Search Results - "Thijssen, Vito"
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Detection of Antibodies in Blood Plasma Using Bioluminescent Sensor Proteins and a Smartphone
Published in Analytical chemistry (Washington) (19-04-2016)“…Antibody detection is of fundamental importance in many diagnostic and bioanalytical assays, yet current detection techniques tend to be laborious and/or…”
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A study on the effect of synthetic α-to-β 3 -amino acid mutations on the binding of phosphopeptides to 14-3-3 proteins
Published in Chemical communications (Cambridge, England) (05-12-2019)“…Here we describe the synthesis of a series of α,β-phosphopeptides, based on the phosphoepitope site on YAP1 (yes-associated protein 1), and the biochemical,…”
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Suppression of Formylation Provides an Alternative Approach to Vacant Codon Creation in Bacterial In Vitro Translation
Published in Angewandte Chemie International Edition (01-12-2020)“…Genetic code reprogramming is a powerful approach to controlled protein modification. A remaining challenge, however, is the generation of vacant codons. We…”
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A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein
Published in Proceedings of the National Academy of Sciences - PNAS (27-06-2023)“…The ongoing COVID-19 pandemic has had great societal and health consequences. Despite the availability of vaccines, infection rates remain high due to immune…”
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The assessment of Pseudomonas aeruginosa lectin LecA binding characteristics of divalent galactosides using multiple techniques
Published in Glycobiology (Oxford) (18-12-2021)“…Abstract Pseudomonas aeruginosa is a widespread opportunistic pathogen that is capable of colonizing various human tissues and is resistant to many…”
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Macrocyclic peptides as allosteric inhibitors of nicotinamide N -methyltransferase (NNMT)
Published in RSC chemical biology (07-10-2021)“…Nicotinamide N -methyltransferase (NNMT) methylates nicotinamide to form 1-methylnicotinamide (MNA) using S -adenosyl- l -methionine (SAM) as the methyl donor…”
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Inhibition of H1 and H5 Influenza A Virus Entry by Diverse Macrocyclic Peptides Targeting the Hemagglutinin Stem Region
Published in ACS chemical biology (16-09-2022)“…Influenza A viruses pose a serious pandemic risk, while generation of efficient vaccines against seasonal variants remains challenging. There is thus a…”
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Suppression of Formylation Provides an Alternative Approach to Vacant Codon Creation in Bacterial In Vitro Translation
Published in Angewandte Chemie (01-12-2020)“…Genetic code reprogramming is a powerful approach to controlled protein modification. A remaining challenge, however, is the generation of vacant codons. We…”
Get full text
Journal Article -
9
Macrocyclic peptides as allosteric inhibitors of nicotinamide -methyltransferase (NNMT)
Published in RSC chemical biology (07-10-2021)“…Nicotinamide N -methyltransferase (NNMT) methylates nicotinamide to form 1-methylnicotinamide (MNA) using S -adenosyl- l -methionine (SAM) as the methyl donor…”
Get full text
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