Search Results - "Thirstrup, K"

Regulation of the Bcas1 and Baiap3 transcripts in the subthalamic nucleus in mice recovering from MPTP toxicity by Lauridsen, J.B., Johansen, J.L., Rekling, J.C., Thirstrup, K., Moerk, A., Sager, T.N.

“…► Behavioral recovery was identified in mice following MPTP toxicity. ► Striatal dopamine levels showed no recovery in mice following MPTP toxicity. ►…”
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Analysis of selective binding epitopes for the kappa-opioid receptor antagonist nor-binaltorphimine by Hjorth, S A, Thirstrup, K, Grandy, D K, Schwartz, T W

“…The structural determinants for the selective binding of the nonpeptide opioid receptor antagonist nor-binaltorphimine (nor-BNI) to the kappa-opioid receptor…”
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Radioligand-dependent discrepancy in agonist affinities enhanced by mutations in the kappa-opioid receptor by Hjorth, S A, Thirstrup, K, Schwartz, T W

“…A series of kappa/mu receptor chimeras and a number of kappa receptors substituted in the second transmembrane segment (TM-II) were investigated using as…”
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B17Characterisation Of A Huntington's Disease Cellular Model For The Transcriptome-based Expression Analysis Of Deubiquitinating Enzymes by Rauen, M, Christensen, K, Thirstrup, K, Dantuma, N, Noerremoelle, A, Daechsel, J, Fog, K

“…BackgroundHuntington's disease (HD) displays a characteristic accumulation of mutant huntingtin (Htt) into cellular aggregates. Deficiency in protein clearance…”
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B17 Characterisation Of A Huntington's Disease Cellular Model For The Transcriptome-based Expression Analysis Of Deubiquitinating Enzymes by Rauen, M., Christensen, K., Thirstrup, K., Dantuma, N., Norremolle, A., Dachsel, J., Fog, K.

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Conversion of agonist site to metal-ion chelator site in the beta(2)-adrenergic receptor by Elling, C E, Thirstrup, K, Holst, B, Schwartz, T W

“…Previously metal-ion sites have been used as structural and functional probes in seven transmembrane receptors (7TM), but as yet all the engineered sites have…”
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Restriction fragment differential display of pediocin-resistant Listeria monocytogenes 412 mutants shows consistent overexpression of a putative β-glucoside-specific PTS system by GRAVESEN, A, WARTHOE, P, KNØCHEL, S, THIRSTRUP, K

“…Pediocin PA-1, which is a bacteriocin produced by lactic acid bacteria, has potential as a biopreservative of food. However, such use may lead to the…”
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Evidence for a Pancreatic Lipase Subfamily with New Kinetic Properties by Thirstrup, Kenneth, Verger, Robert, Carriere, Frederic

“…Several new members of the pancreatic lipase family have been reported recently, and amino acid sequence comparison reveals that this family can now be divided…”
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CHARACTERISATION OF A HUNTINGTON'S DISEASE CELLULAR MODEL FOR THE TRANSCRIPTOME-BASED EXPRESSION ANALYSIS OF DEUBIQUITINATING ENZYMES by Rauen, M, Christensen, K, Thirstrup, K, Dantuma, N, Norremolle, A, Dachsel, J, Fog, K

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Multiprotein bridging factor 1 cooperates with c-jun and is necessary for cardiac hypertrophy in vitro by Busk, Peter K, Wulf-Andersen, Linda, Strøm, Claes C, Enevoldsen, Micha, Thirstrup, Kenneth, Haunsø, Stig, Sheikh, S.øren P

“…Cardiac hypertrophy is induced by a number of stimuli and can lead to cardiomyopathy and heart failure. Cardiomyocyte hypertrophy is characterized by increased…”
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Construction of a high affinity zinc switch in the kappa-opioid receptor by Thirstrup, K, Elling, C E, Hjorth, S A, Schwartz, T W

“…Very limited structural information is available concerning the superfamily of G-protein-coupled receptors with their seven-transmembrane segments. Recently a…”
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Pancreatic Lipase Structure−Function Relationships by Domain Exchange by Carrière, Frédéric, Thirstrup, Kenneth, Hjorth, Siv, Ferrato, Francine, Nielsen, Per F, Withers-Martinez, Chrislaine, Cambillau, Christian, Boel, Esper, Thim, Lars, Verger, Robert

“…We designed chimeric mutants by exchanging the lid domains of the classical human pancreatic lipase (HPL) and the guinea pig pancreatic lipase related protein…”
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Cloning of the classical guinea pig pancreatic lipase and comparison with the lipase related protein 2 by Carrière, Frédéric, Thirstrup, Kenneth, Hjorth, Siv, Boel, Esper

“…Starting from total pancreatic mRNAs, the classical guinea pig pancreatic lipase was cloned using rapid amplification of 3' and 5' cDNA ends. Internal…”
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Conversion of agonist site to metal-ion chelator site in the beta sub(2)-adrenergic receptor by Elling, CE, Thirstrup, K, Holst, B, Schwartz, T W

“…Previously metal-ion sites have been used as structural and functional probes in seven transmembrane receptors (7TM), but as yet all the engineered sites have…”
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One-step purification and characterization of human pancreatic lipase expressed in insect cells by Thirstrup, Kenneth, Carrière, Frédéric, Hjorth, Siv, Rasmussen, Poul B., Wöldike, Helle, Nielsen, Per F., Thim, Lars

“…A cDNA clone encoding the sequence of human pancreatic lipase (HPL) was subcloned into the baculovirus transfer vector pVL1392 and used in co-transfection of…”
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Structure-function relationships in naturally occurring mutants of pancreatic lipase by Carrière, F, Thirstrup, K, Boel, E, Verger, R, Thim, L

“…From primary structure comparison, the pancreatic lipase family is now divided into three subgroups: classical pancreatic lipases, pancreatic lipase-related…”
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Metal-Ion Sites as Structural and Functional Probes of Helix-Helix Interactions in 7TM Receptors by ELLING, CHRISTIAN E., THIRSTRUP, KENNETH, NIELSEN, SØREN M., HJORTH, SIV A., SCHWARTZ, THUE W.

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Engineering of metal-ion sites as distance constraints in structural and functional analysis of 7TM receptors by Elling, Christian E, Thirstrup, Kenneth, Nielsen, Søren M, Hjorth, Siv A, Schwartz, Thue W

“…G-protein-coupled receptors with their seven transmembrane (7TM) segments constitute the largest superfamily of proteins known. Unfortunately, still only…”
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Cloning and Expression in Insect Cells of two Pancreatic Lipases and a Procolipase from Myocastor coypus by Thirstrup, Kenneth, Carrière, Frédéric, Hjorth, Siv A., Rasmussen, Poul B., Nielsen, Per F., Ladefoged, Claus, Thim, Lars, Boel, Esper

“…The physiological role of pancreatic lipases has traditionally been assigned solely to triacylglyceride metabolism, while the digestion of phospholipids…”
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