Search Results - "Thodey, Kate"

A microbial biomanufacturing platform for natural and semisynthetic opioids by Thodey, Kate, Galanie, Stephanie, Smolke, Christina D

“…Metabolic engineering of yeast to incorporate plant and bacterial enzymes that construct and decorate morphine, along with spatial engineering to enable a…”
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Complete biosynthesis of opioids in yeast by Galanie, Stephanie, Thodey, Kate, Trenchard, Isis J., Interrante, Maria Filsinger, Smolke, Christina D.

“…Opioids are the primary drugs used in Western medicine for pain management and palliative care. Farming of opium poppies remains the sole source of these…”
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Complete biosynthesis of noscapine and halogenated alkaloids in yeast by Li, Yanran, Li, Sijin, Thodey, Kate, Trenchard, Isis, Cravens, Aaron, Smolke, Christina D.

“…Microbial biosynthesis of plant natural products from simple building blocks is a promising approach toward scalable production and modification of high-value…”
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De novo production of the key branch point benzylisoquinoline alkaloid reticuline in yeast by Trenchard, Isis J., Siddiqui, Michael S., Thodey, Kate, Smolke, Christina D.

“…Microbial biosynthesis for plant-based natural products, such as the benzylisoquinoline alkaloids (BIAs), has the potential to address limitations in…”
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Applications of genetically-encoded biosensors for the construction and control of biosynthetic pathways by Michener, Joshua K., Thodey, Kate, Liang, Joe C., Smolke, Christina D.

“…Cells are filled with biosensors, molecular systems that measure the state of the cell and respond by regulating host processes. In much the same way that an…”
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Global gene expression analysis of apple fruit development from the floral bud to ripe fruit by Janssen, Bart J, Thodey, Kate, Schaffer, Robert J, Alba, Rob, Balakrishnan, Lena, Bishop, Rebecca, Bowen, Judith H, Crowhurst, Ross N, Gleave, Andrew P, Ledger, Susan, McArtney, Steve, Pichler, Franz B, Snowden, Kimberley C, Ward, Shayna

“…Apple fruit develop over a period of 150 days from anthesis to fully ripe. An array representing approximately 13000 genes (15726 oligonucleotides of 45-55…”
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rapid transcriptional activation is induced by the dormancy-breaking chemical hydrogen cyanamide in kiwifruit (Actinidia deliciosa) buds by Walton, Eric F, Wu, Rong-Mei, Richardson, Annette C, Davy, Marcus, Hellens, Roger P, Thodey, Kate, Janssen, Bart J, Gleave, Andrew P, Rae, Georgina M, Wood, Marion, Schaffer, Robert J

“…Budbreak in kiwifruit (Actinidia deliciosa) can be poor in locations that have warm winters with insufficient winter chilling. Kiwifruit vines are often…”
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Advancing secondary metabolite biosynthesis in yeast with synthetic biology tools by Siddiqui, Michael S., Thodey, Kate, Trenchard, Isis, Smolke, Christina D.

“…Abstract Secondary metabolites are an important source of high-value chemicals, many of which exhibit important pharmacological properties. These valuable…”
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A microbial biomanufacturing platform for natural and semi-synthetic opiates by Thodey, Kate, Galanie, Stephanie, Smolke, Christina D.

“…Opiates and related molecules are medically essential, but their production via field cultivation of opium poppy Papaver somniferum leads to supply…”
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Glucose Elevates NITRATE TRANSPORTER2.1 Protein Levels and Nitrate Transport Activity Independently of Its HEXOKINASE1-Mediated Stimulation of NITRATE TRANSPORTER2.1 Expression by de Jong, Femke, Thodey, Kate, Lejay, Laurence V., Bevan, Michael W.

“…Mineral nutrient uptake and assimilation is closely coordinated with the production of photosynthate to supply nutrients for growth. In Arabidopsis…”
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Genomics Approach Reveals That Aroma Production in Apple Is Controlled by Ethylene Predominantly at the Final Step in Each Biosynthetic Pathway by Schaffer, Robert J, Friel, Ellen N, Souleyre, Edwige J.F, Bolitho, Karen, Thodey, Kate, Ledger, Susan, Bowen, Judith H, Ma, Jun-Hong, Nain, Bhawana, Cohen, Daniel, Gleave, Andrew P, Crowhurst, Ross N, Janssen, Bart J, Yao, Jia-Long, Newcomb, Richard D

“…Ethylene is the major effector of ripening in many fleshy fruits. In apples (Malus x domestica) the addition of ethylene causes a climacteric burst of…”
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Bringing It Together with RNA by Thodey, Kate, Smolke, Christina D.

“…Synthetic RNA nanostructures can direct biochemical pathways in cells. The biochemical reactions that underlie life have evolved to be spatially organized…”
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Glucose Elevates NITRATE TRANSPORTER2.1 Protein Levels and Nitrate Transport Activity Independently of Its HEXOKINASE1-Mediated Stimulation of NITRATE TRANSPORTER2.1 Expression1[W][OPEN] by de Jong, Femke, Thodey, Kate, Lejay, Laurence V., Bevan, Michael W.

“…Independent mechanisms link photosynthate availability with nitrate uptake and assimilation into amino acids . Mineral nutrient uptake and assimilation is…”
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Cell biology. Bringing it together with RNA by Thodey, Kate, Smolke, Christina D

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Antioxidant activities of extracts from traditional Maori food plants by Gould, Kevin S., Thodey, Kate, Philpott, Martin, Ferguson, Lynnette R.

“…New Zealand plants reportedly used as food by the early Maori may have been rich in low molecular weight antioxidants. To test this possibility,…”
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