Search Results - "Thomas, Rintu"
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1
Rethink of EGFR in Cancer With Its Kinase Independent Function on Board
Published in Frontiers in oncology (23-08-2019)“…The epidermal growth factor receptor (EGFR) is one of most potent oncogenes that are commonly altered in cancers. As a receptor tyrosine kinase, EGFR's kinase…”
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Journal Article -
2
ELF3 mediates IL‐1α induced differentiation of mesenchymal stem cells to inflammatory iCAFs
Published in Stem cells (Dayton, Ohio) (01-12-2021)“…Stromal cells in the tumor microenvironment regulate the immune landscape and tumor progression. Yet, the ontogeny and heterogeneity of reactive stromal cells…”
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Journal Article -
3
Kinase-Inactivated EGFR Is Required for the Survival of Wild-Type EGFR-Expressing Cancer Cells Treated with Tyrosine Kinase Inhibitors
Published in International journal of molecular sciences (22-05-2019)“…Inhibiting the tyrosine kinase activity of epidermal growth factor receptor (EGFR) using small molecule tyrosine kinase inhibitors (TKIs) is often ineffective…”
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Journal Article -
4
Perceived stress and eating behavior among professional and nonprofessional undergraduate students in Udupi District, Karnataka
Published in Indian journal of public health (01-10-2019)“…Background: Stress is an unavoidable part of our life. Certain amount of stress is needed for our survival. Stress is one of the factors, which affects the…”
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Journal Article -
5
Androgen receptor variant-7 regulation by tenascin-c induced src activation
Published in Cell communication and signaling (10-08-2022)“…Bone metastatic prostate cancer does not completely respond to androgen-targeted therapy and generally evolves into lethal castration resistant prostate cancer…”
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Journal Article -
6
Targeted reduction of the EGFR protein, but not inhibition of its kinase activity, induces mitophagy and death of cancer cells through activation of mTORC2 and Akt
Published in Oncogenesis (New York, NY) (23-01-2018)“…The oncogenic epidermal growth factor receptor (EGFR) is commonly overexpressed in solid cancers. The tyrosine kinase activity of EGFR has been a major…”
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Journal Article -
7
Two-Dimensional Fluorescence Difference Spectroscopy of ZnO and Mg Composites in the Detection of Physiological Protein and RNA Interactions
Published in Materials (15-12-2017)“…Two-dimensional fluorescence difference spectroscopy (2-D FDS) was used to determine the unique spectral signatures of zinc oxide (ZnO), magnesium oxide (MgO),…”
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Journal Article -
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Abstract A021: Reactive osteogenic-niche regulation of endocrine resistance in prostate cancer bone metastases: Role of tenascin-C induced metabolic shift in regulating therapeutic resistance in prostate cancer
Published in Cancer research (Chicago, Ill.) (02-06-2023)“…Abstract Background: The main objective of the study is to investigate the regulatory role of reactive osteogenic niche in evolution of therapeutic resistance…”
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Journal Article -
9
The Role of Kinase Inactive EGFR in Cancer Cell Survival
Published 01-01-2019“…Inhibiting the tyrosine kinase activity of epidermal growth factor receptor (EGFR) using small molecule tyrosine kinase inhibitors (TKIs) are often ineffective…”
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Dissertation -
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Detection and segmentation of mitotic cell nuclei in breast histopathology images
Published in 2017 International Conference on Networks & Advances in Computational Technologies (NetACT) (01-07-2017)“…Detection and segmentation of cells is an important step for classifying the cells as cancerous or non-cancerous. Pathologists use microscopic images for…”
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Conference Proceeding -
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A review on cell detection and segmentation in microscopic images
Published in 2017 International Conference on Circuit ,Power and Computing Technologies (ICCPCT) (01-04-2017)“…Image analysis of cells and tissues is an important area of research, since it forms a basis for large number of biomedical applications. Many complexities…”
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Conference Proceeding -
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Photoplethysmogram (PPG) signal analysis and wavelet de-noising
Published in 2014 Annual International Conference on Emerging Research Areas: Magnetics, Machines and Drives (AICERA/iCMMD) (01-07-2014)“…The use of optical sensors is nowadays very common in the area of non-invasive diagnosis. This is mainly because of their salient features like, simple…”
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Conference Proceeding -
13
Filter design for MIMO Gaussian wiretap channel
Published in 2014 Annual International Conference on Emerging Research Areas: Magnetics, Machines and Drives (AICERA/iCMMD) (01-07-2014)“…In wireless communication, the broadcast nature of the medium has made information security a very important concern. This nature allows the unauthorized…”
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Conference Proceeding -
14
Generation of colon tissue graph for identifying deformed images
Published in 2014 Annual International Conference on Emerging Research Areas: Magnetics, Machines and Drives (AICERA/iCMMD) (01-07-2014)“…Cell is the basic functional unit of an organism. The cells together form a tissue and tissues together form an organ. Cancer causes the cells in an area to…”
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Conference Proceeding