Search Results - "Thijssen, Henk H.W"

The potent antioxidant activity of the vitamin K cycle in microsomal lipid peroxidation by Vervoort, Lily M.T, Ronden, Jacintha E, Thijssen, Henk H.W

“…In the vitamin K cycle, vitamin K-hydroquinone, the active cofactor for -γ-glutamylcarboxylase, is continuously regenerated. The successive pathways contain…”
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Matrix Gla Protein Accumulates at the Border of Regions of Calcification and Normal Tissue in the Media of the Arterial Vessel Wall by Spronk, Henri M.H., Soute, Berry A.M., Schurgers, Leon J., Cleutjens, Jack P.M., Thijssen, Henk H.W., De Mey, Jo G.R., Vermeer, Cees

“…Vitamin K-dependent matrix Gla protein (MGP) has been suggested to play a role in the inhibition of soft-tissue calcification. Here we report the expression of…”
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Tissue distribution of K-vitamers under different nutritional regimens in the rat by Ronden, Jacintha E, Thijssen, Henk H.W, Vermeer, Cees

“…Two forms of vitamin K [phylloquinone (K 1) and menaquinone-4 (MK-4)] were added to vitamin K-deficient rat food in varying amounts. These diets were given as…”
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Intestinal flora is not an intermediate in the phylloquinone-menaquinone-4 conversion in the rat by Ronden, Jacintha E, Drittij-Reijnders, Marie-José, Vermeer, Cees, Thijssen, Henk H.W

“…To elucidate the role of intestinal bacteria in the conversion of phylloquinone into menaquinone-4 (MK-4) we investigated the tissue distribution of vitamin K…”
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Effects of 2,3,7,8-tetrachlorodibenzo- p-dioxin or 2,2′,4,4′,5,5′-hexachloro-biphenyl on vitamin K-dependent blood coagulation in male and female WAG/rij-rats by Bouwman, Carolien A., Van Dam, Edith, Fase, Kitty M., Koppe, Janna G., Seinen, Willem, Thijssen, Henk H.W., Vermeer, Cees, Van den Berg, Martin

“…Newborns are susceptible to hemorrhages (hemorrhagic disease of the newborn or HDN) due to vitamin K deficiency. Induction of cytochrome P450 in the fetal…”
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Menadione is a metabolite of oral vitamin K by Thijssen, Henk H. W., Vervoort, Lily M. T., Schurgers, Leon J., Shearer, Martin J.

“…Phylloquinone is converted into menaquinone-4 and accumulates in extrahepatic tissues. Neither the route nor the function of the conversion is known. One…”
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The relative effects of phylloquinone and menaquinone-4 on the blood coagulation factor synthesis in vitamin K-deficient rats by Groenen-van Dooren, M M, Soute, B A, Jie, K S, Thijssen, H H, Vermeer, C

“…Rats were made vitamin K-deficient by feeding them a 1:1 (w/w) mixture of a commercial vitamin K-depleted diet and boiled white rice. After one week of…”
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Acenocoumarol Pharmacokinetics in Relation to Cytochrome P450 2C9 Genotype by Thijssen, Henk H. W., Ritzen, Bas

“…Background and objectives Cytochrome P450 (CYP) 2C9 is one of the major CYP enzymes involved in the biotransformation of drugs, among others, the oral…”
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Paracetamol (acetaminophen) warfarin interaction: NAPQI, the toxic metabolite of paracetamol, is an inhibitor of enzymes in the vitamin K cycle by Thijssen, Henk H, Soute, Berry A, Vervoort, Lily M, Claessens, Jolanda G

“…Paracetamol (acetaminophen) is generally considered to be the analgesic of choice for patients undergoing oral anticoagulant therapy. Occasionally, however,…”
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Pharmacogenetics of Acenocoumarol Pharmacodynamics by Morin, Sandrine, Bodin, Laurent, Loriot, Marie‐Anne, Thijssen, Henk H. W., Robert, Annie, Strabach, Soraya, Verstuyft, Céline, Tregouet, David‐Alexandre, Dubert, Liliane, Laurent‐Puig, Pierre, Funck‐Brentano, Christian, Jaillon, Patrice, Beaune, Philippe H., Becquemont, Laurent

“…Objective The aim of this study was to investigate the respective contribution of the different cytochrome P450 (CYP) 2C9 genetic polymorphisms to the…”
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Effects of complete renal denervation and selective afferent renal denervation on the hypertension induced by intrarenal norepinephrine infusion in conscious rats by Janssen, B J, van Essen, H, Vervoort-Peters, L H, Thijssen, H H, Derkx, F H, Struyker-Boudier, H A, Smits, J F

“…To test the hypothesis that continuous intrarenal norepinephrine (NE) infusions produce hypertension via activation of afferent renal nerves (ARN), rats were…”
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Altered pharmacokinetics of R‐ and S‐acenocoumarol in a subject heterozygous for CYP2C93 by Thijssen, Henk H.W., Drittij, Marie‐José, Vervoort, Lily M.T., Vries‐Hanje, Johanna C.

“…Objective Our objective was to study the pharmacokinetics of R‐ and S‐acenocoumarol in a subject who was highly sensitive to the anticoagulant effect of…”
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Intestinal, hepatic, and circulating vitamin K levels at low and high intakes of vitamin K in rats by Koivu-Tikkanen, Terhi J., Schurgers, Leon J., Thijssen, Henk H. W., Vermeer, Cees

“…The aim of the present study was to assess how high doses of dietary vitamin K influence the intestinal profile of K-vitamins in vitamin K-deficient rats, and…”
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Dermal uptake of polycyclic aromatic hydrocarbons after hairwash with coal-tar shampoo by van Schooten, F J, Moonen, E J, Rhijnsburger, E, van Agen, B, Thijssen, H H, Kleinjans, J C

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Effects of 2,3,7,8-tetrachlorodibenzo-P-dioxin or 2,2', 4,4', 5,5'-hexachlorobiphenyl on vitamin K-dependent blood coagulation in male and female WAG/RIJ-rats by BOUWMAN, C. A, VAN DAM, E, FASE, K. M, KOPPE, J. G, SEINEN, W, THIJSSEN, H. H. W, VERMEER, C, VAN DEN BERG, M

“…Newborns are susceptible to hemorrhages (hemorrhagic disease of the newborn or HDN) due to vitamin K deficiency. Induction of cytochrome P450 in the fetal…”
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Comparison of 11β-hydroxysteroid dehydrogenase in spontaneously hypertensive and Wistar-Kyoto rats by Hermans, J.J.Rob, Steckel, Birgit, Thijssen, Henk H.W., Janssen, Ben J.A., Netter, Karl J., Maser, Edmund

“…11β-Hydroxysteroid dehydrogenase (11β-HSD) modulates glucocorticoid interactions with mineralocorticoid and glucocorticoid receptors in vivo, by converting…”
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The interaction of the prostaglandin E derivative rioprostil with oral anticoagulant agents by Thijssen, H H, Hamulyàk, K

“…The prostaglandin E1 analogue rioprostil was tested for potential interaction with oral anticoagulant therapy in healthy male volunteers. The effect of…”
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Natural prenylquinones inhibit the enzymes of the vitamin K cycle in vitro by Ronden, Jacintha E., Soute, Berry A.M., Thijssen, Henk H.W., Saupe, Jörg, Vermeer, Cees

“…Vitamin K belongs to a class of compounds commonly known as prenylquinones. Three other prenylquinones which are abundantly found in food are plastoquinone-9,…”
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Vitamin K reductases in normal and in warfarin-resistant rats by Vermeer, C, Soute, B A, Aalten, M, Knapen, M H, Thijssen, H H

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The placental transport of [3H]vitamin K1 in rats by Hamulyák, K, de Boer-van den Berg, M A, Thijssen, H H, Hemker, H C, Vermeer, C

“…In this paper we describe the placental transport of [3H]vitamin K1 in pregnant rats during the first 24 h after the oral administration of the vitamin…”
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