Search Results - "Thimme, R"

Treatment with proton pump inhibitors increases the risk of secondary infections and ARDS in hospitalized patients with COVID‐19: coincidence or underestimated risk factor? by Luxenburger, H., Sturm, L., Biever, P., Rieg, S., Duerschmied, D., Schultheiss, M., Neumann‐Haefelin, C., Thimme, R., Bettinger, D.

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High-dimensional profiling reveals Tc17 cell enrichment in active Crohn’s disease and identifies a potentially targetable signature by Globig, A.-M., Hipp, A. V., Otto-Mora, P., Heeg, M., Mayer, L. S., Ehl, S., Schwacha, H., Bewtra, M., Tomov, V., Thimme, R., Hasselblatt, P., Bengsch, B.

“…The immune-pathology in Crohn’s disease is linked to dysregulated CD4+ T cell responses biased towards pathogenic TH17 cells. However, the role of CD8+ T cells…”
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Procedural and shunt‐related complications and mortality of the transjugular intrahepatic portosystemic shunt (TIPSS) by Bettinger, D., Schultheiss, M., Boettler, T., Muljono, M., Thimme, R., Rössle, M.

“…Summary Background The implantation of a transjugular intrahepatic portosystemic shunt (TIPSS) is a complex angiographic procedure performed in patients with…”
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The transcription factor c-JUN/AP-1 promotes HBV-related liver tumorigenesis in mice by Trierweiler, C, Hockenjos, B, Zatloukal, K, Thimme, R, Blum, H E, Wagner, E F, Hasselblatt, P

“…Hepatocellular carcinoma (HCC) develops as a consequence of chronic inflammatory liver diseases such as chronic hepatitis B virus (HBV) infection. The…”
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The albumin–bilirubin grade improves hepatic reserve estimation post‐sorafenib failure: implications for drug development by Pinato, D. J., Yen, C., Bettinger, D., Ramaswami, R., Arizumi, T., Ward, C., Pirisi, M., Burlone, M. E., Thimme, R., Kudo, M., Sharma, R.

“…Summary Background Drug development in hepatocellular carcinoma (HCC) is limited by disease heterogeneity, with hepatic reserve being a major source of…”
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Treatment with proton pump inhibitors is associated with increased mortality in patients with pyogenic liver abscess by Bettinger, D., Martin, D., Rieg, S., Schultheiss, M., Buettner, N., Thimme, R., Boettler, T.

“…Summary Background Proton pump inhibitors (PPI) are often used in patients with gastro‐esophageal reflux and peptic ulcer disease. A higher risk for infectious…”
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The German Network for Personalized Medicine to enhance patient care and translational research by Illert, A. L., Stenzinger, A., Bitzer, M., Horak, P., Gaidzik, V. I., Möller, Y., Beha, J., Öner, Ö., Schmitt, F., Laßmann, S., Ossowski, S., Schaaf, C. P., Hallek, M., Brümmendorf, T. H., Albers, P., Fehm, T., Brossart, P., Glimm, H., Schadendorf, D., Bleckmann, A., Brandts, C. H., Esposito, I., Mack, E., Peters, C., Bokemeyer, C., Fröhling, S., Kindler, T., Algül, H., Heinemann, V., Döhner, H., Bargou, R., Ellenrieder, V., Hillemanns, P., Lordick, F., Hochhaus, A., Beckmann, M. W., Pukrop, T., Trepel, M., Sundmacher, L., Wesselmann, S., Nettekoven, G., Kohlhuber, F., Heinze, O., Budczies, J., Werner, M., Nikolaou, K., Beer, A. J., Tabatabai, G., Weichert, W., Keilholz, U., Boerries, M., Kohlbacher, O., Duyster, J., Thimme, R., Seufferlein, T., Schirmacher, P., Malek, N. P.

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Transfusion-transmitted hepatitis E in Germany, 2013 by Huzly, D, Umhau, M, Bettinger, D, Cathomen, T, Emmerich, F, Hasselblatt, P, Hengel, H, Herzog, R, Kappert, O, Maassen, S, Schorb, E, Schulz-Huotari, C, Thimme, R, Unmüssig, R, Wenzel, J J, Panning, M

“…The reported IgG seroprevalence against hepatitis E virus (HEV) in German blood donations is 6.8%, and HEV RNA detected in 0.08%, but documented evidence for…”
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Editorial: is proton pump inhibitor use associated with worse outcomes in patients with liver abscesses? Authors’ reply by Bettinger, D., Thimme, R., Boettler, T.

“…Linked Content This article is linked to Bettinger et al and Tabibian and Lindor papers. To view these articles visit https://doi.org/10.1111/apt.14512 and…”
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On‐target sorafenib toxicity predicts improved survival in hepatocellular carcinoma: a multi‐centre, prospective study by Howell, J., Pinato, D. J., Ramaswami, R., Bettinger, D., Arizumi, T., Ferrari, C., Yen, C., Gibbin, A., Burlone, M. E., Guaschino, G., Sellers, L., Black, J., Pirisi, M., Kudo, M., Thimme, R., Park, J.‐W., Sharma, R.

“…Summary Background Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide and has high mortality despite treatment. While sorafenib has a…”
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Responsiveness of HBV-specific CD8+ T cells to PD1 pathway blockade is linked to TCF1 expression by Schuch, A, Wieland, D, Hofmann, M, Thimme, R

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Perspectives of immunotherapy in hepatocellular carcinoma (HCC) by Büttner, N, Schmidt, N, Thimme, R

“…Immunotherapy is considered a new treatment option for many tumor entities, as decades of research into cancer immunotherapy have recently yielded promising…”
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Efficacy and safety of transjugular intrahepatic portosystemic shunt (TIPSS) in 40 patients with hepatocellular carcinoma by Bettinger, D., Knüppel, E., Euringer, W., Spangenberg, H. C., Rössle, M., Thimme, R., Schultheiß, M.

“…Summary Background Portal hypertension and hepatocellular carcinoma (HCC) are major complications of advanced liver cirrhosis. Thus, patients are often…”
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Differential Contribution of Progenitor and Terminal Subsets of Exhausted CD8+ T Cells in Chronic HBV versus HCV Infection by Schuch, A, Wieland, D, Hofmann, M, Thimme, R

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Characterization and Functional Modulation of HBV-Specific CD4+ T Cell Responses by Jacobi, F.J, Flecken, T, Thimme, R, Boettler, T

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VΔ1 T Cells Differentiate into Cytotoxic Effector Cells in Chronic Viral Hepatitis by Binder, B, Hoh, A, Thimme, R, Hofmann, M

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Chronic HBV Infection Drives Expansion of Adaptive NK Cells by Müller, P.A, Schuch, A, Thimme, R, Hofmann, M

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COVID-19 associated pneumonia despite repeatedly negative PCR-analysis from oropharyngeal swabs by Hornuss, D, Laubner, K, Monasterio, C, Thimme, R, Wagner, D

“…A 46-year old construction worker presented at the emergency department with two orthostatic syncopes. The patient complained of prolonged fever and coughs for…”
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P0392 : Transarterial chemoembolisation in patients with metastatic hepatocellular carcinoma by Bettinger, D, Spode, R, Thimme, R, Schultheiß, M

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Serum markers of hepatocellular carcinoma by Spangenberg, H C, Thimme, R, Blum, H E

“…Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in some areas of the world with increasing incidence worldwide. Most of patients with…”
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