Search Results - "Thomas, Münzel"
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Transportation noise pollution and cardiovascular disease
Published in Nature reviews cardiology (01-09-2021)“…Epidemiological studies have found that transportation noise increases the risk of cardiovascular morbidity and mortality, with high-quality evidence for…”
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Effects of gaseous and solid constituents of air pollution on endothelial function
Published in European heart journal (07-10-2018)“…Abstract Ambient air pollution is a leading cause of non-communicable disease globally. The largest proportion of deaths and morbidity due to air pollution is…”
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Organic Nitrate Therapy, Nitrate Tolerance, and Nitrate-Induced Endothelial Dysfunction: Emphasis on Redox Biology and Oxidative Stress
Published in Antioxidants & redox signaling (10-10-2015)“…Organic nitrates, such as nitroglycerin (GTN), isosorbide-5-mononitrate and isosorbide dinitrate, and pentaerithrityl tetranitrate (PETN), when given acutely,…”
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4
Endothelial nitric oxide synthase in vascular disease : From marvel to menace
Published in Circulation (New York, N.Y.) (04-04-2006)“…Nitric oxide (NO*) is an important protective molecule in the vasculature, and endothelial NO* synthase (eNOS) is responsible for most of the vascular NO*…”
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Regional and global contributions of air pollution to risk of death from COVID-19
Published in Cardiovascular research (01-12-2020)“…Abstract Aims The risk of mortality from the coronavirus disease that emerged in 2019 (COVID-19) is increased by comorbidity from cardiovascular and pulmonary…”
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Ambient Air Pollution Increases the Risk of Cerebrovascular and Neuropsychiatric Disorders through Induction of Inflammation and Oxidative Stress
Published in International journal of molecular sciences (17-06-2020)“…Exposure to ambient air pollution is a well-established determinant of health and disease. The Lancet Commission on pollution and health concludes that air…”
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Cardiovascular disease burden from ambient air pollution in Europe reassessed using novel hazard ratio functions
Published in European heart journal (21-05-2019)“…Abstract Aims Ambient air pollution is a major health risk, leading to respiratory and cardiovascular mortality. A recent Global Exposure Mortality Model,…”
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eNOS uncoupling in cardiovascular diseases--the role of oxidative stress and inflammation
Published in Current pharmaceutical design (01-01-2014)“…Many cardiovascular diseases and drug-induced complications are associated with - or even based on - an imbalance between the formation of reactive oxygen and…”
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Personal-Level Protective Actions Against Particulate Matter Air Pollution Exposure: A Scientific Statement From the American Heart Association
Published in Circulation (New York, N.Y.) (08-12-2020)“…Since the publication of the last American Heart Association scientific statement on air pollution and cardiovascular disease in 2010, unequivocal evidence of…”
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10
Vascular Inflammation and Oxidative Stress: Major Triggers for Cardiovascular Disease
Published in Oxidative medicine and cellular longevity (01-01-2019)“…Cardiovascular disease is a leading cause of death and reduced quality of life, proven by the latest data of the Global Burden of Disease Study, and is only…”
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Air pollution, the underestimated cardiovascular risk factor
Published in European heart journal (21-02-2020)Get full text
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Redox regulation of cardiovascular inflammation – Immunomodulatory function of mitochondrial and Nox-derived reactive oxygen and nitrogen species
Published in Free radical biology & medicine (01-08-2017)“…Oxidative stress is a major hallmark of cardiovascular diseases although a causal link was so far not proven by large clinical trials. However, there is a…”
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13
Loneliness in the general population: prevalence, determinants and relations to mental health
Published in BMC psychiatry (20-03-2017)“…While loneliness has been regarded as a risk to mental and physical health, there is a lack of current community data covering a broad age range. This study…”
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Environmental risk factors and cardiovascular diseases: a comprehensive expert review
Published in Cardiovascular research (10-11-2022)“…Non-communicable diseases (NCDs) are fatal for more than 38 million people each year and are thus the main contributors to the global burden of disease…”
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Explaining the Phenomenon of Nitrate Tolerance
Published in Circulation research (30-09-2005)“…During the last century, nitroglycerin has been the most commonly used antiischemic and antianginal agent. Unfortunately, after continuous application, its…”
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Trends in thrombolytic treatment and outcomes of acute pulmonary embolism in Germany
Published in European heart journal (21-01-2020)“…Abstract Aims Pulmonary embolism (PE) is the third most common cardiovascular cause of death; systemic thrombolysis is potentially lifesaving treatment in…”
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17
Environmental stressors and cardio-metabolic disease: part II-mechanistic insights
Published in European heart journal (21-02-2017)“…Environmental factors can act as facilitators of chronic non-communicable diseases. Ambient noise and air pollution collectively outrank all other…”
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18
Heightened amygdalar activity mediates the cardiometabolic effects of transportation noise stress
Published in Psychoneuroendocrinology (01-09-2021)“…Mechanistic mouse data revealed noise-induced neuroactivation, neuroinflammation and cerebral oxidative stress (reviewed in Munzel et al. (2020a, 2021)). This…”
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Global health burden of ambient PM2.5 and the contribution of anthropogenic black carbon and organic aerosols
Published in Environment international (15-01-2022)“…[Display omitted] Chronic exposure to fine particulate matter (PM2.5) poses a major global health risk, commonly assessed by assuming equivalent toxicity for…”
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Exploiting the Pleiotropic Antioxidant Effects of Established Drugs in Cardiovascular Disease
Published in International journal of molecular sciences (05-08-2015)“…Cardiovascular disease is a leading cause of death and reduced quality of life worldwide. Arterial vessels are a primary target for endothelial dysfunction and…”
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