Search Results - "Thijssen, E"

Obesity and osteoarthritis, more than just wear and tear: pivotal roles for inflamed adipose tissue and dyslipidaemia in obesity-induced osteoarthritis by Thijssen, Eva, van Caam, Arjan, van der Kraan, Peter M

“…OA is a degenerative joint disease characterized by articular cartilage degradation, osteophyte formation, synovitis, and subchondral bone sclerosis. One of…”
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DNA methylation signatures link prenatal famine exposure to growth and metabolism by Tobi, Elmar W., Goeman, Jelle J., Monajemi, Ramin, Gu, Hongcang, Putter, Hein, Zhang, Yanju, Slieker, Roderick C., Stok, Arthur P., Thijssen, Peter E., Müller, Fabian, van Zwet, Erik W., Bock, Christoph, Meissner, Alexander, Lumey, L. H., Eline Slagboom, P., Heijmans, Bastiaan T.

“…Periconceptional diet may persistently influence DNA methylation levels with phenotypic consequences. However, a comprehensive assessment of the…”
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MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4 by Huijbers, Maartje G., Zhang, Wei, Klooster, Rinse, Niks, Erik H., Friese, Matthew B., Straasheijm, Kirsten R., Thijssen, Peter E., Vrolijk, Hans, Plomp, Jaap J., Vogels, Pauline, Losen, Mario, Van der Maarel, Silvère M., Burden, Steven J., Verschuuren, Jan J.

“…Myasthenia gravis (MG) is a severely debilitating autoimmune disease that is due to a decrease in the efficiency of synaptic transmission at neuromuscular…”
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Mutations in CDCA7 and HELLS cause immunodeficiency–centromeric instability–facial anomalies syndrome by Thijssen, Peter E., Ito, Yuya, Grillo, Giacomo, Wang, Jun, Velasco, Guillaume, Nitta, Hirohisa, Unoki, Motoko, Yoshihara, Minako, Suyama, Mikita, Sun, Yu, Lemmers, Richard J. L. F., de Greef, Jessica C., Gennery, Andrew, Picco, Paolo, Kloeckener-Gruissem, Barbara, Güngör, Tayfun, Reisli, Ismail, Picard, Capucine, Kebaili, Kamila, Roquelaure, Bertrand, Iwai, Tsuyako, Kondo, Ikuko, Kubota, Takeo, van Ostaijen-Ten Dam, Monique M., van Tol, Maarten J. D., Weemaes, Corry, Francastel, Claire, van der Maarel, Silvère M., Sasaki, Hiroyuki

“…The life-threatening Immunodeficiency, Centromeric Instability and Facial Anomalies (ICF) syndrome is a genetically heterogeneous autosomal recessive disorder…”
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Intrinsic epigenetic regulation of the D4Z4 macrosatellite repeat in a transgenic mouse model for FSHD by Krom, Yvonne D, Thijssen, Peter E, Young, Janet M, den Hamer, Bianca, Balog, Judit, Yao, Zizhen, Maves, Lisa, Snider, Lauren, Knopp, Paul, Zammit, Peter S, Rijkers, Tonnie, van Engelen, Baziel G M, Padberg, George W, Frants, Rune R, Tawil, Rabi, Tapscott, Stephen J, van der Maarel, Silvère M

“…Facioscapulohumeral dystrophy (FSHD) is a progressive muscular dystrophy caused by decreased epigenetic repression of the D4Z4 macrosatellite repeats and…”
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SOX Antibodies in Small-Cell Lung Cancer and Lambert-Eaton Myasthenic Syndrome: Frequency and Relation With Survival by TITULAER, Maarten J, KLOOSTER, Rinse, VAN DER MAAREL, Silvère M, VERSCHUUREN, Jan J. G. M, POTMAN, Marko, SABATER, Lidia, GRAUS, Francesc, HEGEMAN, Ingrid M, THIJSSEN, Peter E, WIRTZ, Paul W, TWIJNSTRA, Albert, SILLEVIS SMITT, Peter A. E

“…SOX1 antibodies are common in small-cell lung carcinoma (SCLC) with and without paraneoplastic syndrome (PNS) and can serve as serological tumor marker…”
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TGF-β is a potent inducer of Nerve Growth Factor in articular cartilage via the ALK5-Smad2/3 pathway. Potential role in OA related pain? by Blaney Davidson, E.N, van Caam, A.P.M, Vitters, E.L, Bennink, M.B, Thijssen, E, van den Berg, W.B, Koenders, M.I, van Lent, P.L.E.M, van de Loo, F.A.J, van der Kraan, P.M

“…Summary Objective Pain is the main problem for patients with osteoarthritis (OA). Pain is linked to inflammation, but in OA a subset of patients suffers from…”
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Electrophysiological Responses in the Human S3 Nerve During Sacral Neuromodulation for Fecal Incontinence by Gmel, Gerrit E., Vollebregt, Paul F., Thijssen, Marjolein E. G., Santos Escapa, Rosana, McAlees, Eleanor, Mugan, Dave, Parker, John L., Knowles, Charles H.

“…Intra-operative electrode placement for sacral neuromodulation (SNM) relies on visual observation of motor contractions alone, lacking complete information on…”
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Expression of TGFβ-family signalling components in ageing cartilage: Age-related loss of TGFβ and BMP receptors by van Caam, Arjan, Madej, Wojciech, Thijsen, Eva, Garcia de Vinuesa, Amaya, van den Berg, Wim, Goumans, Marie-José, ten Dijke, Peter, Blaney Davidson, Esmeralda, van der Kraan, Peter, Ph.D

“…Summary Objective Ageing is the main risk factor for osteoarthritis (OA).We investigated if expression of transforming growth factor β (TGFβ)-family…”
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Physical damage to healthy articular cartilage induces expression of the pain mediator NGF by a TGFβ-mediated process. Potential role in OA-related pain? by Blaney Davidson, E.N, Thijssen, E, van der Kraan, P.M

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Loss of ZBTB24 impairs nonhomologous end-joining and class-switch recombination in patients with ICF syndrome by Helfricht, Angela, Thijssen, Peter E, Rother, Magdalena B, Shah, Rashmi G, Du, Likun, Takada, Sanami, Rogier, Mélanie, Moritz, Jacques, IJspeert, Hanna, Stoepker, Chantal, van Ostaijen-Ten Dam, Monique M, Heyer, Vincent, Luijsterburg, Martijn S, de Groot, Anton, Jak, Rianca, Grootaers, Gwendolynn, Wang, Jun, Rao, Pooja, Vertegaal, Alfred C O, van Tol, Maarten J D, Pan-Hammarström, Qiang, Reina-San-Martin, Bernardo, Shah, Girish M, van der Burg, Mirjam, van der Maarel, Silvère M, van Attikum, Haico

“…The autosomal recessive immunodeficiency, centromeric instability, and facial anomalies (ICF) syndrome is a genetically heterogeneous disorder. Despite the…”
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Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways by Deelen, Joris, Uh, Hae-Won, Monajemi, Ramin, van Heemst, Diana, Thijssen, Peter E., Böhringer, Stefan, van den Akker, Erik B., de Craen, Anton J. M., Rivadeneira, Fernando, Uitterlinden, André G., Westendorp, Rudi G. J., Goeman, Jelle J., Slagboom, P. Eline, Houwing-Duistermaat, Jeanine J., Beekman, Marian

“…In genome-wide association studies (GWAS) of complex traits, single SNP analysis is still the most applied approach. However, the identified SNPs have small…”
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Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers by DEELEN, Joris, BEEKMAN, Marian, UITTERLINDEN, André G, HOFMAN, Albert, DE CRAEN, Anton J. M, METSPALU, Andres, PEDERSEN, Nancy L, VAN DUIJN, Cornelia M, WOUTER JUKEMA, J, HOUWING-DUISTERMAAT, Jeanine J, SAMANI, Nilesh J, SLAGBOOM, P. Eline, CODD, Veryan, TROMPET, Stella, BROER, Linda, HÄGG, Sara, FISCHER, Krista, THIJSSEN, Peter E, SUCHIMAN, H. Eka D, POSTMUS, Iris

“…Human leukocyte telomere length (LTL) decreases with age and shorter LTL has previously been associated with increased prospective mortality. However, it is…”
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Circulating biomarkers associated with aortic diameter in male and female patients with thoracic aortic disease: a cross-sectional study by Meccanici, Frederike, Thijssen, Carlijn G E, Dekker, Silvy, Bons, Lidia R, Gökalp, Arjen L, de Rijke, Yolanda B, Takkenberg, Johanna J M, Mokhles, Mostafa M, Bekkers, Jos A, Boersma, Eric, Bouwens, Elke, van der Bosch, Annemien E, van Kimmenade, Roland R L, Roos-Hesselink, Jolien W

“…As thoracic aortic disease (TAD) is generally asymptomatic, biomarkers are needed to provide insight into early progression. We aimed to examine the…”
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Correlation analysis of clinical parameters with epigenetic modifications in the DUX4 promoter in FSHD by Balog, Judit, Thijssen, Peter E., de Greef, Jessica C., Shah, Bharati, van Engelen, Baziel G.M., Yokomori, Kyoko, Tapscott, Stephen J., Tawil, Rabi, van der Maarel, Silvère M.

“…The aim of our study was to identify relationships between epigenetic parameters correlating with a relaxed chromatin state of the DUX4 promoter region and…”
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The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80 by Typas, Dimitris, Luijsterburg, Martijn S., Wiegant, Wouter W., Diakatou, Michaela, Helfricht, Angela, Thijssen, Peter E., van de Broek, Bram, Mullenders, Leon H., van Attikum, Haico

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Expanding the mutation spectrum in ICF syndrome: Evidence for a gender bias in ICF2 by van den Boogaard, M.L., Thijssen, P.E., Aytekin, C., Licciardi, F., Kıykım, A.A., Spossito, L., Dalm, V.A.S.H., Driessen, G.J., Kersseboom, R., de Vries, F., van Ostaijen‐ten Dam, M.M., Ikinciogullari, A., Dogu, F., Oleastro, M., Bailardo, E., Daxinger, L., Nain, E., Baris, S., van Tol, M.J.D., Weemaes, C., van der Maarel, S.M.

“…Background Immunodeficiency, centromeric instability, and facial anomalies (ICF) syndrome is a rare, genetically heterogeneous, autosomal recessive disorder…”
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Age-related loss of the transforming growth factor β receptor ALK5 precedes osteoarthritis development in cartilage by van Caam, A, Blaney Davidson, E, Thijssen, E, van den Berg, W, van der Kraan, P

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TGF-β is a potent inducer of nerve growth factor in articular cartilage via the ALK5-Smad2/3 pathway. potential role in OA related pain? by Davidson, E.N. Blaney, van Caam, A.P, Vitters, E.L, Bennink, M.B, Thijssen, E, van den Berg, W.B, Koenders, M.I, van Lent, P.L, van de Loo, F.A, van der Kraan, P.M

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Biodesulphurized subbituminous coal by different fungi and bacteria studied by reductive pyrolysis. Part 1: Initial coal by Gonsalvesh, L., Marinov, S.P., Stefanova, M., Yürüm, Y., Dumanli, A.G., Dinler-Doganay, G., Kolankaya, N., Sam, M., Carleer, R., Reggers, G., Thijssen, E., Yperman, J.

“…One of the perspective methods for clean solid fuels production is biodesulphurization. In order to increase the effect of this approach it is necessary to…”
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