Search Results - "Thomas, S H L"

Synthetic cannabinoid receptor agonists: classification and nomenclature by Potts, A. J., Cano, C., Thomas, S. H. L., Hill, S. L.

“…Introduction: The emergence of novel psychoactive substances has changed the epidemiology of drugs used recreationally throughout Europe and have posed…”
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Thioridazine and sudden unexplained death in psychiatric in-patients by Reilly, J. G., Ayis, S. A., Ferrier, I. N., Jones, S. J., Thomas, S. H. L.

“…Sudden death has been linked to antipsychotic therapy, but the relative risk associated with specific drugs is unknown. To assess the risk of sudden…”
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Clinical characteristics of mephedrone toxicity reported to the U.K. National Poisons Information Service by James, D, Adams, R D, Spears, R, Cooper, G, Lupton, D J, Thompson, J P, Thomas, S H L

“…To describe the patterns and clinical features of toxicity related to recreational use of mephedrone and other cathinones in the U.K. using data collected by…”
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Safety of sertindole versus risperidone in schizophrenia: principal results of the sertindole cohort prospective study (SCoP) by Thomas, S. H. L., Drici, M. D., Hall, G. C., Crocq, M. A., Everitt, B., Lader, M. H., Jeunne, C. Le, Naber, D., Priori, S., Sturkenboom, M., Thibaut, F., Peuskens, J., Mittoux, A., Tanghøj, P., Toumi, M., Moore, N. D., Mann, R. D.

“…Thomas SHL, Drici MD, Hall GC, Crocq MA, Everitt B, Lader MH, Le Jeunne C, Naber D, Priori S, Sturkenboom M, Thibaut F, Peuskens J, Mittoux A, Tanghøj P, Toumi…”
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Factors Affecting Drug Concentrations and QT Interval During Thioridazine Therapy by Thanacoody, R H K, Daly, A K, Reilly, J G, Ferrier, I N, Thomas, S H L

“…The objective of this study was to investigate factors affecting steady‐state plasma concentrations of thioridazine. A cross‐sectional study of patients…”
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Effectiveness of delayed activated charcoal administration in simulated paracetamol (acetaminophen) overdose by Yeates, P. J. A., Thomas, S. H. L.

“…Aims Oral activated charcoal is used to treat drug overdose and is effective at reducing drug absorption when administered within 1 h of drug ingestion. There…”
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Severe toxicity involving N-pyrrolidino etonitazene in the United Kingdom-a case report by Pucci, M., Hudson, S., Hill, S. L., Thomas, S. H. L.

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Liver unit admission following paracetamol overdose with concentrations below current UK treatment thresholds by Beer, C., Pakravan, N., Hudson, M., Smith, L.T., Simpson, K., Bateman, D.N., Thomas, S.H.L.

“…Background: It has been suggested that current UK thresholds for treating paracetamol overdose should be reduced, following case reports of patients developing…”
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Comparison of the Effects of Thioridazine and Mesoridazine on the QT Interval in Healthy Adults After Single Oral Doses by Salih, I S M, Thanacoody, R H K, McKay, G A, Thomas, S H L

“…We compared the effects of single doses of thioridazine and mesoridazine on the heart rate‐corrected QT (QTc) interval in healthy adult volunteers. QTc…”
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Anti‐TNF agents for rheumatoid arthritis by Seymour, H. E., Worsley, A., Smith, J. M., Thomas, S. H. L.

“…Rheumatoid arthritis (RA) is a chronic inflammatory, autoimmune disease with a prevalence of approximately 1% and an annual incidence of 0.04%. Up to 50% of…”
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Toxicoepidemiology and predictors of death in 2,4-dinitrophenol (DNP) toxicity by Potts, A. J., Bowman, N. J., Seger, D. L., Thomas, S. H. L.

“…2,4-Dinitrophenol (DNP) is a highly toxic industrial chemical that is sometimes misused to reduce body fat. Toxicity following ingestion of DNP has recently…”
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Clinical features associated with ADB-BUTINACA exposure in patients attending emergency departments in England by King, A., Hill, S. L., Pucci, M., Bailey, G., Keating, L., Macfarlane, R., Cantle, F., Hudson, S., Thomas, S. H. L.

“…Synthetic cannabinoid receptor agonists (SCRA) are commonly encountered new psychoactive substances. Here we report the recent detection of ADB-BUTINACA in…”
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Pregnancy outcomes following maternal venlafaxine use: A prospective observational comparative cohort study by Richardson, J.L., Martin, F., Dunstan, H., Greenall, A., Stephens, S., Yates, L.M., Thomas, S.H.L.

“…•No statistically significant differences in the hazard of spontaneous abortion was observed following gestational venlafaxine use compared with either…”
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Pregnancy outcomes after maternal varenicline use; analysis of surveillance data collected by the European Network of Teratology Information Services by Richardson, J.L., Stephens, S., Yates, L.M., Diav-Citrin, O., Arnon, J., Beghin, D., Kayser, A., Kennedy, D., Cupitt, D., te Winkel, B., Peltonen, M., Kaplan, Y.C., Thomas, S.H.L.

“…•This study provides no signal that varenicline is a major human teratogen.•Varenicline exposed major congenital malformation rate (2.25%).•Rate is considered…”
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A case control study to examine the pharmacological factors underlying ventricular septal defects in the North of England by BATEMAN, D. N, MCELHATTON, P. R, DICKINSON, D, WREN, C, MATTHEWS, J. N. S, O'KEEFFE, M, THOMAS, S. H. L

“…Amphetamine exposure is associated with congenital cardiac abnormalities in animals. We previously reported an association between recreational use of…”
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Effect of the UK Psychoactive Substances Act 2016 on episodes of toxicity related to new psychoactive substances as reported to the National Poisons Information Service. A time series analysis by Al-Banaa, I., Hawkins, L., Hill, S.L., Lupton, D.J., Jackson, G., Sandilands, E.A., Bradberry, S.M., Thompson, J.P., Rushton, S., Thomas, S.H.L.

“…Background: There have been recent increases in use of new psychoactive substances (NPS) associated with acute health harms including hospital presentations…”
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Pregnancy outcome following maternal use of zanamivir or oseltamivir during the 2009 influenza A/H1N1 pandemic: a national prospective surveillance study by Dunstan, HJ, Mill, AC, Stephens, S, Yates, LM, Thomas, SHL

“…Objective To conduct enhanced surveillance for signals of teratogenesis following use of the neuraminidase inhibitors zanamivir and oseltamivir in the…”
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Sensitivity of the UK Clinical Practice Research Datalink to Detect Neurodevelopmental Effects of Medicine Exposure in Utero: Comparative Analysis of an Antiepileptic Drug-Exposed Cohort by Charlton, R. A., McGrogan, A., Snowball, J., Yates, L. M., Wood, A., Clayton-Smith, J., Smithson, W. H., Richardson, J. L., McHugh, N., Thomas, S. H. L., Baker, G. A., Bromley, R.

“…Introduction Electronic healthcare data have several advantages over prospective observational studies, but the sensitivity of data on neurodevelopmental…”
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QTc-interval abnormalities and psychotropic drug therapy in psychiatric patients by Reilly, JG, Ayis, SA, Ferrier, IN, Jones, SJ, Thomas, SHL

“…Sudden unexplained death in psychiatric patients may be due to drug-induced arrhythmia, of which lengthening of the rate-corrected QT interval (QTc) on the…”
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Using poisons information service data to assess the acute harms associated with novel psychoactive substances by Wood, D. M., Hill, S. L., Thomas, S. H. L., Dargan, P. I.

“…Novel psychoactive substances (NPS) can cause significant acute toxicity but usually little is known about their toxicity when they enter the recreational drug…”
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