Search Results - "Thilakasiri, Pathum S."

Combination of bazedoxifene with chemotherapy and SMAC-mimetics for the treatment of colorectal cancer by Dmello, Rhynelle S., Palmieri, Michelle, Thilakasiri, Pathum S., Doughty, Larissa, Nero, Tracy L., Poh, Ashleigh R., To, Sarah Q., Lee, Erinna F., Douglas Fairlie, W., Mielke, Lisa, Parker, Michael W., Poon, Ivan K. H., Batlle, Eduard, Ernst, Matthias, Chand, Ashwini L.

“…Excessive STAT3 signalling via gp130, the shared receptor subunit for IL-6 and IL-11, contributes to disease progression and poor survival outcomes in patients…”
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Repurposing of drugs as STAT3 inhibitors for cancer therapy by Thilakasiri, Pathum S., Dmello, Rhynelle S., Nero, Tracy L., Parker, Michael W., Ernst, Matthias, Chand, Ashwini L.

“…Drug repurposing is a valuable approach in delivering new cancer therapeutics rapidly into the clinic. Existing safety and patient tolerability data for drugs…”
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