Search Results - "Thomas, Giju"

Initial clinical experiences using the intraoperative probe‐based parathyroid autofluorescence identification system—PTeye™ during thyroid and parathyroid procedures by Kiernan, Colleen M., Thomas, Giju, Baregamian, Naira, Solόrzano, Carmen C.

“…Background and Objective The Food and Drug Administration has cleared a probe‐based near‐infrared autofluorescence (NIRAF) detection system called PTeye™ as an…”
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Clinical translational application of Raman spectroscopy to advance Benchside biochemical characterization to bedside diagnosis of esophageal diseases by Hiremath, Girish, Locke, Andrea, Sivakumar, Adithya, Thomas, Giju, Mahadevan‐Jansen, Anita

“…Esophageal diseases result in significant mortality, morbidity, and health care costs worldwide. Current approaches to detect and monitor esophageal diseases…”
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Comparing laser speckle contrast imaging and indocyanine green angiography for assessment of parathyroid perfusion by Mannoh, Emmanuel A., Baregamian, Naira, Thomas, Giju, Solόrzano, Carmen C., Mahadevan-Jansen, Anita

“…Accurate intraoperative assessment of parathyroid blood flow is crucial to preserve function postoperatively. Indocyanine green (ICG) angiography has been…”
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Probing metabolic alterations in breast cancer in response to molecular inhibitors with Raman spectroscopy and validated with mass spectrometry by Wen, Xiaona, Ou, Yu-Chuan, Bogatcheva, Galina, Thomas, Giju, Mahadevan-Jansen, Anita, Singh, Bhuminder, Lin, Eugene C, Bardhan, Rizia

“…Rapid and accurate response to targeted therapies is critical to differentiate tumors that are resistant to treatment early in the regimen. In this work, we…”
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Identifying Parathyroids in Pediatric Thyroid/Parathyroid Surgery by Near Infrared Autofluorescence by Belcher, Ryan H., Thomas, Giju, Willmon, Parker A., Gallant, Jean‐Nicolas, Baregamian, Naira, Lopez, Monica E., Solόrzano, Carmen C., Mahadevan‐Jansen, Anita

“…Objectives Compared to adult patients undergoing thyroid surgery, pediatric patients have higher rates of hypoparathyroidism often related to parathyroid gland…”
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Comparing intraoperative parathyroid identification based on surgeon experience versus near infrared autofluorescence detection – A surgeon-blinded multi-centric study by Thomas, Giju, Solórzano, Carmen C., Baregamian, Naira, Mannoh, Emmanuel A., Gautam, Rekha, Irlmeier, Rebecca T., Ye, Fei, Nelson, Jon A., Long, Samuel E., Gauger, Paul G., Magner, Alexa, Metcalf, Tyler, Shirley, Lawrence A., Phay, John E., Mahadevan-Jansen, Anita

“…Near infrared autofluorescence (NIRAF) detection has previously demonstrated significant potential for real-time parathyroid gland identification. However, the…”
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Label-free intraoperative nerve detection and visualization using ratiometric diffuse reflectance spectroscopy by Throckmorton, Graham A., Haugen, Ezekiel, Thomas, Giju, Willmon, Parker, Baba, Justin S., Solórzano, Carmen C., Mahadevan-Jansen, Anita

“…Iatrogenic nerve injuries contribute significantly to postoperative morbidity across various surgical disciplines and occur in approximately 500,000 cases…”
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Engineering functional 3-dimensional patient-derived endocrine organoids for broad multiplatform applications by Baregamian, Naira, Sekhar, Konjeti R., Krystofiak, Evan S., Vinogradova, Maria, Thomas, Giju, Mannoh, Emmanuel, Solórzano, Carmen C., Kiernan, Colleen M., Mahadevan-Jansen, Anita, Abumrad, Naji, Freeman, Michael L., Weiss, Vivian L., Rathmell, Jeffrey C., Rathmell, W. Kimryn

“…Recent advancements in 3-dimensional patient-derived organoid models have revolutionized the field of cancer biology. There is an urgent need for development…”
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Development of an imaging device for label‐free parathyroid gland identification and vascularity assessment by Mannoh, Emmanuel A., Parker, Logan B., Thomas, Giju, Solórzano, Carmen C., Mahadevan‐Jansen, Anita

“…During thyroid surgeries, it is important for surgeons to accurately identify healthy parathyroid glands and assess their vascularity to preserve their…”
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Enhanced characterization of breast cancer phenotypes using Raman micro-spectroscopy on stainless steel substrate by Thomas, Giju, Fitzgerald, Sean T, Gautam, Rekha, Chen, Fuyao, Haugen, Ezekiel, Rasiah, Pratheepa Kumari, Adams, Wilson R, Mahadevan-Jansen, Anita

“…Biochemical insights into varying breast cancer (BC) phenotypes can provide a fundamental understanding of BC pathogenesis, while identifying novel therapeutic…”
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Advances and challenges in label-free nonlinear optical imaging using two-photon excitation fluorescence and second harmonic generation for cancer research by Thomas, Giju, van Voskuilen, Johan, Gerritsen, Hans C., Sterenborg, H.J.C.M.

“…•Label-free nonlinear optical imaging (NLOI) is a promising tool for cancer diagnosis.•Label-free NLOI can detect microscopic changes in cancerous tissues…”
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Novel Insights Into Tissue-Specific Biochemical Alterations in Pediatric Eosinophilic Esophagitis Using Raman Spectroscopy by Hiremath, Girish, Locke, Andrea, Thomas, Giju, Gautam, Rekha, Acra, Sari, Correa, Hernan, Dellon, Evan S., Mahadevan-Jansen, Anita

“…Elucidating esophageal biochemical composition in eosinophilic esophagitis (EoE) can offer novel insights into its pathogenesis, which remains unclear. Using…”
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Studying skin tumourigenesis and progression in immunocompetent hairless SKH1-hr mice using chronic 7,12-dimethylbenz(a)anthracene topical applications to develop a useful experimental skin cancer model by Thomas, Giju, Tuk, Bastiaan, Song, Ji-Ying, Truong, Hoa, Gerritsen, Hans C, de Gruijl, Frank R, Sterenborg, Henricus J C M

“…Previous studies have established that 7,12-dimethylbenz(a)anthracene (DMBA) can initiate skin tumourigenesis in conventional furred mouse models by acting on…”
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Detecting the Near Infrared Autofluorescence of the Human Parathyroid: Hype or Opportunity? by Solórzano, Carmen C., Thomas, Giju, Baregamian, Naira, Mahadevan-Jansen, Anita

“…OBJECTIVE:With the recent approval of 2 NIRAF-based devices for label-free identification of PG by the Food and Drug Administration, it becomes crucial to…”
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Current state of intraoperative use of near infrared fluorescence for parathyroid identification and preservation by Solórzano, Carmen C., Thomas, Giju, Berber, Eren, Wang, Tracy S., Randolph, Gregory W., Duh, Quan-Yang, Triponez, Frédéric

“…Finding and preserving normal parathyroid glands or localizing and removing diseased parathyroid glands are crucial steps to successful thyroid and parathyroid…”
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Imaging or Fiber Probe-Based Approach? Assessing Different Methods to Detect Near Infrared Autofluorescence for Intraoperative Parathyroid Identification by Thomas, Giju, Squires, Malcolm H., Metcalf, Tyler, Mahadevan-Jansen, Anita, Phay, John E.

“…Near infrared autofluorescence (NIRAF) can guide intraoperative parathyroid gland (PG) identification. NIRAF detection devices typically rely on imaging and…”
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Does the use of Probe-based Near Infrared Autofluorescence Parathyroid Detection Benefit Parathyroidectomy? A Randomized Single-center Clinical Trial by Kiernan, Colleen M., Thomas, Giju, Patel, Anuradha, Fan, Run, Ye, Fei, Willmon, Parker A., Solórzano, Carmen C.

“…To evaluate the benefits of probe-based near-infrared autofluorescence (NIRAF) parathyroid identification during parathyroidectomy. Intraoperative parathyroid…”
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Assessing Intraoperative Laser Speckle Contrast Imaging of Parathyroid Glands in Relation to Total Thyroidectomy Patient Outcomes by Mannoh, Emmanuel A, Thomas, Giju, Baregamian, Naira, Rohde, Sarah L, Solórzano, Carmen C, Mahadevan-Jansen, Anita

“…Accurate assessment of parathyroid gland vascularity is important during thyroidectomy to preserve the function of parathyroid glands and to prevent…”
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Innovative surgical guidance for label-free real-time parathyroid identification by Thomas, Giju, McWade, Melanie A., Nguyen, John Q., Sanders, Melinda E., Broome, James T., Baregamian, Naira, Solórzano, Carmen C., Mahadevan-Jansen, Anita

“…Difficulty in identifying the parathyroid gland during neck operations can lead to accidental parathyroid gland excisions and postsurgical hypocalcemia. A…”
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Feature Selection and Rapid Characterization of Bloodstains on Different Substrates by Gautam, Rekha, Peoples, Deandra, Jansen, Kiana, O’Connor, Maggie, Thomas, Giju, Vanga, Sandeep, Pence, Isaac J., Mahadevan-Jansen, Anita

“…Establishing the precise timeline of a crime can be challenging as current analytical techniques used suffer from many limitations and are destructive to the…”
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