Search Results - "Thirunavukarasou, Anand"
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CRISPR/Cas-Based Modifications for Therapeutic Applications: A Review
Published in Molecular biotechnology (01-04-2022)“…The CRISPR–Cas genome editing system is an intrinsic property of a bacteria-based immune system. This employs a guide RNA to detect and cleave the…”
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Bibliometric analysis of artificial intelligence in healthcare research: Trends and future directions
Published in Future healthcare journal (01-09-2024)“…The presence of artificial intelligence (AI) in healthcare is a powerful and game-changing force that is completely transforming the industry as a whole. Using…”
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Transforming oral cancer care: The promise of deep learning in diagnosis
Published in Oral oncology reports (01-06-2024)“…The diagnosis and treatment of oral cancer present significant challenges, including delayed diagnosis at advanced stages and limited access to healthcare…”
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Exopolysaccharides Derived from Probiotic Bacteria and their Health Benefits
Published in Journal of pure & applied microbiology : an international research journal of microbiology (01-03-2023)“…Probiotic bacteria are producers of secretory products such as bacteriocins and polysaccharides. Both homopolymeric and heteropolymeric exopolysaccharides…”
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Exploring major bioactive phytocompounds of Ficus racemosa and its key pharmacological activities
Published in Journal of King Saud University. Science (01-01-2024)“…Ficus racemosa has long been used as a treatment for bacterial and fungal infections by people in India. The search for a safe alternative therapy from plant…”
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Identifying Potent Fat Mass and Obesity-Associated Protein Inhibitors Using Deep Learning-Based Hybrid Procedures
Published in BioMedInformatics (01-02-2024)“…The fat mass and obesity-associated (FTO) protein catalyzes metal-dependent modifications of nucleic acids, namely the demethylation of methyl adenosine inside…”
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E3 ligases: a potential multi-drug target for different types of cancers and neurological disorders
Published in Future medicinal chemistry (01-01-2022)“…Ubiquitylation is a posttranslational modification of proteins that is necessary for a variety of cellular processes. E1 ubiquitin activating enzyme, E2…”
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Neurogranin in Alzheimer's Disease: Roles in synaptic function, pathology, and potential as a diagnostic biomarker
Published in AIMS molecular science (2024)“…Postsynaptic protein neurogranin (Ng), which plays a role in synaptic plasticity, learning, and memory, has been identified as the candidate biomarker of…”
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E3 ubiquitin ligase Cullin4B mediated polyubiquitination of p53 for its degradation
Published in Molecular and cellular biochemistry (01-05-2014)“…Controlled protein ubiquitination through E3 ubiquitin ligases and degradation via 26S proteasome machinery is required for orderly progression through cell…”
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Advancement of targeted protein degradation strategies as therapeutics for undruggable disease targets
Published in Future medicinal chemistry (01-05-2023)“…Targeted protein degradation (TPD) aids in developing novel bifunctional small-molecule degraders and eliminates proteins of interest. The TPD approach shows…”
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Cullin 4A and 4B ubiquitin ligases interact with γ-tubulin and induce its polyubiquitination
Published in Molecular and cellular biochemistry (01-03-2015)“…Regulated polyubiquitination is a key step for controlling protein degradation and maintaining proper balance between the proliferation of normal and…”
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Cullin 4A and 4B ubiquitin ligases interact with [gamma]-tubulin and induce its polyubiquitination
Published in Molecular and cellular biochemistry (01-03-2015)“…Regulated polyubiquitination is a key step for controlling protein degradation and maintaining proper balance between the proliferation of normal and…”
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