Search Results - "Thomas, Sanjeev"

Mitochondrial dysfunction in cognitive neurodevelopmental disorders: Cause or effect? by Anitha, Ayyappan, Thanseem, Ismail, Iype, Mary, Thomas, Sanjeev V.

“…•Mitochondria-mediated energy homeostasis is crucial for brain functions and cognition.•Aberrant mitophagy, respiratory chain deficits, and oxidative stress…”
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Malformation risk of antiepileptic drug exposure during pregnancy in women with epilepsy: Results from a pregnancy registry in South India by Thomas, Sanjeev V., Jose, Manna, Divakaran, Srividya, Sankara Sarma, Prabhakaran

“…Summary Objective Kerala Registry of Epilepsy and Pregnancy had been prospectively evaluating the reproductive issues of women with epilepsy since April 1998…”
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Mucormycosis in COVID-19 patients: predisposing factors, prevention and management by Rudrabhatla, Pavan Kumar, Reghukumar, Aravind, Thomas, Sanjeev V.

“…India is considered the diabetes capital of the world and has the highest burden of mucormycosis. Bacterial, viral and fungal co-infections are increasingly…”
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Grid-Based Preconception Counseling Can Facilitate Shared Decision Making for Women with Epilepsy by Thomas, Sanjeev

“…Women with epilepsy (WWE) and their care providers are equally concerned about the risk of seizures and adverse effects of using antiepileptic drugs (AED)…”
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Management of epilepsy in pregnancy: a report from the International League Against Epilepsy Task Force on Women and Pregnancy by Tomson, Torbjörn, Battino, Dina, Bromley, Rebecca, Kochen, Silvia, Meador, Kimford, Pennell, Page, Thomas, Sanjeev V.

“…ABSTRACT The risks associated with use of antiepileptic drugs during pregnancy are a major concern for all women with epilepsy with childbearing potential…”
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Valproate usage in pregnancy: An audit from the Kerala Registry of Epilepsy and Pregnancy by Seshachala, Balaji B., Jose, Manna, Lathikakumari, Arya M., Murali, Sruthy, Kumar, Arjun S., Thomas, Sanjeev V.

“…Summary Objective This is an audit of the use of valproate (VPA) during pregnancy in women with epilepsy (WWE). Methods We identified all pregnancies exposed…”
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Do Spike Domain Analysis Interictally Correlate With the Ictal Patterns in Temporal Lobe Epilepsy? by Radhakrishnan, Ashalatha, Parameswaran, Sajeesh, Chandran, Anuvitha, Unnithan, Gopeekrishnan, Menon, Ramshekhar N., Cherian, Ajith, Thomas, Sanjeev V.

“…PURPOSE:To study if one can conceptualize the scalp ictal onset pattern through analysis of interictal spike domain analysis in temporal lobe epilepsy (TLE)…”
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Predictors of seizures during pregnancy in women with epilepsy by Thomas, Sanjeev V., Syam, Unnikrishnan, Devi, J. Sucharitha

“…Summary We aimed to characterize the seizure pattern during pregnancy in a large cohort of women with epilepsy (WWE) and identify possible predictors of…”
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Malformation risk of new anti-epileptic drugs in women with epilepsy; observational data from the Kerala registry of epilepsy and pregnancy (KREP) by Thomas, Sanjeev V, Jeemon, Panniyammakal, Pillai, Rajit, Jose, Manna, Lalithakumari, Arya M, Murali, Sruthy, Sanalkumar, Arjun, Salini, Reshma A, Pavithran, Veena

“…•Polytherapy with high-dose valproate during first trimester of pregnancy is associated with higher incidence of malformation in infants.•Lamotrigine…”
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Do women with epilepsy benefit from epilepsy specific pre-conception care? by Baishya, Jitupam, Jose, Manna, A S, Reshma, Sarma, Prabhakaran Sankara, Thomas, Sanjeev V.

“…•Preconception care (PCC) significantly increases peri-pregnancy folate usage and seizure freedom during pregnancy.•PCC does not seem to reduce to occurrence…”
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Neurological illness in pregnancy: Principles and practice by Thomas, Sanjeev

“…The incidence of a variety of neurological disorders, clinical profile, complication pattern and choice of therapy are greatly influenced by the sex of the…”
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Metabolic Effects of Anti-Seizure Medications: A Time to Reevaluate Risks? by Asranna, Ajay, Thomas, Sanjeev

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Genotype-phenotype correlates of infantile-onset developmental & epileptic encephalopathy syndromes in South India: A single centre experience by Mitta, Nandini, Menon, Ramshekhar N, McTague, Amy, Radhakrishnan, Ashalatha, Sundaram, Soumya, Cherian, Ajith, Madhavilatha, GK, Mannan, Ashraf U, Nampoothiri, Sheela, Thomas, Sanjeev V

“…•Indian study on yield of pathogenic/likely pathogenic genetic variants in DEE.•Yield of 31.7 % in DEE comparable to Western literature.•More than 80 % of DEE…”
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Anti-epileptic drug and folic acid usage during pregnancy, seizure and malformation outcomes: Changes over two decades in the Kerala Registry of Epilepsy and Pregnancy by Keni, Ravish R., Jose, Manna, A.S., Reshma, Baishya, Jitupam, Sankara Sarma, Prabhakaran, Thomas, Sanjeev V.

“…•Seizure control during pregnancy and high dose folic acid usage had increased over two decades.•Malformation risk remained unchanged.•Due to use of…”
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Withdrawal of valproic acid treatment during pregnancy and seizure outcome: Observations from EURAP by Tomson, Torbjörn, Battino, Dina, Bonizzoni, Erminio, Craig, John, Lindhout, Dick, Perucca, Emilio, Sabers, Anne, Thomas, Sanjeev V, Vajda, Frank

“…Summary Based on data from the EURAP observational International registry of antiepileptic drugs (AEDs) and pregnancy, we assessed changes in seizure control…”
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Executive Summary: Management of epilepsy in pregnancy: A report from the International League Against Epilepsy Task Force on Women and Pregnancy by Tomson, Torbjörn, Battino, Dina, Bromley, Rebecca, Kochen, Silvia, Meador, Kimford, Pennell, Page, Thomas, Sanjeev V.

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Rare Pathogenic Variants Identified in Whole Exome Sequencing of Monozygotic Twins With Autism Spectrum Disorder by Anitha, Ayyappan, Banerjee, Moinak, Thanseem, Ismail, Prakash, Anil, Melempatt, Nisha, Sumitha, P.S., Iype, Mary, Thomas, Sanjeev V.

“…Autism spectrum disorder (ASD) is a childhood-onset complex neurodevelopmental disorder characterized by problems with communication and social interaction and…”
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Language, intelligence, and educational outcomes of adolescents with antenatal exposure to antiseizure medications: Prospective data from the Kerala Registry of epilepsy and pregnancy by Thomas, Sanjeev V, Salim, Salma, Jacob, Nikita Susan, Jose, Manna, Salini, Reshma A, Selvaraj, Sajith, Gomez, Treasa Stemy, Sreedharan, Hema, Jeemon, Panniyammakal

“…OBJECTIVEIn a prospective cohort of children (13-21 years) of women with epilepsy (CWWE), we compared those exposed to antiseizure medications (ASM) in utero…”
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Seizure outcome and its predictors after frontal lobe epilepsy surgery by Samuel P, Joseph, Menon, Ramshekhar N., Chandran, Anuvitha, Thomas, Sanjeev V., Vilanilam, George, Abraham, Mathew, Radhakrishnan, Ashalatha

“…Objectives Frontal lobe epilepsy (FLE) surgery is the second most common focal resective surgery for drug‐resistant epilepsy. Not many studies are available…”
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Enduring language deficits in children of women with epilepsy and the potential role of intrauterine exposure to antiepileptic drugs by Unnikrishnan, Gopikrishnan, Jacob, Nikita Susan, Salim, Salma, Jose, Manna, Salini, Reshma A., Pavithran, Veena, Jeemon, Panniyammakal, Thomas, Sanjeev V.

“…Objective Exposure to certain intrauterine antiepileptic drugs (AEDs) can negatively influence the language skills and intelligence of young children. It…”
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