Search Results - "Thomas, Anitha"
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Manufacturing Considerations for the Development of Lipid Nanoparticles Using Microfluidics
Published in Pharmaceutics (15-11-2020)“…In the recent of years, the use of lipid nanoparticles (LNPs) for RNA delivery has gained considerable attention, with a large number in the clinical pipeline…”
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Polymeric and lipid nanoparticles for delivery of self-amplifying RNA vaccines
Published in Journal of controlled release (10-10-2021)“…Self-amplifying RNA (saRNA) is a next-generation vaccine platform, but like all nucleic acids, requires a delivery vehicle to promote cellular uptake and…”
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Strategies for primary HPV test-based cervical cancer screening programme in resource-limited settings in India: Results from a quasi-experimental pragmatic implementation trial
Published in PloS one (05-04-2024)“…In order for low and middle income countries (LMIC) to transition to Human Papilloma Virus (HPV) test based cervical cancer screening, a greater understanding…”
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Development of a liposomal nanoparticle formulation of 5-Fluorouracil for parenteral administration: Formulation design, pharmacokinetics and efficacy
Published in Journal of controlled release (10-03-2011)“…5-Fluorouracil (5-FU) is a small, very membrane permeable drug that is poorly retained within the aqueous compartment of liposomal nanoparticles (LNP). To…”
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Malignant metastatic steroid cell tumor NOS: A rare presentation of a subtype of sex cord stromal tumor
Published in Gynecologic oncology reports (01-04-2023)“…•Steroid cell tumor NOS are extremely rare and often benign.•Malignant metastatic steroid cell tumor NOS are very difficult to manage.•Combination of surgery,…”
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ESGO Quality Indicators for Surgical Management of Cervical Cancer: An Audit of Compliance of a Tertiary Care Center
Published in South Asian journal of cancer (22-07-2024)“…Objective This article assesses the compliance of surgical management of carcinoma cervix, to the quality indicators for treatment put forth by the European…”
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OX40 agonist stimulation increases and sustains humoral and cell-mediated responses to SARS-CoV-2 protein and saRNA vaccines
Published in Frontiers in immunology (27-09-2022)“…To prevent SARS-CoV-2 infections and generate long-lasting immunity, vaccines need to generate strong viral-specific B and T cell responses. Previous results…”
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Innate defense regulator peptide 1018 protects against perinatal brain injury
Published in Annals of neurology (01-03-2014)“…Objective There is currently no pharmacological treatment that provides protection against brain injury in neonates. It is known that activation of an innate…”
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The clinico pathological features and survival in serous endometrial cancers
Published in Gynecologic oncology reports (01-06-2023)“…•Serous endometrial cancers are uncommon among the endometrial cancers.•Patients diagnosed with these tumours have poor prognosis if not treated early and…”
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Secondary cytoreduction in recurrent ovarian cancer- experience from a tertiary care centre in India
Published in Gynecologic oncology reports (01-08-2024)“…•Recurrent ovarian cancer is a challenging disease with various therapeutic entities. Optimal cytoreduction is the key determinant of survival outcomes. This…”
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The autophagy inhibitor verteporfin moderately enhances the antitumor activity of gemcitabine in a pancreatic ductal adenocarcinoma model
Published in Journal of Cancer (01-01-2013)“…Pancreatic ductal adenocarcinoma (PDAC) is highly resistant to chemotherapy. It has been described as requiring elevated autophagy for growth and inhibiting…”
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Efficient removal of fluoride on aluminum modified activated carbon: an adsorption behavioral study and application to remediation of ground water
Published in Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering (2023)“…In recent times, ground water contamination by toxic elements is of great concern and it is to be addressed for consumption of human, animal, and plant growth…”
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13
On a Fractional Master Equation
Published in International Journal of Differential Equations (01-01-2011)“…A fractional order time-independent form of the wave equation or diffusion equation in two dimensions is obtained from the standard time-independent form of…”
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Different modes of DNA cleavage activity of dihydroxo-bridged dicopper(II) complexes having phenanthroline bases
Published in Journal of inorganic biochemistry (01-06-2004)“…Dihydroxo-bridged dicopper(II) complexes [{Cu(phen)} 2(μ-OH) 2](ClO 4) 2 ( 1), [{Cu(dpq)} 2(μ-OH) 2](ClO 4) 2 ( 2) and [{Cu(dppz)(DMF)} 2(μ-OH) 2](PF 6) 2 (…”
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Metastatic Tumors to the Ovary—a Surgeon’s Dilemma
Published in Indian journal of surgical oncology (01-03-2021)“…The ovary is a common site of metastasis. Differential diagnosis of ovarian carcinomas, including secondary tumors, remains a challenging task. Clinical…”
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Management Driven Structured Reporting in Ovarian Cancer
Published in Journal of Gastrointestinal and Abdominal Radiology (01-07-2020)“…Abstract Since majority (80%) of ovarian cancer patients present at an advanced stage, imaging performed on these patients have numerous findings. The…”
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Synthesis, crystal structure, and nuclease activity of planar mono-heterocyclic base copper(II) complexes
Published in Journal of inorganic biochemistry (01-02-2003)“…A series of mononuclear copper(II) complexes having a 1:1 molar ratio of copper and the planar heterocyclic base like 1,10-phenanthroline (phen),…”
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Outcomes of carcinosarcoma in a tertiary care institution in India
Published in South Asian Journal of Cancer (01-01-2018)“…Abstract Background: Carcinosarcoma is a rare malignancy, and reports are often mixed along with other sarcomas. The literature on uterine carcinosarcoma per…”
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Human papillomavirus and gene mutations in head and neck squamous carcinomas
Published in ANZ journal of surgery (01-05-2012)“…Background: Human papillomavirus (HPV) infection is implicated as an aetiological factor in head and neck squamous carcinomas (HNSCC), especially in the…”
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Transition metal-mediated liposomal encapsulation of irinotecan (CPT-11) stabilizes the drug in the therapeutically active lactone conformation
Published in Pharmaceutical research (01-12-2006)“…To determine whether entrapped transition metals could mediate the active encapsulation of the anticancer drug irinotecan into preformed liposomes. Further, to…”
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