Search Results - "Thom, Cristian"

Structural basis for the activation and ligand recognition of the human oxytocin receptor by Waltenspühl, Yann, Ehrenmann, Janosch, Vacca, Santiago, Thom, Cristian, Medalia, Ohad, Plückthun, Andreas

“…The small cyclic neuropeptide hormone oxytocin (OT) and its cognate receptor play a central role in the regulation of social behaviour and sexual reproduction…”
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Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control by Schmid, Markus, Ernst, Patrick, Honegger, Annemarie, Suomalainen, Maarit, Zimmermann, Martina, Braun, Lukas, Stauffer, Sarah, Thom, Cristian, Dreier, Birgit, Eibauer, Matthias, Kipar, Anja, Vogel, Viola, Greber, Urs F., Medalia, Ohad, Plückthun, Andreas

“…Most systemic viral gene therapies have been limited by sequestration and degradation of virions, innate and adaptive immunity, and silencing of therapeutic…”
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Structures of neurokinin 1 receptor in complex with Gq and Gs proteins reveal substance P binding mode and unique activation features by Thom, Cristian, Ehrenmann, Janosch, Vacca, Santiago, Waltenspühl, Yann, Schöppe, Jendrik, Medalia, Ohad, Plückthun, Andreas

“…Neuropeptide-bound NK 1 R:G protein complex structures explain mechanisms ranging from insurmountable antagonism to activation. The neurokinin 1 receptor (NK 1…”
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Structures of neurokinin 1 receptor in complex with G q and G s proteins reveal substance P binding mode and unique activation features by Thom, Cristian, Ehrenmann, Janosch, Vacca, Santiago, Waltenspühl, Yann, Schöppe, Jendrik, Medalia, Ohad, Plückthun, Andreas

“…The neurokinin 1 receptor (NK R) is involved in inflammation and pain transmission. This pathophysiologically important G protein–coupled receptor is…”
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