Search Results - "Thomas, Cynthia B"

Nanocomposite scaffold for chondrocyte growth and cartilage tissue engineering: effects of carbon nanotube surface functionalization by Chahine, Nadeen O, Collette, Nicole M, Thomas, Cynthia B, Genetos, Damian C, Loots, Gabriela G

“…The goal of this study was to assess the long-term biocompatibility of single-wall carbon nanotubes (SWNTs) for tissue engineering of articular cartilage. We…”
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SOST Inhibits Prostate Cancer Invasion by Hudson, Bryan D, Hum, Nicholas R, Thomas, Cynthia B, Kohlgruber, Ayano, Sebastian, Aimy, Collette, Nicole M, Coleman, Matthew A, Christiansen, Blaine A, Loots, Gabriela G

“…Inhibitors of Wnt signaling have been shown to be involved in prostate cancer (PC) metastasis; however the role of Sclerostin (Sost) has not yet been explored…”
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Effect of age and cytoskeletal elements on the indentation-dependent mechanical properties of chondrocytes by Chahine, Nadeen O, Blanchette, Craig, Thomas, Cynthia B, Lu, Jeffrey, Haudenschild, Dominik, Loots, Gabriela G

“…Articular cartilage chondrocytes are responsible for the synthesis, maintenance, and turnover of the extracellular matrix, metabolic processes that contribute…”
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No Evidence for Differences in DNA Damage Assessed before and after a Cancer Diagnosis by Bhatti, Parveen, Sigurdson, Alice J, Thomas, Cynthia B, Iwan, Allison, Alexander, Bruce H, Kampa, Diane, Bowen, Laura, Doody, Michele Morin, Jones, Irene M

“…The overwhelming majority of studies that have found increased cancer risk associated with functional deficits in DNA repair used a case-control design, in…”
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Three Somatic Genetic Biomarkers and Covariates in Radiation-Exposed Russian Cleanup Workers of the Chernobyl Nuclear Reactor 6–13 Years after Exposure by Jones, Irene M., Galick, Heather, Kato, Paula, Langlois, Richard G., Mendelsohn, Mortimer L., Murphy, Gloria A., Pleshanov, Pavel, Ramsey, Marilyn J., Thomas, Cynthia B., Tucker, James D., Tureva, Ludmila, Vorobtsova, Irina, Nelson, David O.

“…Jones, I. M., Galick, H., Kato, P., Langlois, R. G., Mendelsohn, M. L., Murphy, G. A., Pleshanov, P., Ramsey, M. J., Thomas, C. B., Tucker, J. D., Tureva, L.,…”
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Unique DNA-barcoded aerosol test particles for studying aerosol transport by Harding, Ruth N., Hara, Christine A., Hall, Sara B., Vitalis, Elizabeth A., Thomas, Cynthia B., Jones, A. Daniel, Day, James A., Tur-Rojas, Vicente R., Jorgensen, Trond, Herchert, Edwin, Yoder, Richard, Wheeler, Elizabeth K., Farquar, George R.

“…Data are presented for the first use of novel DNA-barcoded aerosol test particles that have been developed to track the fate of airborne contaminants in…”
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Prospective analysis of DNA damage and repair markers of lung cancer risk from the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial by SIGURDSON, Alice J, JONES, Irene M, THOMAS, Cynthia B, REDING, Douglas J, HAYES, Richard B, CAPORASO, Neil E, QINGYI WEI, XIFENG WU, SPITZ, Margaret R, STRAM, Douglas A, GROSS, Myron D, HUANG, Wen-Yi, WANG, Li-E, JIAN GU

“…Mutagen challenge and DNA repair assays have been used in case-control studies for nearly three decades to assess human cancer risk. The findings still…”
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New insights into the Fanconi anemia pathway from an isogenic FancG hamster CHO mutant by Tebbs, Robert S., Hinz, John M., Yamada, N. Alice, Wilson, James B., Salazar, Edmund P., Thomas, Cynthia B., Jones, Irene M., Jones, Nigel J., Thompson, Larry H.

“…The Fanconi anemia (FA) proteins overlap with those of homologous recombination through FANCD1/BRCA2, but the biochemical functions of other FA proteins are…”
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Exploration of methods to identify polymorphisms associated with variation in DNA repair capacity phenotypes by Jones, Irene M, Thomas, Cynthia B, Xi, Tina, Mohrenweiser, Harvey W, Nelson, David O

“…Elucidating the relationship between polymorphic sequences and risk of common disease is a challenge. For example, although it is clear that variation in DNA…”
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DNA damage among thyroid cancer and multiple cancer cases, controls, and long-lived individuals by Sigurdson, Alice J., Hauptmann, Michael, Alexander, Bruce H., Doody, Michele Morin, Thomas, Cynthia B., Struewing, Jeffery P., Jones, Irene M.

“…Variation in the detection, signaling, and repair of DNA damage contributes to human cancer risk. To assess capacity to modulate endogenous DNA damage among…”
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A comparison of somatic mutational spectra in healthy study populations from Russia, Sweden and USA by Noori, Peri, Hou, Saimei, Jones, Irene M., Thomas, Cynthia B., Lambert, Bo

“…A comparison of mutation spectra at the hypoxanthine–guanine phosphoribosyl transferase (HPRT) gene of peripheral blood T-lymphocytes may provide an insight…”
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Induction and decline of HPRT mutants and deletions following a low dose radiation exposure at Chernobyl by Thomas, Cynthia B, Nelson, David O, Pleshanov, Pavel, Jones, Irene M

“…This study was conducted to evaluate the ability of mutation in the hypoxanthine-phosphoribosyltransferase gene (HPRT) to detect radiation-induced mutation in…”
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Elevated frequencies of hypoxanthine phosphoribosyltransferase lymphocyte mutants are detected in Russian liquidators 6 to 10 years after exposure to radiation from the Chernobyl nuclear power plant accident by Thomas, Cynthia B, Nelson, David O, Pleshanov, Pavel, Vorobstova, Irina, Tureva, Ludmila, Jensen, Ronald, Jones, Irene M

“…This study was conducted to determine whether the frequency of hypoxanthine phosphoribosyltransferase ( HPRT) deficient lymphocyte mutants would detect an…”
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Specific Interventions at a Proprietary Postsecondary Institution as It Relates to the Individual with Learning Disabilities: A Case Study Analysis of a Student Services Office by Thomas, Cynthia B

“…Purpose and Method of Study The purpose of this single case study was to identify and describe specific accommodations and modifications used by a four-year…”
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Characterization of in vivo Somatic Mutations at the Hypoxanthine Phosphoribosyltransferase Gene of a Human Control Population by Burkhart-Schultz, Karolyn, Thomas, Cynthia B., Thompson, Claudia L., Strout, Cheryl L., Brinson, Eleanor, Jones, Irene M.

“…The ability to recognize a change in mutation spectrum after an exposure to a toxic substance and then relate that exposure to health risk depends on the…”
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Total gene deletions and mutant frequency of the HPRT gene as indicators of radiation exposure in Chernobyl liquidators by Jones, I M, Thomas, C B, Haag, K, Pleshanov, P, Vorobstova, I, Tureva, L, Nelson, D O

“…This study was conducted to determine the utility of deletion spectrum and mutant frequency (MF) of the hypoxanthine phosphoribosyl transferase gene (HPRT) as…”
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Human in vivo somatic mutation measured at two loci: individuals with stably elevated background erythrocyte glycophorin A (gpa) variant frequencies exhibit normal T-lymphocyte hprt mutant frequencies by Bigbee, W L, Fuscoe, J C, Grant, S G, Jones, I M, Gorvad, A E, Harrington-Brock, K, Strout, C L, Thomas, C B, Moore, M M

“…A survey of glycophorin A (gpa) in vivo somatic cell mutation in a population of 394 healthy people from 8 to 77 years of age (mean age +/- SD 41 +/- 15 years)…”
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Endogenous DNA damage and testicular germ cell tumors by Cook, M.B, Sigurdson, A.J, Jones, I.M, Thomas, C.B, Graubard, B.I, Korde, L, Greene, M.H, McGlynn, K.A

“…Testicular germ cell tumors are comprised of two histologic groups, seminomas and non-seminomas. We postulated that the possible divergent pathogeneses of…”
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Induction and decline of HPRT mutants and deletions following a low dose radiation exposure at Chernobyl by THOMAS, Cynthia B, NELSON, David O, PLESHANOV, Pavel, JONES, Irene M

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Impact of age and environment on somatic mutation at the hprt gene of T lymphocytes in humans by Jones, Irene M., Thomas, Cynthia B., Tucker, Bethany, Thompson, Claudia L., Pleshanov, Pavel, Vorobtsova, Irena, Moore, Dan H.

“…Analysis of two human populations for dependence of somatic mutation on age has revealed both similarities and differences. The studies performed employed…”
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