Search Results - "Thomas, Cody T"
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Splice-Junction-Based Mapping of Alternative Isoforms in the Human Proteome
Published in Cell reports (Cambridge) (10-12-2019)“…The protein-level translational status and function of many alternative splicing events remain poorly understood. We use an RNA sequencing (RNA-seq)-guided…”
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Proteomic signatures of acute oxidative stress response to paraquat in the mouse heart
Published in Scientific reports (28-10-2020)“…The heart is sensitive to oxidative damage but a global view on how the cardiac proteome responds to oxidative stressors has yet to fully emerge. Using…”
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Identifying High-Priority Proteins Across the Human Diseasome Using Semantic Similarity
Published in Journal of proteome research (07-12-2018)“…Identifying the genes and proteins associated with a biological process or disease is a central goal of the biomedical research enterprise. However, relatively…”
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Shotgun Proteomics Sample Processing Automated by an Open-Source Lab Robot
Published in Journal of visualized experiments (28-10-2021)“…Mass spectrometry-based shotgun proteomics experiments require multiple sample preparation steps, including enzymatic protein digestion and clean-up, which can…”
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Transcriptome features of striated muscle aging and predictability of protein level changes
Published in Molecular omics (11-10-2021)“…We performed total RNA sequencing and multi-omics analysis comparing skeletal muscle and cardiac muscle in young adult (4 months) early aging (20 months) mice…”
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Abstract 279: Effects of Acute Oxidative Stress on Cardiac Proteome Dynamics
Published in Circulation research (03-08-2018)“…Abstract only Introduction: Acute reactive oxygen species exposure is thought to trigger endoplasmic reticulum (ER) stress and unfolded protein response (UPR)…”
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Abstract 315: Time-resolved Expression of Membrane-targeted Proteins During Ipsc-cardiomyocyte Differentiation
Published in Circulation research (03-08-2018)“…Abstract only Background: The ability to create human cardiomyocytes from induced pluripotent stem cells (iPSCs) has spurred advances in disease modeling and…”
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