Search Results - "Thode, Silke"

Aberrant Patterning of Neuromuscular Synapses in Choline Acetyltransferase-Deficient Mice by Brandon, Eugene P, Lin, Weichun, D'Amour, Kevin A, Pizzo, Donald P, Dominguez, Bertha, Sugiura, Yoshie, Thode, Silke, Ko, Chien-Ping, Thal, Leon J, Gage, Fred H, Lee, Kuo-Fen

“…In this study we examined the developmental roles of acetylcholine (ACh) by establishing and analyzing mice lacking choline acetyltransferase (ChAT), the…”
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Development of a large-scale chemogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action by Ganter, Brigitte, Tugendreich, Stuart, Pearson, Cecelia I., Ayanoglu, Eser, Baumhueter, Susanne, Bostian, Keith A., Brady, Lindsay, Browne, Leslie J., Calvin, John T., Day, Gwo-Jen, Breckenridge, Naiomi, Dunlea, Shane, Eynon, Barrett P., Furness, L. Mike, Ferng, Joe, Fielden, Mark R., Fujimoto, Susan Y., Gong, Li, Hu, Christopher, Idury, Radha, Judo, Michael S.B., Kolaja, Kyle L., Lee, May D., McSorley, Christopher, Minor, James M., Nair, Ramesh V., Natsoulis, Georges, Nguyen, Peter, Nicholson, Simone M., Pham, Hang, Roter, Alan H., Sun, Dongxu, Tan, Siqi, Thode, Silke, Tolley, Alexander M., Vladimirova, Antoaneta, Yang, Jian, Zhou, Zhiming, Jarnagin, Kurt

“…Successful drug discovery requires accurate decision making in order to advance the best candidates from initial lead identification to final approval…”
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Novel inhibitors of poly(ADP-ribose) polymerase/PARP1 and PARP2 identified using a cell-based screen in yeast by PERKINS, Ed, DONGXU SUN, YEH, Elaine, THODE, Silke, JARNAGIN, Kurt, JAIN, Ajay, MORGANS, David, MELESE, Teri, NGUYEN, Allen, TULAC, Suzana, FRANCESCO, Michelle, TAVANA, Homa, NGUYEN, Hieu, TUGENDREICH, Stuart, BARTHMAIER, Peter, COUTO, Joe

“…Multicellular organisms must have means of preserving their genomic integrity or face catastrophic consequences such as uncontrolled cell proliferation or…”
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A novel pathway of DNA end-to-end joining by Thode, S, Schäfer, A, Pfeiffer, P, Vielmetter, W

“…Repair mechanisms related to illegitimate recombination can join nonhomologous DNA ends that terminate as protruding single strands (PSS). Here we analyze in…”
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Mechanisms of overlap formation in nonhomologous DNA end joining by PFEIFFER, P, THODE, S, HANCKE, J, VIELMETTER, W

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Immortalized Human Dorsal Root Ganglion Cells Differentiate into Neurons with Nociceptive Properties by Raymon, Heather K, Thode, Silke, Zhou, Jiuying, Friedman, Glenn C, Pardinas, Jose R, Barrere, Christian, Johnson, Randolph M, Sah, Dinah W. Y

“…A renewable source of human sensory neurons would greatly facilitate basic research and drug development. We had established previously conditionally…”
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Motoneuron differentiation of immortalized human spinal cord cell lines by Li, Ronghao, Thode, Silke, Zhou, Jiuying, Richard, Normand, Pardinas, Jose, Rao, Mahendra S., Sah, Dinah W.Y.

“…Human motoneuron cell lines will be valuable tools for spinal cord research and drug discovery. To create such cell lines, we immortalized NCAM+/neurofilament+…”
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Resolution and conservation of mismatches in DNA end joining by Pfeiffer, P, Thode, S, Hancke, J, Keohavong, P, Thilly, W G

“…DNA end joining is a major pathway for the elimination of double-strand breaks from chromosomal DNA of higher eucaryotic cells. Extracts of Xenopus laevis eggs…”
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Mechanisms of Overlap Formation in Nonhomologous DNA End Joining by Pfeiffer, Petra, Thode, Silke, Hancke, Juliane, Vielmetter, Walter

“…Rejoining of nonhomologous DNA termini plays a central role in processes of illegitimate recombination. In Xenopus egg extracts, DNA ends with noncomplementary…”
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