Search Results - "Thomas, Michael P."

Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3′ Splice Site Selection through Use of a Different Branch Point by Darman, Rachel B., Seiler, Michael, Agrawal, Anant A., Lim, Kian H., Peng, Shouyong, Aird, Daniel, Bailey, Suzanna L., Bhavsar, Erica B., Chan, Betty, Colla, Simona, Corson, Laura, Feala, Jacob, Fekkes, Peter, Ichikawa, Kana, Keaney, Gregg F., Lee, Linda, Kumar, Pavan, Kunii, Kaiko, MacKenzie, Crystal, Matijevic, Mark, Mizui, Yoshiharu, Myint, Khin, Park, Eun Sun, Puyang, Xiaoling, Selvaraj, Anand, Thomas, Michael P., Tsai, Jennifer, Wang, John Y., Warmuth, Markus, Yang, Hui, Zhu, Ping, Garcia-Manero, Guillermo, Furman, Richard R., Yu, Lihua, Smith, Peter G., Buonamici, Silvia

“…Recurrent mutations in the spliceosome are observed in several human cancers, but their functional and therapeutic significance remains elusive. SF3B1, the…”
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Lumbar Interbody Fusions by Manjila, Sunil V, Mroz, Thomas, Steinmetz, Michael P

“…Authored by experienced surgeons and key innovators in the fast-moving field of LIF surgery, this book provides an in-depth, focused approach to recent…”
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Update on primary PCI for patients with STEMI by Thomas, Michael P., MD, Bates, Eric R., MD

“…Abstract Primary PCI is the dominant reperfusion strategy for patients with ST-elevation myocardial infarction and continues to evolve. The purpose of this…”
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Treatment-Emergent Mutations in NAEβ Confer Resistance to the NEDD8-Activating Enzyme Inhibitor MLN4924 by Milhollen, Michael A., Thomas, Michael P., Narayanan, Usha, Traore, Tary, Riceberg, Jessica, Amidon, Benjamin S., Bence, Neil F., Bolen, Joseph B., Brownell, James, Dick, Lawrence R., Loke, Huay-Keng, McDonald, Alice A., Ma, Jingya, Manfredi, Mark G., Sells, Todd B., Sintchak, Mike D., Yang, Xiaofeng, Xu, Qing, Koenig, Erik M., Gavin, James M., Smith, Peter G.

“…MLN4924 is an investigational small-molecule inhibitor of NEDD8-activating enzyme (NAE) in clinical trials for the treatment of cancer. MLN4924 is a…”
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Post-intensive cardiac care outpatient long-term outreach clinic (PICCOLO clinic): Defining health care needs and outcomes among coronary care unit survivors by Mason, Christopher K., Adie, Sara K., Shea, Michael J., Konerman, Matthew C., Thomas, Michael P., McSparron, Jakob I., Iwashyna, Theodore J., Prescott, Hallie C., Thompson, Andrea D.

“…Patients who survive critical illness endure complex physical and mental health conditions, referred to as post-intensive care syndrome (PICS). The University…”
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Percutaneous Coronary Intervention Utilization and Appropriateness across the United States by Thomas, Michael P, Parzynski, Craig S, Curtis, Jeptha P, Seth, Milan, Nallamothu, Brahmajee K, Chan, Paul S, Spertus, John A, Patel, Manesh R, Bradley, Steven M, Gurm, Hitinder S

“…Substantial geographic variation exists in percutaneous coronary intervention (PCI) use across the United States. It is unclear the extent to which high PCI…”
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When Is it Right to Be Wrong? by Thomas, Michael P., MD, Gurm, Hitinder S., MD, Nallamothu, Brahmajee K., MD, MPH

“…[...]their observation of 10-fold variation in hospital rates of normal coronary arteries is important. [...]this report raises a real concern regarding…”
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Acute Necrotizing Eosinophilic Myocarditis in a Patient Taking Garcinia Cambogia Extract Successfully Treated With High-Dose Corticosteroids by Allen, Scott F., MD, Godley, Robert W., MD, Evron, Joshua M., MD, Heider, Amer, MD, Nicklas, John M., MD, Thomas, Michael P., MD

“…Abstract A previously healthy 48-year-old woman was evaluated for lightheadedness and chest heaviness 2 weeks after starting the herbal supplement Garcinia…”
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Cor Triatriatum: A Reversible Cause of Severe Pulmonary Hypertension by Howe, Michael J., MD, Thomas, Michael P., MD, Agarwal, Prachi P., MD, Bach, David S., MD, Rubenfire, Melvyn, MD

“…Abstract Cor triatriatum sinister is a congenital heart disorder that can lead to progressive dyspnea, pulmonary hypertension, and ultimately right ventricular…”
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Outcome of Contemporary Percutaneous Coronary Intervention in the Elderly and the Very Elderly: Insights From the Blue Cross Blue Shield of Michigan Cardiovascular Consortium by Thomas, Michael P., Moscucci, Mauro, Smith, Dean E., Aronow, Herb, Share, David, Kraft, Phillip, Gurm, Hitinder S.

“…Background: There is a paucity of data on the outcome of contemporary percutaneous coronary intervention (PCI) in the elderly. Accordingly, we assessed the…”
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An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer by Soucy, Teresa A., Smith, Peter G., Milhollen, Michael A., Berger, Allison J., Gavin, James M., Adhikari, Sharmila, Brownell, James E., Burke, Kristine E., Cardin, David P., Critchley, Stephen, Cullis, Courtney A., Doucette, Amanda, Garnsey, James J., Gaulin, Jeffrey L., Gershman, Rachel E., Lublinsky, Anna R., McDonald, Alice, Mizutani, Hirotake, Narayanan, Usha, Olhava, Edward J., Peluso, Stephane, Rezaei, Mansoureh, Sintchak, Michael D., Talreja, Tina, Thomas, Michael P., Traore, Tary, Vyskocil, Stepan, Weatherhead, Gabriel S., Yu, Jie, Zhang, Julie, Dick, Lawrence R., Claiborne, Christopher F., Rolfe, Mark, Bolen, Joseph B., Langston, Steven P.

“…The clinical development of an inhibitor of cellular proteasome function suggests that compounds targeting other components of the ubiquitin–proteasome system…”
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Integration of social media with targeted emails and in‐person outreach for exception from informed consent community consultation by Hsu, Cindy H., Fowler, Jennifer, Cranford, James A., Thomas, Michael P., Neumar, Robert W.

“…Background Exception from informed consent (EFIC) enables the enrollment of research subjects with emergent conditions to clinical trials without prior…”
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Total water management strategies for Utility master planning by JEFFCOAT, STUART, BAUGHMAN, DOUGLAS, THOMAS, P. MICHAEL

“…Increasing demands on water resources and the associated stresses of continued population growth, land‐use changes, and climate uncertainty require water…”
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A quasi-experimental study of a bundled diagnostic stewardship intervention for ventilator-associated pneumonia by Albin, Owen R, Troost, Jonathan P, Saravolatz, 2nd, Louis, Thomas, Michael P, Hyzy, Robert C, Konkle, Mark A, Weirauch, Andrew J, Dickson, Robert P, Rao, Krishna, Kaye, Keith S

“…Diagnostic error in the use of respiratory cultures for ventilator-associated pneumonia (VAP) fuels misdiagnosis and antibiotic overuse within intensive care…”
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Utilization of Cardiac Rehabilitation Among Cardiac Intensive Care Unit Survivors by Sola, Michael, Thompson, Andrea D., Coe, Antoinette B., Marshall, Vincent D., Thomas, Michael P., Prescott, Hallie C., Konerman, Matthew C.

“…Cardiac rehabilitation (CR) is associated with decreased mortality and rehospitalization rates for patients with a variety of cardiac conditions. Although CR…”
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Atypical Antipsychotic Safety in the CICU by Hanna, Matthew P., Adie, Sarah K., Ketcham, Scott W., Deshmukh, Amrish, Gondi, Keerthi, Abdul-Aziz, Ahmad A., Prescott, Hallie C., Thomas, Michael P., Konerman, Matthew C.

“…Atypical antipsychotics are used in cardiac intensive care units (CICU) to treat delirium despite limited data on safety in patients with acute cardiovascular…”
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Characteristics of Heart Failure Patients With or Without Hypotension When Transitioning From Nitroprusside to Sacubitril-Valsartan by Adie, Sarah K., Ketcham, Scott W., Abdul-Aziz, Ahmad A., Thomas, Michael P., Konerman, Matthew C.

“…Sacubitril-valsartan is an angiotensin receptor-neprilysin inhibitor indicated for the treatment of patients with symptomatic heart failure with reduced…”
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Impact of a pharmacist in an interdisciplinary post-cardiac intensive care unit clinic by Adie, Sarah K., Thompson, Amy N., Konerman, Matthew C., Shea, Michael J., Thomas, Michael P., Thompson, Andrea D.

“…The complex needs of cardiac patients shortly after discharge from a cardiac intensive care unit (CICU) provides a unique opportunity for a pharmacist to help…”
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Implementation of a Nurse-Driven Spontaneous Awakening Trial Protocol in a Cardiac Intensive Care Unit by Ketcham, Scott W, Adie, Sarah K, Brummel, Kent, Walker, Emily, Prescott, Hallie C, Thomas, Michael P

“…In patients receiving mechanical ventilation, spontaneous awakening trials reduce morbidity and mortality when paired with spontaneous breathing trials…”
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Percutaneous coronary intervention strategies in patients with ST-segment elevation myocardial infarction and multivessel coronary artery disease by Thomas, Michael P, Bates, Eric R

“…PURPOSE OF REVIEWThis review aims to summarize recent reports on percutaneous coronary intervention (PCI) strategies for patients with ST-elevation myocardial…”
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