thomas A.

“…Preclinical researchers have long acknowledged the critical need for accurate dosimetry in the conduct of radiation-exposure studies involving living systems…”
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Minimum reporting standards should be expected for preclinical radiobiology irradiators and dosimetry in the published literature by Trompier, François, DeWerd, Larry A, Poirier, Yannick, Dos Santos, Morgane, Sheng, Ke, Kunugi, Keith A, Winters, Thomas A, DiCarlo, Andrea L, Satyamitra, Merriline

“…The cornerstones of science advancement are rigor in performing scientific research, reproducibility of research findings and unbiased reporting of design and…”
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Development of Biomarkers for Radiation Biodosimetry and Medical Countermeasures Research: Current Status, Utility, and Regulatory Pathways by Winters, Thomas A., Taliaferro, Lanyn P., Satyamitra, Merriline M.

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Commonalities Between COVID-19 and Radiation Injury by Rios, Carmen I., Cassatt, David R., Hollingsworth, Brynn A., Satyamitra, Merriline M., Tadesse, Yeabsera S., Taliaferro, Lanyn P., Winters, Thomas A., DiCarlo, Andrea L.

“…As the multi-systemic components of COVID-19 emerge, parallel etiologies can be drawn between SARS-CoV-2 infection and radiation injuries. While some…”
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Acute Radiation Syndrome and the Microbiome: Impact and Review by Hollingsworth, Brynn A., Cassatt, David R., DiCarlo, Andrea L., Rios, Carmen I., Satyamitra, Merriline M., Winters, Thomas A., Taliaferro, Lanyn P.

“…Study of the human microbiota has been a centuries-long endeavor, but since the inception of the National Institutes of Health (NIH) Human Microbiome Project…”
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The NIAID/RNCP Biodosimetry Program: An Overview by Satyamitra, Merriline M, Cassatt, David R, Molinar-Inglis, Olivia, Rios, Carmen I, Taliaferro, Lanyn P, Winters, Thomas A, DiCarlo, Andrea L

“…Established in 2004, the Radiation and Nuclear Countermeasures Program (RNCP), within the National Institute of Allergy and Infectious Diseases (NIAID),…”
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Gastrointestinal Acute Radiation Syndrome: Mechanisms, Models, Markers, and Medical Countermeasures by Winters, Thomas A., Marzella, Libero, Molinar-Inglis, Olivia, Price, Paul W., Han, Nyun Calvin, Cohen, Jonathan E., Wang, Sue-Jane, Fotenos, Anthony F., Sullivan, Julie M., Esker, John I., Lapinskas, Paula J., DiCarlo, Andrea L.

“…There have been a number of reported human exposures to high dose radiation, resulting from accidents at nuclear power plants (e.g., Chernobyl), atomic…”
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Development of Biomarkers for Radiation Biodosimetry and Medical Countermeasures Research: Current Status, Utility, and Regulatory Pathways by Satyamitra, Merriline M., DiCarlo, Andrea L., Hollingsworth, Brynn A., Winters, Thomas A., Taliaferro, Lanyn P.

“…Biomarkers are important indicators of biological processes in health or disease. For this reason, they play a critical role in advanced development of…”
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Considerations of Medical Preparedness to Assess and Treat Various Populations During a Radiation Public Health Emergency by Winters, Thomas A., Cassatt, David R., Harrison-Peters, Jenna R., Hollingsworth, Brynn A., Rios, Carmen I., Satyamitra, Merriline M., Taliaferro, Lanyn P., DiCarlo, Andrea L.

“…During a radiological or nuclear public health emergency, given the heterogeneity of civilian populations, it is incumbent on medical response planners to…”
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Immune Dysfunction from Radiation Exposure by Hollingsworth, Brynn A., Aldrich, Jennifer T., Case, Cullen M., DiCarlo, Andrea L., Hoffman, Corey M., Jakubowski, Ann A., Liu, Qian, Loelius, Shannon G., PrabhuDas, Mercy, Winters, Thomas A., Cassatt, David R.

“…The hematopoietic system is highly sensitive to ionizing radiation. Damage to the immune system may result in opportunistic infections and hemorrhage, which…”
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Advanced Technologies in Radiation Research by Rios, Carmen I., DiCarlo, Andrea L., Harrison, Lynn, Prasanna, Pataje G. S., Buchsbaum, Jeffrey C., Rudokas, Michael W., Gomes, Lauren, Winters, Thomas A.

“…The U.S. Government is committed to maintaining a robust research program that supports a portfolio of scientific experts who are investigating the biological…”
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Radiation-induced multi-organ injury by Molinar-Inglis, Olivia, DiCarlo, Andrea L, Lapinskas, Paula J, Rios, Carmen I, Satyamitra, Merriline M, Silverman, Toby A, Winters, Thomas A, Cassatt, David R

“…Natural history studies have been informative in dissecting radiation injury, isolating its effects, and compartmentalizing injury based on the extent of…”
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Update on Managing the Risks of Exposure to Lentiviral and Retroviral Vectors by Fujimoto, Gary R, Wooley, Dawn P, Byers, Karen B, Yang, Otto O, Behrman, Amy J, Winters, Thomas H, Hudson, T Warner

“…This paper aims to review the risks associated with using lentiviral and retroviral vectors in research and clinical settings and to propose an update to an…”
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Animal Care in Radiation Medical Countermeasures Studies by Rios, Carmen I., Hollingsworth, Brynn A., DiCarlo, Andrea L., Esker, John E., Satyamitra, Merriline M., Silverman, Toby A., Winters, Thomas A., Taliaferro, Lanyn P.

“…Animal models are necessary to demonstrate the efficacy of medical countermeasures (MCM) to mitigate/treat acute radiation syndrome and the delayed effects of…”
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Therapeutic and space radiation exposure of mouse brain causes impaired DNA repair response and premature senescence by chronic oxidant production by Suman, Shubhankar, Rodriguez, Olga C, Winters, Thomas A, Fornace, Jr, Albert J, Albanese, Chris, Datta, Kamal

“…Despite recent epidemiological evidences linking radiation exposure and a number of human ailments including cancer, mechanistic understanding of how radiation…”
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Impact of environmental microbiota on human microbiota of workers in academic mouse research facilities: An observational study by Lai, Peggy S, Allen, Joseph G, Hutchinson, Diane S, Ajami, Nadim J, Petrosino, Joseph F, Winters, Thomas, Hug, Christopher, Wartenberg, Gary R, Vallarino, Jose, Christiani, David C

“…To characterize the microbial environment of workers in academic mouse research facilities using endotoxin, 16S qPCR, and 16S amplicon sequencing. To determine…”
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Radiation-generated Short DNA Fragments May Perturb Non-homologous End-joining and Induce Genomic Instability by Pang, Dalong, Winters, Thomas A, Jung, Mira, Purkayastha, Shubhadeep, Cavalli, Luciane R, Chasovkikh, Sergey, Haddad, Bassem R, Dritschilo, Anatoly

“…Cells exposed to densely ionizing radiation (high-LET) experience more severe biological damage than do cells exposed to sparsely ionizing radiation (low-LET)…”
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Antitumor activity and pharmacokinetic properties of PF-00299804, a second-generation irreversible pan-erbB receptor tyrosine kinase inhibitor by Gonzales, Andrea J, Hook, Kenneth E, Althaus, Irene W, Ellis, Paul A, Trachet, Erin, Delaney, Amy M, Harvey, Patricia J, Ellis, Teresa A, Amato, Danielle M, Nelson, James M, Fry, David W, Zhu, Tong, Loi, Cho-Ming, Fakhoury, Stephen A, Schlosser, Kevin M, Sexton, Karen E, Winters, R Thomas, Reed, Jessica E, Bridges, Alex J, Lettiere, Daniel J, Baker, Deborah A, Yang, Jianxin, Lee, Helen T, Tecle, Haile, Vincent, Patrick W

“…Signaling through the erbB receptor family of tyrosine kinases contributes to the proliferation, differentiation, migration, and survival of a variety of cell…”
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