Search Results - "Thomas, Emily E"
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The Rheology and Printability of Cartilage Matrix-Only Biomaterials
Published in Biomolecules (Basel, Switzerland) (17-06-2022)“…The potential chondroinductivity from cartilage matrix makes it promising for cartilage repair; however, cartilage matrix-based hydrogels developed thus far…”
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Extracellular matrix-templating fibrous hydrogels promote ovarian tissue remodeling and oocyte growth
Published in Bioactive materials (01-02-2024)“…Synthetic matrices which mimic the extracellular composition of native tissue create a comprehensive model for studying development and disease. Here, we have…”
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Exploring Maleimide-Based Nanoparticle Surface Engineering to Control Cellular Interactions
Published in ACS applied nano materials (27-03-2020)“…Nanoparticle cellular interactions are governed by nanoparticle surface chemistry and the surface display of functional (bio)molecules. To conjugate and…”
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Development and quantitative characterization of the precursor rheology of hyaluronic acid hydrogels for bioprinting
Published in Acta biomaterialia (01-09-2019)“…[Display omitted] Bioprinting technologies have tremendous potential for advancing regenerative medicine due to the precise spatial control over depositing a…”
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High-stiffness, fast-crosslinking, cartilage matrix bioinks
Published in Journal of biomechanics (01-02-2023)“…Scaffolds derived from cartilage extracellular matrix may contain intrinsic chondroinductivity and have promise for cartilage regeneration. Cartilage is…”
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Assessing nanoparticle colloidal stability with single-particle inductively coupled plasma mass spectrometry (SP-ICP-MS)
Published in Analytical and bioanalytical chemistry (01-09-2020)“…Biological interactions, toxicity, and environmental fate of engineered nanoparticles are affected by colloidal stability and aggregation. To assess…”
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Conductive and injectable hyaluronic acid/gelatin/gold nanorod hydrogels for enhanced surgical translation and bioprinting
Published in Journal of biomedical materials research. Part A (01-02-2022)“…There is growing evidence indicating the need to combine the rehabilitation and regenerative medicine fields to maximize functional recovery after spinal cord…”
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Metalloprotein switches that display chemical-dependent electron transfer in cells
Published in Nature chemical biology (01-02-2019)“…Biological electron transfer is challenging to directly regulate using environmental conditions. To enable dynamic, protein-level control over energy flow in…”
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A Split Transcriptional Repressor That Links Protein Solubility to an Orthogonal Genetic Circuit
Published in ACS synthetic biology (21-09-2018)“…Monitoring the aggregation of proteins within the cellular environment is key to investigating the molecular mechanisms underlying the formation of off-pathway…”
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10
Tolerance of a Knotted Near-Infrared Fluorescent Protein to Random Circular Permutation
Published in Biochemistry (Easton) (12-07-2016)“…Bacteriophytochrome photoreceptors (BphP) are knotted proteins that have been developed as near-infrared fluorescent protein (iRFP) reporters of gene…”
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Programming Post-Translational Control over the Metabolic Labeling of Cellular Proteins with a Noncanonical Amino Acid
Published in ACS synthetic biology (18-08-2017)“…Transcriptional control can be used to program cells to label proteins with noncanonical amino acids by regulating the expression of orthogonal aminoacyl tRNA…”
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12
The Structure of a Thermophilic Kinase Shapes Fitness upon Random Circular Permutation
Published in ACS synthetic biology (20-05-2016)“…Proteins can be engineered for synthetic biology through circular permutation, a sequence rearrangement in which native protein termini become linked and new…”
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13
Early myogenic responses to acute exercise before and after resistance training in young men
Published in Physiological reports (01-09-2015)“…To enable dynamic regulation of muscle mass and myofiber repair following injury, a satellite cell precursor population exists to supply additional nuclei…”
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Combining Fragmentation of an Amino Acyl tRNA Synthetase with Fusion to Interacting Proteins to Increase Control Over Protein Metabolic Labeling
Published in Biophysical journal (16-02-2016)Get full text
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15
Characterization of pentenoate-functionalized hyaluronic acid and pentenoate-functionalized gelatin hydrogels for printing and future surgical placement in regenerative medicine applications
Published in Materialia (01-12-2024)“…Injectable hydrogels with in situ crosslinking may be more suitable than pre-fabricated scaffolds for surgical delivery to clinical injuries. However, low…”
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16
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Published in Journal of biomedical materials research. Part A (01-02-2022)Get full text
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Programming post-translational control over the metabolic labeling of cellular proteins with a non-canonical amino acid
Published in ACS synthetic biology (17-05-2017)“…Transcriptional control can be used to program cells to label proteins with non-canonical amino acids by regulating the expression of orthogonal aminoacyl tRNA…”
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