Search Results - "Thirunarayanan, Nanthakumar"

Toll-Like Receptor Signaling in Small Intestinal Epithelium Promotes B-Cell Recruitment and IgA Production in Lamina Propria by Shang, Limin, Fukata, Masayuki, Thirunarayanan, Nanthakumar, Martin, Andrea P, Arnaboldi, Paul, Maussang, David, Berin, Cecilia, Unkeless, Jay C, Mayer, Lloyd, Abreu, Maria T, Lira, Sergio A

“…Background & Aims: Several lines of evidence support a role for Toll-like receptor (TLR) signaling to protect the intestine from pathogenic infection. We…”
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The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice by Bongers, Gerold, Maussang, David, Muniz, Luciana R, Noriega, Vanessa M, Fraile-Ramos, Alberto, Barker, Nick, Marchesi, Federica, Thirunarayanan, Nanthakumar, Vischer, Henry F, Qin, Lihui, Mayer, Lloyd, Harpaz, Noam, Leurs, Rob, Furtado, Glaucia C, Clevers, Hans, Tortorella, Domenico, Smit, Martine J, Lira, Sergio A

“…US28 is a constitutively active chemokine receptor encoded by CMV (also referred to as human herpesvirus 5), a highly prevalent human virus that infects a…”
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MicroRNA-34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHV-vGPCR by Krause, Claudia J, Popp, Oliver, Thirunarayanan, Nanthakumar, Dittmar, Gunnar, Lipp, Martin, Müller, Gerd

“…The Kaposi's sarcoma-associated herpesvirus (KSHV)-encoded chemokine receptor vGPCR acts as an oncogene in Kaposi's sarcomagenesis. Until now, the molecular…”
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A Role for the Epidermal Growth Factor Receptor Signaling in Development of Intestinal Serrated Polyps in Mice and Humans by Bongers, Gerold, Muniz, Luciana R, Pacer, Michelle E, Iuga, Alina C, Thirunarayanan, Nanthakumar, Slinger, Erik, Smit, Martine J, Reddy, E. Premkumar, Mayer, Lloyd, Furtado, Glaucia C, Harpaz, Noam, Lira, Sergio A

“…Background & Aims Epithelial cancers can be initiated by activating mutations in components of the mitogen-activated protein kinase signaling pathway such as…”
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Taltirelin is a superagonist at the human thyrotropin-releasing hormone receptor by Thirunarayanan, Nanthakumar, Raaka, Bruce M, Gershengorn, Marvin C

“…Taltirelin (TAL) is a thyrotropin-releasing hormone (TRH) analog that is approved for use in humans in Japan. In this study, we characterized TAL binding to…”
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Thyrotropin-releasing hormone receptor type 1 (TRH-R1), not TRH-R2, primarily mediates taltirelin actions in the CNS of mice by Thirunarayanan, Nanthakumar, Nir, Eshel A, Raaka, Bruce M, Gershengorn, Marvin C

“…Thyrotropin-releasing hormone receptor type 2 (TRH-R2), not TRH-R1, has been proposed to mediate the CNS effects of TRH and its more effective analog…”
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Thyrotropin-Releasing Hormone Receptor Type I (TRH-R1), not TRH-R2, Primarily Mediates Taltirelin Actions in the CNS of Mice by THIRUNARAYANAN, Nanthakumar, NIR, Eshel A, RAAKA, Bruce M, GERSHENGORN, Marvin C

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Expression of the Chemokine Binding Protein M3 Promotes Marked Changes in the Accumulation of Specific Leukocytes Subsets Within the Intestine by Shang, Limin, Thirunarayanan, Nanthakumar, Viejo–Borbolla, Abel, Martin, Andrea P, Bogunovic, Milena, Marchesi, Federica, Unkeless, Jay C, Ho, Yin, Furtado, Glaucia C, Alcami, Antonio, Merad, Miriam, Mayer, Lloyd, Lira, Sergio A

“…Background & Aims Chemokines are small proteins that direct leukocyte trafficking under homeostatic and inflammatory conditions. We analyzed the differential…”
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The cytomegalovirus-encoded chemoking receptor US28 promotes intestinal neoplasia in transgenic mice by Bongers, Gerold, Maussang, David, Muniz, Luciana R, Noriega, Vanessa M, Fraile-Ramos, Alberto, Barker, Nick, Marchesi, Federica, Thirunarayanan, Nanthakumar, Vischer, Henry F, Qin, Lihui, Mayer, Lloyd, Harpaz, Noam, Leurs, Rob, Furtado, Glaucia C, Clevers, Hans, Tortorella, Domenico, Smit, Martine J, Lira, Sergio A

“…US28 is a constitutively active chemokine receptor encoded by CMV (also referred to as human herpesvirus 5), a highly prevalent human virus that infects a…”
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TLR signaling in small intestinal epithelium promotes B cell recruitment and IgA production in lamina propria by Shang, Limin, Fukata, Masayuki, Thirunarayanan, Nanthakumar, Martin, Andrea P., Arnaboldi, Paul, Maussang, David, Berin, Cecilia, Unkeless, Jay C., Mayer, Lloyd, Abreu, Maria T., Lira, Sergio A.

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Attenuation of TNF-driven murine ileitis by intestinal expression of the viral immunomodulator CrmD by Viejo-Borbolla, A, Martin, A P, Muniz, L R, Shang, L, Marchesi, F, Thirunarayanan, N, Harpaz, N, Garcia, R A, Apostolaki, M, Furtado, G C, Mayer, L, Kollias, G, Alcami, A, Lira, S A

“…Tumor necrosis factor α (TNFα) is a key pathogenic factor in Crohn's disease and rheumatoid arthritis. TNF ΔARE mice express high levels of TNFα and present…”
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