Search Results - "Thomas‐Virnig, Christina"
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Nonviral human beta defensin-3 expression in a bioengineered human skin tissue: A therapeutic alternative for infected wounds
Published in Wound repair and regeneration (01-05-2012)“…The innate immune system differentially regulates the expression of host defense peptides to combat infection during wound healing. We enhanced the expression…”
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Oxygen deprivation inhibits basal keratinocyte proliferation in a model of human skin and induces regio-specific changes in the distribution of epidermal adherens junction proteins, aquaporin-3, and glycogen
Published in Wound repair and regeneration (01-07-2009)“…ABSTRACT It is generally accepted that hypoxia and recovery from oxygen deprivation contribute to the breakdown and ulceration of human skin. The effects of…”
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Cytokinesis is not controlled by calmodulin or myosin light chain kinase in the Caenorhabditis elegans early embryo
Published in FEBS letters (04-09-2007)“…Furrow ingression in animal cell cytokinesis is controlled by phosphorylation of myosin II regulatory light chain (mRLC). In Caenorhabditis elegans embryos,…”
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TCDD induces dermal accumulation of keratinocyte-derived matrix metalloproteinase-10 in an organotypic model of human skin
Published in Toxicology and applied pharmacology (01-05-2014)“…The epidermis of skin is the first line of defense against the environment. A three dimensional model of human skin was used to investigate tissue-specific…”
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Inhibition of Multidrug-resistant Acinetobacter baumannii by Nonviral Expression of hCAP-18 in a Bioengineered Human Skin Tissue
Published in Molecular therapy (01-03-2009)“…When skin is compromised, a cascade of signals initiates the rapid repair of the epidermis to prevent fluid loss and provide defense against invading microbes…”
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Zygotic loss of ZEN‐4/MKLP1 results in disruption of epidermal morphogenesis in the C. elegans embryo
Published in Developmental dynamics (01-03-2008)“…ZEN‐4/MKLP1 is required maternally for cytokinesis in Caenorhabditis elegans, but was originally identified in a screen for zygotic lethal, enclosure abnormal…”
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The Inositol 1,4,5-Trisphosphate Receptor Regulates Epidermal Cell Migration in Caenorhabditis elegans
Published in Current biology (26-10-2004)“…Polarized migration and spreading of epithelial sheets is important during many processes in vivo, including embryogenesis and wound healing. However, the…”
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Phase I/II Clinical Evaluation of StrataGraft: A Consistent, Pathogen-Free Human Skin Substitute
Published in The journal of trauma (01-03-2009)“…BACKGROUND:Large wounds often require temporary allograft placement to optimize the wound bed and prevent infection until permanent closure is feasible. We…”
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Assessment of Low Vision Referrals before and after Establishment of a Low Vision Program at an Academic Medical Center
Published in Optometry and vision science (01-12-2022)“…We assessed the number of referrals for low vision (LV) services to determine if establishing an LV program at a large academic medical center impacted…”
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Classical human epidermal keratinocyte cell culture
Published in Methods in molecular biology (Clifton, N.J.) (2013)“…It has been more than 30 years since the serial cultivation of human keratinocytes in monolayer culture was first described by Rheinwald and Green. Initially,…”
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Journal Article -
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Non-viral human beta defensin-3 expression in a bioengineered human skin tissue: a therapeutic alternative for infected wounds
Published in Wound repair and regeneration (01-05-2012)“…The innate immune system differentially regulates the expression of host defense peptides to combat infection during wound healing. We enhanced the expression…”
Get full text
Journal Article -
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TCDD induces dermal accumulation of keratinocyte-derived matrix metalloproteinase-10 in an organotypic model of human skin
Published in Toxicology letters (13-09-2009)Get full text
Journal Article -
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Characterization of three mutants implicated in the process of ventral enclosure in Caenorhabditis elegans
Published 01-01-2003“…The migration of epithelial sheets is critical during development and wound healing. However, little is known about the signaling pathways that regulate…”
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Dissertation -
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