Search Results - "Thomas, Jemima C"

Crystal Structures of Stapled and Hydrogen Bond Surrogate Peptides Targeting a Fully Buried Protein–Helix Interaction by Douse, Christopher H, Maas, Sabrina J, Thomas, Jemima C, Garnett, James A, Sun, Yunyun, Cota, Ernesto, Tate, Edward W

“…Constrained α-helical peptides are an exciting class of molecule designed to disrupt protein–protein interactions (PPIs) at a surface-exposed helix binding…”
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Multimeric Complexes among Ankyrin-Repeat and SOCS-box Protein 9 (ASB9), ElonginBC, and Cullin 5: Insights into the Structure and Assembly of ECS-type Cullin-RING E3 Ubiquitin Ligases by Thomas, Jemima C, Matak-Vinkovic, Dijana, Van Molle, Inge, Ciulli, Alessio

“…Proteins of the ankyrin-repeat and SOCS-box (ASB) family act as the substrate-recognition subunits of ECS-type (ElonginBC–Cullin–SOCS-box) Cullin RING E3…”
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Structural and functional characterisation of human RNA helicase DHX8 provides insights into the mechanism of RNA-stimulated ADP release by Felisberto-Rodrigues, Catarina, Thomas, Jemima C, McAndrew, Craig, Le Bihan, Yann-Vaï, Burke, Rosemary, Workman, Paul, van Montfort, Rob L M

“…DHX8 is a crucial DEAH-box RNA helicase involved in splicing and required for the release of mature mRNA from the spliceosome. Here, we report the biochemical…”
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Inhibition of Ral GTPases Using a Stapled Peptide Approach by Thomas, Jemima C., Cooper, Jonathan M., Clayton, Natasha S., Wang, Chensu, White, Michael A., Abell, Chris, Owen, Darerca, Mott, Helen R.

“…Aberrant Ras signaling drives numerous cancers, and drugs to inhibit this are urgently required. This compelling clinical need combined with recent innovations…”
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Regulation of the Plasmodium motor complex: phosphorylation of myosin A tail-interacting protein (MTIP) loosens its grip on MyoA by Douse, Christopher H, Green, Judith L, Salgado, Paula S, Simpson, Peter J, Thomas, Jemima C, Langsley, Gordon, Holder, Anthony A, Tate, Edward W, Cota, Ernesto

“…The interaction between the C-terminal tail of myosin A (MyoA) and its light chain, myosin A tail domain interacting protein (MTIP), is an essential feature of…”
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Interaction and dynamics of the Plasmodium falciparum MTIP-MyoA complex, a key component of the invasion motor in the malaria parasite by Thomas, Jemima C, Green, Judith L, Howson, Ronald I, Simpson, Peter, Moss, David K, Martin, Stephen R, Holder, Anthony A, Cota, Ernesto, Tate, Edward W

“…The myosin tail domain interacting protein-myosin A (MTIP-MyoA) protein complex is an essential element of the motor driving invasion of red blood cells by the…”
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Regulation of the Plasmodium Motor Complex by Douse, Christopher H., Green, Judith L., Salgado, Paula S., Simpson, Peter J., Thomas, Jemima C., Langsley, Gordon, Holder, Anthony A., Tate, Edward W., Cota, Ernesto

“…The interaction between the C-terminal tail of myosin A (MyoA) and its light chain, myosin A tail domain interacting protein (MTIP), is an essential feature of…”
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