Search Results - "Thoma, B."

Comparison of Pneumococcal Conjugate Polysaccharide and Free Polysaccharide Vaccines in Elderly Adults: Conjugate Vaccine Elicits Improved Antibacterial Immune Responses and Immunological Memory by de Roux, Andrés, Schmöele-Thoma, B., Siber, G. R., Hackell, J. G., Kuhnke, A., Ahlers, N., Baker, S. A., Razmpour, A., Emini, E. A., Fernsten, P. D., Gruber, W. C., Lockhart, S., Burkhardt, O., Welte, T., Lode, H. M.

“…Background. High functional antibody responses, establishment of immunologic memory, and unambiguous efficacy in infants suggest that an initial dose of…”
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A randomized, double-blind trial to evaluate immunogenicity and safety of 13-valent pneumococcal conjugate vaccine given concomitantly with trivalent influenza vaccine in adults aged ≥65 years by Schwarz, T.F, Flamaing, J, Rümke, H.C, Penzes, J, Juergens, C, Wenz, A, Jayawardene, D, Giardina, P, Emini, E.A, Gruber, W.C, Schmoele-Thoma, B

“…Abstract This randomized, double-blind study evaluated concomitant administration of 13-valent pneumococcal conjugate vaccine (PCV13) and trivalent inactivated…”
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A Population Pharmacokinetic Model for Vancomycin in Adult Patients Receiving Extracorporeal Membrane Oxygenation Therapy by Moore, JN, Healy, JR, Thoma, BN, Peahota, MM, Ahamadi, M, Schmidt, L, Cavarocchi, NC, Kraft, WK

“…The literature on the pharmacokinetics of vancomycin in patients undergoing extracorporeal membrane oxygenation (ECMO) therapy is sparse. A population…”
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Immunogenicity and safety of a 13-valent pneumococcal conjugate vaccine in adults 18–49 years of age, naive to 23-valent pneumococcal polysaccharide vaccine by Bryant, K.A, Frenck, R, Gurtman, A, Rubino, J, Treanor, J, Thompson, A, Jones, T.R, Sundaraiyer, V, Baxter, L.M, Gruber, W.C, Emini, E.A, Scott, D.A, Schmoele-Thoma, B

“…Highlights • PCV13 was immunogenic and well tolerated in adults of all ages. • Functional antibody titers were generally higher in adults 18–49 vs 60–64 years…”
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Rationale and design of CAPITA : a RCT of 13-valent conjugated pneumococcal vaccine efficacy among older adults by HAK, E, GROBBEE, D. E, PATTERSON, S, VAN ALPHEN, A. J, BONTEN, M. J. M, SANDERS, E. A. M, VERHEIJ, T. J. M, BOLKENBAAS, M, HUIJTS, S. M, GRUBER, W. C, TANSEY, S, MCDONOUGH, A, THOMA, B

“…The burden of community-acquired pneumonia (CAP) among the elderly is high and has increased over the last decades. Streptococcus pneumoniae is the most common…”
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Atypical Cowpox Virus Infection in a Series of Cats by Jungwirth, N., Puff, C., Köster, K., Mischke, R., Meyer, H., Stark, A., Thoma, B., Zöller, G., Seehusen, F., Hewicker-Trautwein, M., Beineke, A., Baumgärtner, W., Wohlsein, P.

“…Within 4 weeks, five cats with skin lesions affecting the hindlimbs and mainly consisting of oedema, hyperaemia and plaque-like alterations were presented to…”
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Dose-ranging study of a single injection of pneumococcal conjugate vaccine (1×, 2×, or 4×) in healthy subjects aged 70 years or older by Lode, H, Schmoele-Thoma, B, Gruber, W, Ahlers, N, Fernsten, P, Baker, S, Razmpour, A, Siber, G, Hackell, J, Lockhart, S, Burkhardt, O, Welte, T, de Roux, A

“…Abstract Healthy adults aged ≥70 years ( N = 443) with no history of pneumococcal vaccination received 7- or 9-valent pneumococcal conjugate vaccine (PCV7 or…”
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The safety, reactogenicity and immunogenicity of a 7-valent pneumococcal conjugate vaccine (7VPnC) concurrently administered with a combination DTaP-IPV-Hib vaccine by Schmitt, H.J, Faber, J, Lorenz, I, Schmöle-Thoma, B, Ahlers, N

“…To evaluate immune responses, safety and reactogenicity of the concomitant use of DTaP-IPV-Hib and the newly available 7-valent pneumococcal conjugate (7VPnC)…”
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Souvenir from South Africa by Antal, A. S., Flaig, M. J., Schneck, C., Thoma, B., Herzinger, T.

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Oncostatin M and leukemia inhibitory factor trigger overlapping and different signals through partially shared receptor complexes by Thoma, B, Bird, T A, Friend, D J, Gearing, D P, Dower, S K

“…Leukemia inhibitory factor (LIF) and oncostatin M (OSM) both bind to the same receptor with high affinity and thus mediate an overlapping spectrum of…”
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Prevalence of weight gain in patients with better renal transplant function by Thoma, B, Grover, V K, Shoker, A

“…This study investigates the association between renal function and change in weight after kidney transplantation. Retrospective analyses of 165 transplant…”
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Targeted disruption of the low-affinity leukemia inhibitory factor receptor gene causes placental, skeletal, neural and metabolic defects and results in perinatal death by Ware, C B, Horowitz, M C, Renshaw, B R, Hunt, J S, Liggitt, D, Koblar, S A, Gliniak, B C, McKenna, H J, Papayannopoulou, T, Thoma, B

“…The low-affinity receptor for leukemia inhibitory factor (LIFR) interacts with gp130 to induce an intracellular signal cascade. The LIFR-gp130 heterodimer is…”
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Immunoregulatory activity of recombinant human tumor necrosis factor (TNF)-alpha: induction of TNF receptors on human T cells and TNF-alpha- mediated enhancement of T cell responses by Scheurich, P, Thoma, B, Ucer, U, Pfizenmaier, K

“…The expression of specific tumor necrosis factor (TNF) membrane receptors and biological effects of recombinant TNF (rTNF)-alpha on normal human T lymphocytes…”
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Development of the cytodetachment technique to quantify mechanical adhesiveness of the single cell by Athanasiou, K.A, Thoma, B.S, Lanctot, D.R, Shin, D, Agrawal, C.M, LeBaron, R.G

“…Adhesion of cells to biomaterials or to components of the extracellular matrix is fundamental in many tissue engineering and biotechnological processes, as…”
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Human XPC-hHR23B interacts with XPA-RPA in the recognition of triplex-directed psoralen DNA interstrand crosslinks by Thoma, Brian S., Wakasugi, Mitsuo, Christensen, Jesper, Reddy, Madhava C., Vasquez, Karen M.

“…DNA interstrand crosslinks (ICLs) represent a severe form of damage that blocks DNA metabolic processes and can lead to cell death or carcinogenesis. The…”
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Critical DNA damage recognition functions of XPC-hHR23B and XPA-RPA in nucleotide excision repair by Thoma, Brian S., Vasquez, Karen M.

“…It has been reported that 80–90% of human cancers may result, in part, from DNA damage. Cell survival depends critically on the stability of our DNA and…”
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Change in Diuretic Dose After Initiation of a SGLT2 Inhibitor in Patients with Heart Failure with Reduced Ejection Fraction by Wildemann, R., Karalis, D.G., Mirachi, N., Thoma, B., D'Angelo, R.

“…This study was designed to evaluate the change in loop diuretic dose at three months post-initiation of a sodium-glucose cotransporter-2 inhibitor (SGLT2i) in…”
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Efficacy and Safety of a Bivalent RSV Prefusion F Vaccine in Older Adults by Walsh, Edward E., Pérez Marc, Gonzalo, Zareba, Agnieszka M., Falsey, Ann R., Jiang, Qin, Patton, Michael, Polack, Fernando P., Llapur, Conrado, Doreski, Pablo A., Ilangovan, Kumar, Rämet, Mika, Fukushima, Yasushi, Hussen, Nazreen, Bont, Louis J., Cardona, Jose, DeHaan, Elliot, Castillo Villa, Giselle, Ingilizova, Marinela, Eiras, Daniel, Mikati, Tarek, Shah, Rupal N., Schneider, Katherine, Cooper, David, Koury, Kenneth, Lino, Maria-Maddalena, Anderson, Annaliesa S., Jansen, Kathrin U., Swanson, Kena A., Gurtman, Alejandra, Gruber, William C., Schmoele-Thoma, Beate

“…In a phase 3 trial, adults (≥60 years of age) received one 120-μg dose of RSVpreF vaccine (17,215) or placebo (17,069). Vaccine efficacy against RSV-associated…”
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The clinical learning environment by Nordquist, Jonas, Hall, Jena, Caverzagie, Kelly, Snell, Linda, Chan, Ming-Ka, Thoma, Brent, Razack, Saleem, Philibert, Ingrid

“…Learning in a clinical context is foundational in the training of health professionals; there is simply no alternative. The subject of the clinical learning…”
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Polysaccharide Conjugate Vaccine against Pneumococcal Pneumonia in Adults by Bonten, Marc J.M, Huijts, Susanne M, Bolkenbaas, Marieke, Webber, Chris, Patterson, Scott, Gault, Samantha, van Werkhoven, Cornelis H, van Deursen, Anna M.M, Sanders, Elisabeth A.M, Verheij, Theo J.M, Patton, Michael, McDonough, Anne, Moradoghli-Haftvani, Anita, Smith, Helen, Mellelieu, Tracey, Pride, Michael W, Crowther, Graham, Schmoele-Thoma, Beate, Scott, Daniel A, Jansen, Kathrin U, Lobatto, Rita, Oosterman, Bas, Visser, Nils, Caspers, Esther, Smorenburg, Andre, Emini, Emilio A, Gruber, William C, Grobbee, Diederick E

“…In this double-blind, placebo-controlled trial involving more than 84,000 Dutch adults, the 13-valent pneumococcal conjugate vaccine was found to prevent…”
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