Search Results - "Thomas, S R"

Combining human liver ECM with topographically featured electrospun scaffolds for engineering hepatic microenvironment by Gao, Yunxi, Gadd, Victoria L., Heim, Maria, Grant, Rhiannon, Bate, Thomas S. R., Esser, Hannah, Gonzalez, Sofia Ferreira, Man, Tak Yung, Forbes, Stuart J., Callanan, Anthony

“…Liver disease cases are rapidly expanding worldwide, and transplantation remains the only effective cure for end-stage disease. There is an increasing demand…”
Get full text

PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling by Moody, S E, Schinzel, A C, Singh, S, Izzo, F, Strickland, M R, Luo, L, Thomas, S R, Boehm, J S, Kim, S Y, Wang, Z C, Hahn, W C

“…Targeting HER2 with antibodies or small molecule inhibitors in HER2-positive breast cancer leads to improved survival, but resistance is a common clinical…”
Get full text

Response differences of HepG2 and Primary Mouse Hepatocytes to morphological changes in electrospun PCL scaffolds by Bate, Thomas S. R., Gadd, Victoria L., Forbes, Stuart J., Callanan, Anthony

“…Liver disease cases are rapidly expanding across the globe and the only effective cure for end-stage disease is a transplant. Transplant procedures are costly…”
Get full text

Lightning as a space-weather hazard: UK thunderstorm activity modulated by the passage of the heliospheric current sheet by Owens, M. J., Scott, C. J., Bennett, A. J., Thomas, S. R., Lockwood, M., Harrison, R. G., Lam, M. M.

“…Lightning flash rates, RL, are modulated by corotating interaction regions (CIRs) and the polarity of the heliospheric magnetic field (HMF) in near‐Earth…”
Get full text

The 22-Year Hale Cycle in Cosmic Ray Flux – Evidence for Direct Heliospheric Modulation by Thomas, S. R., Owens, M. J., Lockwood, M.

“…The ability to predict times of greater galactic cosmic ray (GCR) fluxes is important for reducing the hazards caused by these particles to satellite…”
Get full text

A review of long-term outcomes for late presenting developmental hip dysplasia by Thomas, S R Y W

“…Successful management of late presenting hip dislocation in childhood is judged by the outcome not just at skeletal maturity but well beyond into adulthood and…”
Get full text

Evaluation of androgen assay results using a curated Hershberger database by Kleinstreuer, N.C., Browne, P., Chang, X., Judson, R., Casey, W., Ceger, P., Deisenroth, C., Baker, N., Markey, K., Thomas, R.S.

“…[Display omitted] •We used 39 reference chemicals with reproducible AR pathway effects in rodents to evaluate the ToxCast/Tox 21 AR model based on 11 in vitro…”
Get full text

The DEAD-box protein p72 regulates ERα- oestrogen-dependent transcription and cell growth, and is associated with improved survival in ERα-positive breast cancer by Wortham, N C, Ahamed, E, Nicol, S M, Thomas, R S, Periyasamy, M, Jiang, J, Ochocka, A M, Shousha, S, Huson, L, Bray, S E, Coombes, R C, Ali, S, Fuller-Pace, F V

“…The DEAD-box RNA helicases p68 (DDX5) and p72 (DDX17) have been shown to act as transcriptional co-activators for a diverse range of transcription factors,…”
Get full text

Development of a curated Hershberger database by Browne, P., Kleinstreuer, N.C., Ceger, P., Deisenroth, C., Baker, N., Markey, K., Thomas, R.S., Judson, R.J., Casey, W.

“…[Display omitted] •A systematic literature review was conducted to identify Hershberger assays testing in vivo (anti)androgens effects of chemicals.•Details on…”
Get full text

Galactic Cosmic Ray Modulation near the Heliospheric Current Sheet by Thomas, S. R., Owens, M. J., Lockwood, M., Scott, C. J.

“…Galactic cosmic rays (GCRs) are modulated by the heliospheric magnetic field (HMF) both over decadal time scales (due to long-term, global HMF variations), and…”
Get full text

Voluntary feed intake and growth performance of slow-growing pigs fed on increasing levels of ensiled potato hash meal by Ncobela, C. N, Kanengoni, A. T, Thomas, R. S, Chimonyo, M.

“…The objective of the study was to determine voluntary feed intake and growth performance of Windsnyer pigs fed on increasing levels of potato hash silage meal…”
Get full text

Hypoxia regulates the production and activity of glucose transporter-1 and indoleamine 2,3-dioxygenase in monocyte-derived endothelial-like cells: possible relevance to infantile haemangioma pathogenesis by Herbert, A., Ng, H., Jessup, W., Kockx, M., Cartland, S., Thomas, S.R., Hogg, P.J., Wargon, O.

“…Summary Background  Infantile haemangioma (IH) may present as a precursor area of pallor prior to the initial proliferative phase, which implies that the early…”
Get full text

MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation by Huang, Y, Thoms, J A I, Tursky, M L, Knezevic, K, Beck, D, Chandrakanthan, V, Suryani, S, Olivier, J, Boulton, A, Glaros, E N, Thomas, S R, Lock, R B, MacKenzie, K L, Bushweller, J H, Wong, J W H, Pimanda, J E

“…Aberrant ERG (v-ets avian erythroblastosis virus E26 oncogene homolog) expression drives leukemic transformation in mice and high expression is associated with…”
Get full text

Use of the Entero-Test, a Novel Approach for the Noninvasive Capture of Biliary Metabolites in Dogs by GUINEY, W. J, BEAUMONT, C, THOMAS, S. R

“…Preclinical information on the biliary metabolites of a drug candidate is typically obtained through the collection of bile after surgical cannulation of the…”
Get full text

Long-term outcome after anterolateral open reduction and Salter osteotomy for late presenting developmental dysplasia of the hip by Thomas, S. R. Y. W.

“…Introduction Only a handful of studies report outcomes after open reduction for developmental hip dislocation beyond skeletal maturity. For successfully…”
Get full text

Prey detection through olfaction by the soil-dwelling larvae of the carabid predator Pterostichus melanarius by Thomas, R.S., Glen, D.M., Symondson, W.O.C.

“…Immunological and behavioural studies have shown that adult carabids such as Pterostichus melanarius (Illiger) are predators of slugs. However, little is known…”
Get full text

Gene Expression Changes Following Acute Hydrogen Sulfide (H2S)-induced Nasal Respiratory Epithelial Injury by Roberts, E. S., Thomas, R. S., Dorman, D. C.

“…Hydrogen sulfide (H2S) is a naturally occurring gas that is also associated with several industries. The potential for widespread human inhalation exposure to…”
Get full text

Helicobacter pylori Uptake and Efflux: Basis for Intrinsic Susceptibility to Antibiotics In Vitro by Bina, J. E, Alm, R. A, Uria-Nickelsen, M, Thomas, S. R, Trust, T. J, Hancock, R. E. W

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Identification of toxicologically predictive gene sets using cDNA microarrays by Thomas, R S, Rank, D R, Penn, S G, Zastrow, G M, Hayes, K R, Pande, K, Glover, E, Silander, T, Craven, M W, Reddy, J K, Jovanovich, S B, Bradfield, C A

“…We have developed an approach to classify toxicants based upon their influence on profiles of mRNA transcripts. Changes in liver gene expression were examined…”
Get more information

A Unification of Nanotopography and Extracellular Matrix in Electrospun Scaffolds for Bioengineered Hepatic Models by Gao, Yunxi, Bate, Thomas S. R., Callanan, Anthony

“…Donor liver shortage is a crucial global public health problem as whole-organ transplantation is the only definitive cure for liver disease. Liver tissue…”
Get full text