Search Results - "Thomas, Nihal"
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Normal Weight Obesity: An Underrecognized Problem in Individuals of South Asian Descent
Published in Clinical therapeutics (01-08-2019)“…AbstractPurposeObesity has attained pandemic proportions across the world, and its prevalence in developing countries is also on the rise. Nevertheless, there…”
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Prevalence of normal weight obesity and its associated cardio-metabolic risk factors – Results from the baseline data of the Kerala Diabetes Prevention Program (KDPP)
Published in PloS one (25-08-2020)“…Background Cardiometabolic disorders are frequently observed among those who have obesity as measured by body mass index (BMI). However, there is limited data…”
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Barker Hypothesis and Hypertension
Published in Frontiers in public health (21-01-2022)“…Early onset hypertension is one of many major medical disorders that have evolved over the current millennium across both the developing as well as the…”
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The impact of air pollution on deaths, disease burden, and life expectancy across the states of India: the Global Burden of Disease Study 2017
Published in The Lancet. Planetary health (01-01-2019)“…Air pollution is a major planetary health risk, with India estimated to have some of the worst levels globally. To inform action at subnational levels in…”
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Multiple Pulmonary Emboli as a Primary Presentation of Renal Cell Carcinoma
Published in Chrismed journal of health and research (01-07-2023)“…A 57-year-old housewife presented with complaints of sudden onset of chest pain and dyspnea. Computed tomography angiography revealed saddle-shaped pulmonary…”
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Understanding the predictive accuracy of the InsuTAG index over other surrogate indices in normoglycaemic, non-obese males from Southern India
Published in Scientific reports (09-11-2023)“…We aimed to evaluate the predictive accuracy of InsuTAG index against M value of the hyperinsulinaemic-Euglycaemic clamp (HEC) procedure and fasting surrogate…”
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Effectiveness of a scalable group-based education and monitoring program, delivered by health workers, to improve control of hypertension in rural India: A cluster randomised controlled trial
Published in PLoS medicine (01-01-2020)“…New methods are required to manage hypertension in resource-poor settings. We hypothesised that a community health worker (CHW)-led group-based education and…”
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Association of serum 25-Hydroxy vitamin D with total and regional adiposity and cardiometabolic traits
Published in PloS one (28-12-2020)“…Lower serum 25-hydroxyvitamin D [25(OH)D] is associated with greater adiposity and adverse cardiometabolic risk profile. The evidence is inconsistent among…”
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Screening for prevalence of current TB disease and latent TB infection in type 2 diabetes mellitus patients attending a diabetic clinic in an Indian tertiary care hospital
Published in PloS one (05-06-2020)“…Diabetes triples the risk of developing tuberculosis (TB). This study was designed to determine the prevalence of past and current TB disease and Latent TB…”
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Maturity onset diabetes of the young in India - a distinctive mutation pattern identified through targeted next-generation sequencing
Published in Clinical endocrinology (Oxford) (01-04-2015)“…Summary Objective To establish and utilize a Next‐Generation Sequencing (NGS)‐based strategy to screen for maturity onset diabetes of the young (MODY) gene…”
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SPINA Carb: a simple mathematical model supporting fast in-vivo estimation of insulin sensitivity and beta cell function
Published in Scientific reports (21-10-2022)“…Modelling insulin-glucose homeostasis may provide novel functional insights. In particular, simple models are clinically useful if they yield diagnostic…”
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Insulin degludec, an ultra-long-acting basal insulin, once a day or three times a week versus insulin glargine once a day in patients with type 2 diabetes: a 16-week, randomised, open-label, phase 2 trial
Published in The Lancet (British edition) (12-03-2011)“…Summary Background Insulin degludec is a new basal insulin that forms soluble multihexamer assemblies after subcutaneous injection, resulting in an ultra-long…”
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Comprehensive evaluation of patterns of hypoglycemia unawareness (HUA) and glycemic variability (GV) in patients with fibrocalculous pancreatic diabetes (FCPD): A cross-sectional study from South India
Published in PloS one (12-07-2022)“…Objectives Hypoglycemia unawareness (HUA) in patients with FCPD is common with an unclear etiology. We evaluated the prevalence, characteristics of HUA,…”
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Congenital Adrenal Hyperplasia - A Comprehensive Review of Genetic Studies on 21-Hydroxylase Deficiency from India
Published in Indian journal of endocrinology and metabolism (01-03-2024)“…Congenital adrenal hyperplasia (CAH) comprises a heterogeneous group of autosomal recessive disorders impairing adrenal steroidogenesis. Most cases are caused…”
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The clinical diversity of primary hypothyroidism presenting as a spontaneous ovarian hyperstimulation syndrome
Published in Endocrinology, diabetes & metabolism case reports (01-07-2024)“…Ovarian hyperstimulation syndrome (OHSS) usually occurs in patients undergoing assisted reproduction techniques and ovulation induction. Its variant,…”
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Evaluation of a training program of hypertension for accredited social health activists (ASHA) in rural India
Published in BMC health services research (02-05-2018)“…Hypertension is a major risk factor for cardiovascular disease, a leading cause of premature death and disability in India. Since access to health services is…”
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A novel simple disposition index (SPINA‐DI) from fasting insulin and glucose concentration as a robust measure of carbohydrate homeostasis
Published in Journal of diabetes (01-09-2024)“…Aims The widely used dynamic disposition index, derived from oral glucose tolerance testing, is an integrative measure of the homeostatic performance of the…”
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The prevalence of vertebral fractures among Indian perimenopausal women and its association with ovarian biomarkers
Published in Journal of bone and mineral metabolism (2022)“…Introduction There is dearth of data on prevalent vertebral fractures in perimenopausal women in India and limited literature on the utility of FSH, AMH and…”
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Comprehensive Maturity Onset Diabetes of the Young (MODY) Gene Screening in Pregnant Women with Diabetes in India
Published in PloS one (01-01-2017)“…Pregnant women with diabetes may have underlying beta cell dysfunction due to mutations/rare variants in genes associated with Maturity Onset Diabetes of the…”
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