Search Results - "Thienel, Constanze"

β Cell-Specific Deletion of the IL-1 Receptor Antagonist Impairs β Cell Proliferation and Insulin Secretion by Böni-Schnetzler, Marianne, Häuselmann, Stéphanie P., Dalmas, Elise, Meier, Daniel T., Thienel, Constanze, Traub, Shuyang, Schulze, Friederike, Steiger, Laura, Dror, Erez, Martin, Praxedis, Herrera, Pedro L., Gabay, Cem, Donath, Marc Y.

“…Interleukin-1 receptor antagonist (IL-1Ra) is elevated in the circulation during obesity and type 2 diabetes (T2D) but is decreased in islets from patients…”
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Inhibition of IL-1beta improves Glycaemia in a Mouse Model for Gestational Diabetes by Schulze, Friederike, Wehner, Josua, Kratschmar, Denise V., Makshana, Valmir, Meier, Daniel T., Häuselmann, Stéphanie P., Dalmas, Elise, Thienel, Constanze, Dror, Erez, Wiedemann, Sophia J., Traub, Shuyang, Nordmann, Thierry M., Rachid, Leila, De Baat, Axel, Rohm, Theresa V., Zhao, Cheng, Odermatt, Alex, Böni-Schnetzler, Marianne, Donath, Marc Y.

“…Gestational diabetes mellitus (GDM) is one of the most common diseases associated with pregnancy, however, the underlying mechanisms remain unclear. Based on…”
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Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation by Dror, Erez, Dalmas, Elise, Meier, Daniel T, Wueest, Stephan, Thévenet, Julien, Thienel, Constanze, Timper, Katharina, Nordmann, Thierry M, Traub, Shuyang, Schulze, Friederike, Item, Flurin, Vallois, David, Pattou, Francois, Kerr-Conte, Julie, Lavallard, Vanessa, Berney, Thierry, Thorens, Bernard, Konrad, Daniel, Böni-Schnetzler, Marianne, Donath, Marc Y

“…The cytokine IL-1β has well-established harmful effects on pancreatic islet function. Donath and colleagues identify an acute wave of postprandial IL-1β…”
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Glucose-Dependent Insulinotropic Peptide Stimulates Glucagon-Like Peptide 1 Production by Pancreatic Islets via Interleukin 6, Produced by α Cells by Timper, Katharina, Dalmas, Elise, Dror, Erez, Rütti, Sabine, Thienel, Constanze, Sauter, Nadine S, Bouzakri, Karim, Bédat, Benoit, Pattou, Francois, Kerr-Conte, Julie, Böni-Schnetzler, Marianne, Donath, Marc Y

“…Background & Aims Glucose-dependent insulinotropic peptide (GIP) induces production of interleukin 6 (IL6) by adipocytes. IL6 increases production of…”
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Angiotensin II induces interleukin-1β-mediated islet inflammation and β-cell dysfunction independently of vasoconstrictive effects by Sauter, Nadine S, Thienel, Constanze, Plutino, Yuliya, Kampe, Kapil, Dror, Erez, Traub, Shuyang, Timper, Katharina, Bédat, Benoit, Pattou, Francois, Kerr-Conte, Julie, Jehle, Andreas W, Böni-Schnetzler, Marianne, Donath, Marc Y

“…Pathological activation of the renin-angiotensin system (RAS) is associated with the metabolic syndrome, and the new onset of type 2 diabetes can be delayed by…”
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Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production by Dalmas, Elise, Lehmann, Frank M., Dror, Erez, Wueest, Stephan, Thienel, Constanze, Borsigova, Marcela, Stawiski, Marc, Traunecker, Emmanuel, Lucchini, Fabrizio C., Dapito, Dianne H., Kallert, Sandra M., Guigas, Bruno, Pattou, Francois, Kerr-Conte, Julie, Maechler, Pierre, Girard, Jean-Philippe, Konrad, Daniel, Wolfrum, Christian, Böni-Schnetzler, Marianne, Finke, Daniela, Donath, Marc Y.

“…Pancreatic-islet inflammation contributes to the failure of β cell insulin secretion during obesity and type 2 diabetes. However, little is known about the…”
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Postprandial macrophage-derived IL-1[beta] stimulates insulin, and both synergistically promote glucose disposal and inflammation by Dror, Erez, Dalmas, Elise, Meier, Daniel T, Wueest, Stephan, Thévenet, Julien, Thienel, Constanze, Timper, Katharina, Nordmann, Thierry M, Traub, Shuyang, Schulze, Friederike, Item, Flurin, Vallois, David, Pattou, Francois, Kerr-Conte, Julie, Lavallard, Vanessa, Berney, Thierry, Thorens, Bernard, Konrad, Daniel, Böni-Schnetzler, Marianne, Donath, Marc Y

“…The deleterious effect of chronic activation of the IL-1[beta] system on type 2 diabetes and other metabolic diseases is well documented. However, a possible…”
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Angiotensin II Induces Interleukin-1[Beta]-Mediated Islet Inflammation and [Beta]-Cell Dysfunction Independently of Vasoconstrictive Effects by Sauter, Nadine S, Thienel, Constanze, Plutino, Yuliya, Kampe, Kapil, Dror, Erez, Traub, Shuyang, Timper, Katharina, Bédat, Benoit, Pattou, Francois, Kerr-Conte, Julie, Jehle, Andreas W, Böni-Schnetzler, Marianne, Donath, Marc Y

“…Pathological activation of the renin-angiotensin system (RAS) is associated with the metabolic syndrome, and the new onset of type 2 diabetes can be delayed by…”
Get full text