Search Results - "Thollon, C"

Use‐dependent inhibition of hHCN4 by ivabradine and relationship with reduction in pacemaker activity by Thollon, C, Bedut, S, Villeneuve, N, Cogé, F, Piffard, L, Guillaumin, J‐P, Brunel‐Jacquemin, C, Chomarat, P, Boutin, J‐A, Peglion, J‐L, Vilaine, J‐P

“…Background and purpose: Ivabradine, a specific and use‐dependent I f inhibitor, exerts anti‐ischaemic activity purely by reducing heart rate. The aim of this…”
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Role of gap junctions in the responses to EDHF in rat and guinea‐pig small arteries by Edwards, G, Félétou, M, Gardener, M J, Thollon, C, Vanhoutte, P M, Weston, A H

“…In guinea‐pig internal carotid arteries with an intact endothelium, acetylcholine (10 μM) and levcromakalim (10 μM) each hyperpolarized the smooth muscle…”
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Role of gap junctions and EETs in endothelium‐dependent hyperpolarization of porcine coronary artery by Edwards, G, Thollon, C, Gardener, M J, Félétou, M, Vilaine, J ‐P, Vanhoutte, P M, Weston, A H

“…The effects of endothelium‐derived hyperpolarizing factor (EDHF: elicited using substance P or bradykinin) were compared with those of 11,12‐EET in pig…”
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Electrophysiological effects of S 16257, a novel sino‐atrial node modulator, on rabbit and guinea‐pig cardiac preparations: comparison with UL‐FS 49 by Thollon, Catherine, Cambarrat, Christine, Vian, Joël, Prost, Jean‐François, Peglion, Jean Louis, Vilaine, Jean Paul

“…1 S 16257 is a new bradycardic agent. Its electropharmacological profile has been compared to that of the known bradycardic compound UL‐FS 49 (Zatebradine)…”
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Cannabinoid CB1 receptor and endothelium‐dependent hyperpolarization in guinea‐pig carotid, rat mesenteric and porcine coronary arteries by Chataigneau, T, Félétou, M, Thollon, C, Villeneuve, N, Vilaine, J‐ P., Duhault, J, Vanhoutte, P M.

“…1 The purpose of these experiments was to determine whether or not the endothelium‐dependent hyperpolarizations of the vascular smooth muscle cells (observed…”
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Hypertrophy induced alteration of action potential and effects of the inhibition of angiotensin converting enzyme by perindopril in infarcted rat hearts by Thollon, C, Kreher, P, Charlon, V, Rossi, A

“…Not much is known about alterations in electrical activity in the healthy part of a heart made hypertrophic as a result of local ischaemia, yet such an…”
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KEY ROLE OF TRPC3 CHANNELS IN CALCIUM HOMEOSTASIS ALTERATION RELATED TO NO DEFICIENCY IN AGED PORCINE ENDOTHELIAL CELLS by Banquet, S, Bourguignon, MP, Garry, A, Royere, E, Gosgnach, W, Thollon, C, Villeneuve, N, Vilaine, JP

“…Abstract only NO controls the activity of canonical transient receptor potential channel (TRPC) in endothelial cells. Our group already provided evidences that…”
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Altered electrical response to caffeine exposure in hypertrophied rat myocardium by Thollon, C, Kreher, P

“…We investigated the electrophysiological effects of cardiac hypertrophy induced by different experimental models. Comparison of the action potentials of…”
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REDUCED NO BIOAVAILABILITY, OXIDATIVE STRESS AND ALTERATION OF CALCIUM HOMEOSTASIS IN VASCULAR ENDOTHELIUM FROM DIABETIC MICE by Banquet, S, Bourguignon, MP, Garry, A, Royere, E, Crespo, C, Lapret, I, Simonet, S, Gosgnach, W, Thollon, C, Villeneuve, N, Vilaine, JP

“…Abstract only Endothelial dysfunction is a major risk factor for vascular complications associated with diabetes. The purpose of this study was to evaluate the…”
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Cannabinoid CB 1 receptor and endothelium‐dependent hyperpolarization in guinea‐pig carotid, rat mesenteric and porcine coronary arteries by Chataigneau, T, Félétou, M, Thollon, C, Villeneuve, N, Vilaine, J‐ P., Duhault, J, Vanhoutte, P M.

“…The purpose of these experiments was to determine whether or not the endothelium‐dependent hyperpolarizations of the vascular smooth muscle cells (observed in…”
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Potassium ions and endothelium‐derived hyperpolarizing factor in guinea‐pig carotid and porcine coronary arteries by Quignard, Jean‐François, Félétou, Michel, Thollon, Catherine, Vilaine, Jean‐Paul, Duhault, Jacques, Vanhoutte, Paul M

“…Experiments were designed to determine in two arteries (the guinea‐pig carotid and the porcine coronary arteries) whether or not the endothelium‐derived…”
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Consequences of reduced production of NO on vascular reactivity of porcine coronary arteries after angioplasty: importance of EDHF by Thollon, Catherine, Fournet‐Bourguignon, Marie Pierre, Saboureau, Delphine, Lesage, Ludovic, Reure, Hélène, Vanhoutte, Paul M, Vilaine, Jean Paul

“…The consequences of the reduced production of nitric oxide (NO) by cells from regenerated endothelium were investigated by measuring membrane potential of…”
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Procoralan, a new selective If current inhibitor by Vilaine, J.P., Thollon, C., Villenueve, N., Peglion, J.L.

“…Procoralan (S 16257-2) is a selective inhibitor of the pacemaker If current. It reduces in vitro the spontaneous beating rate of the sinus node by slowing the…”
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Stereospecific in vitro and in vivo effects of the new sinus node inhibitor (+)-S 16257 by Thollon, Catherine, Bidouard, Jean-Pierre, Cambarrat, Christine, Lesage, Ludovic, Reure, Hélène, Delescluse, Isabelle, Vian, Joël, Peglion, Jean-Louis, Vilaine, Jean-Paul

“…The effects of the two isomers, (+)-S 16257 and (−)-S 16260, of a new bradycardic agent, (±)-S 15544 (7,8-dimethoxy 3-{3-{[(4,5-dimethoxybenzocyclobutan-1-yl)…”
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Alteration of Endothelium-Dependent Hyperpolarizations in Porcine Coronary Arteries With Regenerated Endothelium by Thollon, Catherine, Bidouard, Jean P, Cambarrat, Christine, Delescluse, Isabelle, Villeneuve, Nicole, Vanhoutte, Paul M, Vilaine, Jean P

“…The present study was designed to test the ability of regenerated endothelium to evoke endothelium-dependent hyperpolarizations. Hyperpolarizations induced by…”
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Nature of the cardiomyocyte injury induced by lipid hydroperoxides by Thollon, C, Iliou, J P, Cambarrat, C, Robin, F, Vilaine, J P

“…As a result of oxidative stress to membrane lipid matrix, the peroxidation of polyunsaturated fatty acids induced the transient formation of lipid…”
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Monohydroperoxidized fatty acids but not 4-hydroxynonenal induced acute cardiac cell damage by Iliou, Jean-Pierre, Thollon, Catherine, Villeneuve, Nicole, Robin, Frederic, Cambarrat, Christine, Jacquemin, Christine, Vilaine, Jean-Paul

“…Unsaturated fatty acids constitutive of cardiac membranal lipid matrix are one of the primary targets for reactive oxygen species generated during…”
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Protective effect of S12340 on cardiac cells exposed to oxidative stress by Iliou, J P, Thollon, C, Robin, F, Cambarrat, C, Guillonneau, C, Régnier, G, Lenaers, A, Vilaine, J P

“…Oxidative stress induced by reactive oxygen species is one aspect of the deleterious mechanisms involved in myocardial post-ischemic reperfusion injury. The…”
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Absence, in the hypertrophied rat heart caused by aortocaval fistula, of several metabolic and electrophysiological changes seen in other models of hypertrophy by Thollon, C, Aussedat, J, Verdetti, J, Kreher, P

“…In this work, we compared the electrophysiological and metabolic parameters of a volume overload model of cardiac hypertrophy (aorto-caval fistula) with those…”
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