Search Results - "Thiruchelvam, Paul"

Meta-analysis Comparing Fluorescence Imaging with Radioisotope and Blue Dye-Guided Sentinel Node Identification for Breast Cancer Surgery by Kedrzycki, Martha S., Leiloglou, Maria, Ashrafian, Hutan, Jiwa, Natasha, Thiruchelvam, Paul T. R., Elson, Daniel S., Leff, Daniel R.

“…Introduction Conventional methods for axillary sentinel lymph node biopsy (SLNB) are fraught with complications such as allergic reactions, skin tattooing,…”
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American Society of Breast Surgeons’ Practice Patterns for Patients at Risk and Affected by Breast Cancer-Related Lymphedema by DeSnyder, Sarah M., Yi, Min, Boccardo, Francesco, Feldman, Sheldon, Klimberg, V. Suzanne, Smith, Mark, Thiruchelvam, Paul T. R., McLaughlin, Sarah

“…Background In 2017, the American Society of Breast Surgeons (ASBrS) published expert panel recommendations for patients at risk for breast cancer-related…”
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Considerations for Clinicians in the Diagnosis, Prevention, and Treatment of Breast Cancer-Related Lymphedema, Recommendations from an Expert Panel: Part 2: Preventive and Therapeutic Options by McLaughlin, Sarah A., DeSnyder, Sarah M., Klimberg, Suzanne, Alatriste, Michael, Boccardo, Francesco, Smith, Mark L., Staley, Alicia C., Thiruchelvam, Paul T. R., Hutchison, Nancy A., Mendez, Jane, MacNeill, Fiona, Vicini, Frank, Rockson, Stanley G., Feldman, Sheldon M.

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Primary radiotherapy and deep inferior epigastric perforator flap reconstruction for patients with breast cancer (PRADA): a multicentre, prospective, non-randomised, feasibility study by Thiruchelvam, Paul T R, Leff, Daniel R, Godden, Amy R, Cleator, Susan, Wood, Simon H, Kirby, Anna M, Jallali, Navid, Somaiah, Navita, Hunter, Judith E, Henry, Francis P, Micha, Aikaterini, O'Connell, Rachel L, Mohammed, Kabir, Patani, Neill, Tan, Melissa L H, Gujral, Dorothy, Ross, Gillian, James, Stuart E, Khan, Aadil A, Rusby, Jennifer E, Hadjiminas, Dimitri J, MacNeill, Fiona A, Thiruchelvam, Paul TR, Leff, Daniel R, Godden, Amy R, Cleator, Susan, Wood, Simon H, Kirby, Anna M, Somaiah, Navita, Patani, Neill, Gujral, Dorothy, Ross, Gillian, James, Stuart, Khan, Aadil, Rusby, Jennifer E, Hadjiminas, Dimitri, MacNeill, Fiona A

“…Radiotherapy before mastectomy and autologous free-flap breast reconstruction can avoid adverse radiation effects on healthy donor tissues and delays to…”
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The Impact of Temporal Variation in Indocyanine Green Administration on Tumor Identification During Fluorescence Guided Breast Surgery by Kedrzycki, Martha S., Leiloglou, Maria, Chalau, Vadzim, Chiarini, Nicolas, Thiruchelvam, Paul T. R., Hadjiminas, Dimitri J., Hogben, Katy R., Rashid, Faiza, Ramakrishnan, Rathi, Darzi, Ara W., Elson, Daniel S., Leff, Daniel R.

“…Background On average, 21% of women in the USA treated with Breast Conserving Surgery (BCS) undergo a second operation because of close positive margins. Tumor…”
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Indocyanine green fluorescence image processing techniques for breast cancer macroscopic demarcation by Leiloglou, Maria, Kedrzycki, Martha S., Chalau, Vadzim, Chiarini, Nicolas, Thiruchelvam, Paul T. R., Hadjiminas, Dimitri J., Hogben, Katy R., Rashid, Faiza, Ramakrishnan, Rathi, Darzi, Ara W., Leff, Daniel R., Elson, Daniel S.

“…Re-operation due to disease being inadvertently close to the resection margin is a major challenge in breast conserving surgery (BCS). Indocyanine green (ICG)…”
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Pre-operative Radiotherapy And Deep Inferior Epigastric Artery Perforator (DIEP) flAp study (PRADA): Aesthetic outcome and patient satisfaction at one year by Godden, Amy R., Micha, Aikaterini, O'Connell, Rachel L., Mohammed, Kabir, Kirby, Anna M., Thiruchelvam, Paul T.R., Leff, Daniel R., MacNeill, Fiona A., Rusby, Jennifer E., Cleator, Susan, Godden, Amy, Gujral, Dorothy, Hadjiminas, Dimitri, James, Stuart E., Khan, Aadil, Kirby, Anna M., Leff, Daniel R., MacNeill, Fiona A., Patani, Neill, Ross, Gillian, Rusby, Jennifer E., Somaiah, Navita, Thiruchelvam, Paul TR, Wood, Simon H

“…The optimal combination of radiotherapy and breast reconstruction has not yet been defined. Post-mastectomy radiotherapy (PMRT) has deleterious effects on…”
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Assessment of Technical Skills in Axillary Lymph Node Dissection by Muthuswamy, Keerthini, Fisher, Rebecca, Mavroveli, Stella, Petrou, Fotis, Khawar, Sabrina, Amlani, Ashik, Hanna, George B., Hadjiminas, Dimitri J., Thiruchelvam, Paul T. R., Leff, Daniel R.

“…OBJECTIVE:A simulator to enable safe practice and assessment of ALND has been designed, and face, content and construct validity has been investigated. SUMMARY…”
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The liver receptor homolog-1 regulates estrogen receptor expression in breast cancer cells by Thiruchelvam, Paul T. R., Lai, Chun-Fui, Hua, Hui, Thomas, Ross S., Hurtado, Antoni, Hudson, William, Bayly, Andrew R., Kyle, Fiona J., Periyasamy, Manikandan, Photiou, Andrew, Spivey, Alan C., Ortlund, Eric A., Whitby, Richard J., Carroll, Jason S., Coombes, R. Charles, Buluwela, Laki, Ali, Simak

“…Estrogen receptor-α (ER) is expressed in the great majority of breast cancers, and the inhibition of ER action is a key part of breast cancer treatment. The…”
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ASO Visual Abstract: American Society of Breast Surgeons Practice Patterns for Patients At-risk and Affected by Breast Cancer-Related Lymphedema by DeSnyder, Sarah M., Yi, Min, Boccardo, Francesco, Feldman, Sheldon, Klimberg, V. Suzanne, Smith, Mark, Thiruchelvam, Paul T. R., McLaughlin, Sarah

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The feasibility and safety of immediate breast reconstruction in the COVID-19 era by Jallali, Navid, Hunter, Judith E., Henry, Francis P., Wood, Simon H., Hogben, Katy, Almufti, Ragheed, Hadjiminas, Dimitri, Dunne, Jonathan, Thiruchelvam, Paul T.R., Leff, Daniel R.

“…The coronavirus disease-2019 pandemic has had a significant impact on the delivery of surgical services, particularly reconstructive surgery. This article…”
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ASO Visual Abstract: The Impact of Temporal Variation in Indocyanine Green Administration on Tumor Identification During Fluorescence-Guided Breast Surgery by Kedrzycki, Martha S., Leiloglou, Maria, Chalau, Vadzim, Chiarini, Nicolas, Thiruchelvam, Paul T. R., Hadjiminas, Dimitri J., Hogben, Katy R., Rashid, Faiza, Ramakrishnan, Rathi, Darzi, Ara W., Elson, Daniel S., Leff, Daniel R.

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estrogen receptor-α-induced microRNA signature regulates itself and its transcriptional response by Castellano, Leandro, Giamas, Georgios, Jacob, Jimmy, Coombes, R. Charles, Lucchesi, Walter, Thiruchelvam, Paul, Barton, Geraint, Jiao, Long R, Wait, Robin, Waxman, Jonathan, Hannon, Gregory J, Stebbing, Justin

“…Following estrogenic activation, the estrogen receptor-α (ERα) directly regulates the transcription of target genes via DNA binding. MicroRNAs (miRNAs)…”
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Pervasive genetic testing by Thiruchelvam, Paul T R, Fisher, Carla S, Leff, Daniel R, Domchek, Susan M

“…Guidelines stipulate that a personal or family history of breast cancer be present for an individual to be eligible for genetic testing.12,14 The family…”
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Post-mastectomy breast reconstruction by Thiruchelvam, Paul T R, McNeill, Fiona, Jallali, Navid, Harris, Paul, Hogben, Katy

“…Breast cancer is the most common cancer in women, with almost 1.38 million new cases a year worldwide; it accounts for 23% of all cancers and 14% of deaths…”
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Patient-level costs of staged unilateral versus immediate bilateral symmetrization mammoplasty in breast-conserving surgery by Grant, Yasmin, Thiruchelvam, Paul T R, Kovacevic, Lana, Mossialos, Elias, Al-Mufti, Ragheed, Hogben, Katy, Hadjiminas, Dimitri J, Leff, Daniel R

“…Following therapeutic mammoplasty (TM), the contralateral breast may require a later balancing procedure to optimize shape and symmetry. The alternative is to…”
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Co-regulated gene expression by oestrogen receptor α and liver receptor homolog-1 is a feature of the oestrogen response in breast cancer cells by Lai, Chun-Fui, Flach, Koen D, Alexi, Xanthippi, Fox, Stephen P, Ottaviani, Silvia, Thiruchelvam, Paul T R, Kyle, Fiona J, Thomas, Ross S, Launchbury, Rosalind, Hua, Hui, Callaghan, Holly B, Carroll, Jason S, Charles Coombes, R, Zwart, Wilbert, Buluwela, Laki, Ali, Simak

“…Oestrogen receptor α (ERα) is a nuclear receptor that is the driving transcription factor expressed in the majority of breast cancers. Recent studies have…”
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The prevention and treatment of breast cancer- related lymphedema: A review by McEvoy, Maureen P, Gomberawalla, Ameer, Smith, Mark, Boccardo, Francesco M, Holmes, Dennis, Djohan, Risal, Thiruchelvam, Paul, Klimberg, Suzanne, Dietz, Jill, Feldman, Sheldon

“…Breast cancer- related lymphedema (BCRL) affects about 3 to 5 million patients worldwide, with about 20,000 per year in the United States. As breast cancer…”
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Renal transplantation by Thiruchelvam, Paul T R, Willicombe, Michelle, Hakim, Nadey, Taube, David, Papalois, Vassilios

“…SUMMARY POINTS The global burden of end stage renal disease is increasing Renal transplantation increases patient survival and quality of life and reduces…”
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Transient over-expression of estrogen receptor-α in breast cancer cells promotes cell survival and estrogen-independent growth by Tolhurst, Robert S., Thomas, Ross S., Kyle, Fiona J., Patel, Hetal, Periyasamy, Manikandan, Photiou, Andrew, Thiruchelvam, Paul T. R., Lai, Chun-Fui, Al-sabbagh, Marwa, Fisher, Rosemary A., Barry, Sayka, Crnogorac-Jurcevic, Tatjana, Martin, Lesley-Ann, Dowsett, Mitch, Charles Coombes, R., Kamalati, Tahereh, Ali, Simak, Buluwela, Laki

“…Estrogen receptor-α (ERα) positive breast cancer frequently responds to inhibitors of ERα activity, such as tamoxifen, and/or to aromatase inhibitors that…”
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