Search Results - "Thiele, A"

Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome by Devinsky, Orrin, Cross, J. Helen, Laux, Linda, Marsh, Eric, Miller, Ian, Nabbout, Rima, Scheffer, Ingrid E, Thiele, Elizabeth A, Wright, Stephen

“…Among children and young adults with the Dravet syndrome, a developmental disorder that is associated with treatment-resistant seizures, cannabidiol reduced…”
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Circulating Tumor Cells: Fluid Surrogates of Solid Tumors by Thiele, J.-A, Bethel, K, Králí ková, M, Kuhn, P

“…Evaluation of circulating tumor cells (CTCs) has demonstrated clinical validity as a prognostic tool based on enumeration, but since the introduction of this…”
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Implementing f‑Block Metal Ions in Medicine: Tuning the Size Selectivity of Expanded Macrocycles by Thiele, Nikki A, Woods, Joshua J, Wilson, Justin J

“…The f-block elements, which comprise both the lanthanide and actinide series, possess interesting spectroscopic, magnetic, and nuclear properties that make…”
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The natural history of epilepsy in tuberous sclerosis complex by Chu‐Shore, Catherine J., Major, Philippe, Camposano, Susana, Muzykewicz, David, Thiele, Elizabeth A.

“…Summary Background:  Although epilepsy affects most patients with tuberous sclerosis complex (TSC), little is known about the natural history of epilepsy in…”
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The case for assessing cannabidiol in epilepsy by Cilio, Maria Roberta, Thiele, Elizabeth A., Devinsky, Orrin

“…Summary Intractable epilepsies have an extraordinary impact on cognitive and behavioral function and quality of life, and the treatment of seizures represents…”
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Comparison of spatial integration and surround suppression characteristics in spiking activity and the local field potential in macaque V1 by Gieselmann, M. A., Thiele, A.

“…Neurons in primary visual cortex exhibit well documented centre–surround receptive field organization, whereby the centre is dominated by excitatory influences…”
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Cannabidiol as a new treatment for drug‐resistant epilepsy in tuberous sclerosis complex by Hess, Evan J., Moody, Kirsten A., Geffrey, Alexandra L., Pollack, Sarah F., Skirvin, Lauren A., Bruno, Patricia L., Paolini, Jan L., Thiele, Elizabeth A.

“…Summary Objective Tuberous sclerosis complex (TSC) is an autosomal‐dominant genetic disorder with highly variable expression. The most common neurologic…”
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An Eighteen‐Membered Macrocyclic Ligand for Actinium‐225 Targeted Alpha Therapy by Thiele, Nikki A., Brown, Victoria, Kelly, James M., Amor‐Coarasa, Alejandro, Jermilova, Una, MacMillan, Samantha N., Nikolopoulou, Anastasia, Ponnala, Shashikanth, Ramogida, Caterina F., Robertson, Andrew K. H., Rodríguez‐Rodríguez, Cristina, Schaffer, Paul, Williams, Clarence, Babich, John W., Radchenko, Valery, Wilson, Justin J.

“…The 18‐membered macrocycle H2macropa was investigated for 225Ac chelation in targeted alpha therapy (TAT). Radiolabeling studies showed that macropa, at…”
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Structural-functional brain network coupling predicts human cognitive ability by Popp, Johanna L., Thiele, Jonas A., Faskowitz, Joshua, Seguin, Caio, Sporns, Olaf, Hilger, Kirsten

“…•Brain structure-function coupling captured by network communication models.•Stronger structure-function coupling is linked to higher general cognitive…”
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Mosaic and Intronic Mutations in TSC1/TSC2 Explain the Majority of TSC Patients with No Mutation Identified by Conventional Testing by Tyburczy, Magdalena E, Dies, Kira A, Glass, Jennifer, Camposano, Susana, Chekaluk, Yvonne, Thorner, Aaron R, Lin, Ling, Krueger, Darcy, Franz, David N, Thiele, Elizabeth A, Sahin, Mustafa, Kwiatkowski, David J

“…Tuberous sclerosis complex (TSC) is an autosomal dominant tumor suppressor gene syndrome due to germline mutations in either TSC1 or TSC2. 10-15% of TSC…”
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Acetylcholine contributes through muscarinic receptors to attentional modulation in V1 by Delicato, L. S, Gieselmann, M. A, Dayan, P, Herrero, J. L, Thiele, A, Roberts, M. J

“…Attention exerts a strong influence over neuronal processing in cortical areas. It selectively increases firing rates and affects tuning properties, including…”
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Tuning the Kinetic Inertness of Bi3+ Complexes: The Impact of Donor Atoms on Diaza-18-Crown‑6 Ligands as Chelators for 213Bi Targeted Alpha Therapy by Fiszbein, David J, Brown, Victoria, Thiele, Nikki A, Woods, Joshua J, Wharton, Luke, MacMillan, Samantha N, Radchenko, Valery, Ramogida, Caterina F, Wilson, Justin J

“…The radionuclide 213Bi can be applied for targeted α therapy (TAT): a type of nuclear medicine that harnesses α particles to eradicate cancer cells. To use…”
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Multicenter phase 2 trial of sirolimus for tuberous sclerosis: kidney angiomyolipomas and other tumors regress and VEGF- D levels decrease by Dabora, Sandra L, Franz, David Neal, Ashwal, Stephen, Sagalowsky, Arthur, DiMario, Jr, Francis J, Miles, Daniel, Cutler, Drew, Krueger, Darcy, Uppot, Raul N, Rabenou, Rahmin, Camposano, Susana, Paolini, Jan, Fennessy, Fiona, Lee, Nancy, Woodrum, Chelsey, Manola, Judith, Garber, Judy, Thiele, Elizabeth A

“…Tuberous sclerosis (TSC) related tumors are characterized by constitutively activated mTOR signaling due to mutations in TSC1 or TSC2. We completed a phase 2…”
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Understanding Self-Assembly and the Stabilization of Liquid/Liquid Interfaces: The Importance of Ligand Tail Branching and Oil-Phase Solvation by Premadasa, Uvinduni I., Ma, Ying-Zhong, Sacci, Robert L., Bocharova, Vera, Thiele, Nikki A., Doughty, Benjamin

“…[Display omitted] Organophosphorus-based ligands represent a versatile set of solvent extraction reagents whose chemical makeup plays an important role in…”
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Efficacy and safety of everolimus for subependymal giant cell astrocytomas associated with tuberous sclerosis complex (EXIST-1): a multicentre, randomised, placebo-controlled phase 3 trial by Franz, David Neal, Prof, Belousova, Elena, MD, Sparagana, Steven, MD, Bebin, E Martina, MD, Frost, Michael, MD, Kuperman, Rachel, MD, Witt, Olaf, MD, Kohrman, Michael H, MD, Flamini, J Robert, MD, Wu, Joyce Y, MD, Curatolo, Paolo, Prof, de Vries, Petrus J, Prof, Whittemore, Vicky H, PhD, Thiele, Elizabeth A, MD, Ford, James P, MS, Shah, Gaurav, MD, Cauwel, Helene, MSc, Lebwohl, David, MD, Sahmoud, Tarek, MD, Jozwiak, Sergiusz, MD

“…Summary Background Tuberous sclerosis complex is a genetic disorder leading to constitutive activation of mammalian target of rapamycin (mTOR) and growth of…”
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Tuberous sclerosis complex: diagnostic challenges, presenting symptoms, and commonly missed signs by Staley, Brigid A, Vail, Emily A, Thiele, Elizabeth A

“…To describe presenting symptoms and signs according to age group in a cohort of 243 patients with tuberous sclerosis complex (TSC) and identify earlier…”
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CNN BASED VEHICLE TRACK DETECTION IN COHERENT SAR IMAGERY: AN ANALYSIS OF DATA AUGMENTATION by Kuny, S., Hammer, H., Thiele, A.

“…The coherence image as a product of a coherent SAR image pair can expose even subtle changes in the surface of a scene, such as vehicle tracks. For machine…”
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Can we more precisely classify exposure to antenatal depression and anxiety in multivariable prediction models of pregnancy and birth outcomes: a population-based cohort study by Thiele, Grace A, Ryan, Deirdre M, Oberlander, Tim F, Hanley, Gillian E

“…Abstract Background Depression and anxiety are highly prevalent within the perinatal period and have been associated with myriad adverse pregnancy and birth…”
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Population genetic analysis of Chadian Guinea worms reveals that human and non-human hosts share common parasite populations by Thiele, Elizabeth A, Eberhard, Mark L, Cotton, James A, Durrant, Caroline, Berg, Jeffrey, Hamm, Kelsey, Ruiz-Tiben, Ernesto

“…Following almost 10 years of no reported cases, Guinea worm disease (GWD or dracunculiasis) reemerged in Chad in 2010 with peculiar epidemiological patterns…”
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3D MAPPING OF BURIED PIPES IN MULTI-CHANNEL GPR DATA by Karle, N., Boldt, M., Thiele, A., Thoennessen, U.

“…Ground Penetrating Radar (GPR) allows a non-destructive analysis of the subsurface by using electromagnetic waves. GPR is used in application fields such as…”
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