Search Results - "Thomas, James D"

Relative apical sparing of longitudinal strain using two-dimensional speckle-tracking echocardiography is both sensitive and specific for the diagnosis of cardiac amyloidosis by Phelan, Dermot, Collier, Patrick, Thavendiranathan, Paaladinesh, Popović, Zoran B, Hanna, Mazen, Plana, Juan Carlos, Marwick, Thomas H, Thomas, James D

“…The diagnosis of cardiac amyloidosis (CA) is challenging owing to vague symptomatology and non-specific echocardiographic findings. To describe regional…”
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2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: Executive Summary by Nishimura, Rick A., MD, MACC, FAHA, Otto, Catherine M., MD, FACC, FAHA, Bonow, Robert O., MD, MACC, FAHA, Carabello, Blase A., MD, FACC, Erwin, John P., MD, FACC, FAHA, Guyton, Robert A., MD, FACC, O'Gara, Patrick T., MD, FACC, FAHA, Ruiz, Carlos E., MD, PhD, FACC, Skubas, Nikolaos J., MD, FASE, Sorajja, Paul, MD, FACC, FAHA, Sundt, Thoralf M., MD, Thomas, James D., MD, FASE, FACC, FAHA

“…ACC/AHA Task Force Members Jeffrey L. Anderson, MD, FACC, FAHA, Chair, Jonathan L. Halperin, MD, FACC, FAHA, Chair-Elect, Nancy M. Albert, PhD, CCNS, CCRN,…”
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Definitions for a Common Standard for 2D Speckle Tracking Echocardiography: Consensus Document of the EACVI/ASE/Industry Task Force to Standardize Deformation Imaging by Voigt, Jens-Uwe, Pedrizzetti, Gianni, Lysyansky, Peter, Marwick, Tom H, Houle, Hélène, Baumann, Rolf, Pedri, Stefano, Ito, Yasuhiro, Abe, Yasuhiko, Metz, Stephen, Song, Joo Hyun, Hamilton, Jamie, Sengupta, Partho P, Kolias, Theodore J, d'Hooge, Jan, Aurigemma, Gerard P, Thomas, James D, Badano, Luigi Paolo

“…Recognizing the critical need for standardization in strain imaging, in 2010, the European Association of Echocardiography (now the European Association of…”
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Elimination of Toxic Microsatellite Repeat Expansion RNA by RNA-Targeting Cas9 by Batra, Ranjan, Nelles, David A., Pirie, Elaine, Blue, Steven M., Marina, Ryan J., Wang, Harrison, Chaim, Isaac A., Thomas, James D., Zhang, Nigel, Nguyen, Vu, Aigner, Stefan, Markmiller, Sebastian, Xia, Guangbin, Corbett, Kevin D., Swanson, Maurice S., Yeo, Gene W.

“…Microsatellite repeat expansions in DNA produce pathogenic RNA species that cause dominantly inherited diseases such as myotonic dystrophy type 1 and 2…”
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2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease by Nishimura, Rick A., MD, MACC, FAHA, Otto, Catherine M., MD, FACC, FAHA, Bonow, Robert O., MD, MACC, FAHA, Carabello, Blase A., MD, FACC, Erwin, John P., MD, FACC, FAHA, Guyton, Robert A., MD, FACC, O’Gara, Patrick T., MD, FACC, FAHA, Ruiz, Carlos E., MD, PhD, FACC, Skubas, Nikolaos J., MD, FASE, Sorajja, Paul, MD, FACC, FAHA, Sundt, Thoralf M., MD, Thomas, James D., MD, FASE, FACC, FAHA

“…An organized and directed approach to a thorough review of evidence has resulted in the production of clinical practice guidelines that assist clinicians in…”
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Pharmacologic modulation of RNA splicing enhances anti-tumor immunity by Lu, Sydney X., De Neef, Emma, Thomas, James D., Sabio, Erich, Rousseau, Benoit, Gigoux, Mathieu, Knorr, David A., Greenbaum, Benjamin, Elhanati, Yuval, Hogg, Simon J., Chow, Andrew, Ghosh, Arnab, Xie, Abigail, Zamarin, Dmitriy, Cui, Daniel, Erickson, Caroline, Singer, Michael, Cho, Hana, Wang, Eric, Lu, Bin, Durham, Benjamin H., Shah, Harshal, Chowell, Diego, Gabel, Austin M., Shen, Yudao, Liu, Jing, Jin, Jian, Rhodes, Matthew C., Taylor, Richard E., Molina, Henrik, Wolchok, Jedd D., Merghoub, Taha, Diaz, Luis A., Abdel-Wahab, Omar, Bradley, Robert K.

“…Although mutations in DNA are the best-studied source of neoantigens that determine response to immune checkpoint blockade, alterations in RNA splicing within…”
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Repeated ethanol exposure and withdrawal alters angiotensin‐converting enzyme 2 expression in discrete brain regions: Implications for SARS‐CoV‐2 neuroinvasion by Balasubramanian, Nagalakshmi, James, Thomas D., Selvakumar, Govindhasamy Pushpavathi, Reinhardt, Jessica, Marcinkiewcz, Catherine A.

“…Background People with alcohol use disorder (AUD) may be at higher risk for COVID‐19. Angiotensin‐converting enzyme 2 (ACE2) and transmembrane serine protease…”
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Improvement in Strain Concordance between Two Major Vendors after the Strain Standardization Initiative by Yang, Hong, BMed, Marwick, Thomas H., MBBS, PhD, MPH, Fukuda, Nobuaki, MD, Oe, Hiroki, MD, PhD, Saito, Makoto, MD, PhD, Thomas, James D., MD, PhD, Negishi, Kazuaki, MD, PhD

“…Background Disagreement of strain measurements among different vendors has provided an obstacle to the clinical use of strain. A joint standardization task…”
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Arp2/3 and Mena/VASP Require Profilin 1 for Actin Network Assembly at the Leading Edge by Skruber, Kristen, Warp, Peyton V., Shklyarov, Rachael, Thomas, James D., Swanson, Maurice S., Henty-Ridilla, Jessica L., Read, Tracy-Ann, Vitriol, Eric A.

“…Cells have many types of actin structures, which must assemble from a common monomer pool. Yet, it remains poorly understood how monomers are distributed to…”
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Sulfoxaflor and the sulfoximine insecticides: Chemistry, mode of action and basis for efficacy on resistant insects by Sparks, Thomas C., Watson, Gerald B., Loso, Michael R., Geng, Chaoxian, Babcock, Jon M., Thomas, James D.

“…•Sulfoxaflor (SFX) is a sulfoximine insecticide with a distinct mode of action (MoA).•SFX is not a neonicotinoid – different chemistry and structure activity…”
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RNA isoform screens uncover the essentiality and tumor-suppressor activity of ultraconserved poison exons by Thomas, James D., Polaski, Jacob T., Feng, Qing, De Neef, Emma J., Hoppe, Emma R., McSharry, Maria V., Pangallo, Joseph, Gabel, Austin M., Belleville, Andrea E., Watson, Jacqueline, Nkinsi, Naomi T., Berger, Alice H., Bradley, Robert K.

“…While RNA-seq has enabled comprehensive quantification of alternative splicing, no correspondingly high-throughput assay exists for functionally interrogating…”
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High hospital research participation and improved colorectal cancer survival outcomes: a population-based study by Downing, Amy, Morris, Eva Ja, Corrigan, Neil, Sebag-Montefiore, David, Finan, Paul J, Thomas, James D, Chapman, Michael, Hamilton, Russell, Campbell, Helen, Cameron, David, Kaplan, Richard, Parmar, Mahesh, Stephens, Richard, Seymour, Matt, Gregory, Walter, Selby, Peter

“…In 2001, the National Institute for Health Research Cancer Research Network (NCRN) was established, leading to a rapid increase in clinical research activity…”
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Intron retention induced by microsatellite expansions as a disease biomarker by Sznajder, Łukasz J., Thomas, James D., Carrell, Ellie M., Reid, Tammy, McFarland, Karen N., Cleary, John D., Oliveira, Ruan, Nutter, Curtis A., Bhatt, Kirti, Sobczak, Krzysztof, Ashizawa, Tetsuo, Thornton, Charles A., Ranum, Laura P. W., Swanson, Maurice S.

“…Expansions of simple sequence repeats, or microsatellites, have been linked to ∼30 neurological–neuromuscular diseases. While these expansions occur in coding…”
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Left Atrial Strain Measured by Two-Dimensional Speckle Tracking Represents a New Tool to Evaluate Left Atrial Function by Saraiva, Roberto M., MD, PhD, Demirkol, Sayit, MD, Buakhamsri, Adisai, MD, Greenberg, Neil, PhD, Popović, Zoran B., MD, PhD, Thomas, James D., MD, Klein, Allan L., MD

“…Background Left atrial (LA) strain (ϵ) and ϵ rate (SR) analysis by two-dimensional speckle tracking can represent a new tool to evaluate LA function. To assess…”
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Usefulness of Plasma Galectin-3 Levels in Systolic Heart Failure to Predict Renal Insufficiency and Survival by Tang, W.H. Wilson, MD, Shrestha, Kevin, AB, Shao, Zhili, MD, PhD, Borowski, Allen G., RDCS, Troughton, Richard W., MBBS, Thomas, James D., MD, Klein, Allan L., MD

“…Galectin-3 plays an important role in fibroblast activation and fibrosis in animal models. Increased galectin-3 levels are associated with poor long-term…”
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Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy by Thomas, James D, Sznajder, Łukasz J, Bardhi, Olgert, Aslam, Faaiq N, Anastasiadis, Zacharias P, Scotti, Marina M, Nishino, Ichizo, Nakamori, Masayuki, Wang, Eric T, Swanson, Maurice S

“…Myotonic dystrophy type 1 (DM1) is a CTG microsatellite expansion (CTG ) disorder caused by expression of CUG RNAs. These mutant RNAs alter the activities of…”
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APC mutations dysregulate alternative polyadenylation in cancer by Gabel, Austin M, Belleville, Andrea E, Thomas, James D, Pineda, Jose Mario Bello, Bradley, Robert K

“…Alternative polyadenylation (APA) affects most human genes and is recurrently dysregulated in all studied cancers. However, the mechanistic origins of this…”
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Multiplexed screening reveals how cancer-specific alternative polyadenylation shapes tumor growth in vivo by Gabel, Austin M., Belleville, Andrea E., Thomas, James D., McKellar, Siegen A., Nicholas, Taylor R., Banjo, Toshihiro, Crosse, Edie I., Bradley, Robert K.

“…Alternative polyadenylation (APA) is strikingly dysregulated in many cancers. Although global APA dysregulation is frequently associated with poor prognosis,…”
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An autoregulatory poison exon in Smndc1 is conserved across kingdoms and influences organism growth by Belleville, Andrea E, Thomas, James D, Tonnies, Jackson, Gabel, Austin M, Borrero Rossi, Andrea, Singh, Priti, Queitsch, Christine, Bradley, Robert K

“…Many of the most highly conserved elements in the human genome are "poison exons," alternatively spliced exons that contain premature termination codons and…”
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Need for a Global Definition of Normative Echo Values—Rationale and Design of the World Alliance of Societies of Echocardiography Normal Values Study (WASE) by Asch, Federico M., Banchs, Jose, Price, Rhonda, Rigolin, Vera, Thomas, James D., Weissman, Neil J., Lang, Roberto M.

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