Search Results - "Thiebot, Bénédicte"
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Dynamics of Unfolded Protein Transport through an Aerolysin Pore
Published in Journal of the American Chemical Society (09-03-2011)“…Protein export is an essential mechanism in living cells and exported proteins are usually translocated through a protein-conducting channel in an unfolded…”
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Biomimetic Nanotubes Based on Cyclodextrins for Ion-Channel Applications
Published in Nano letters (11-11-2015)“…Biomimetic membrane channels offer a great potential for fundamental studies and applications. Here, we report the fabrication and characterization of short…”
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Elasticity, Adhesion, and Tether Extrusion on Breast Cancer Cells Provide a Signature of Their Invasive Potential
Published in ACS applied materials & interfaces (19-10-2016)“…We use single-cell force spectroscopy to compare elasticity, adhesion, and tether extrusion on four breast cancer cell lines with an increasing invasive…”
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Identification and Detection of a Peptide Biomarker and Its Enantiomer by Nanopore
Published in ACS central science (26-06-2024)“…Until now, no fast, low-cost, and direct technique exists to identify and detect protein/peptide enantiomers, because their mass and charge are identical. They…”
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Dynamics of a polyelectrolyte through aerolysin channel as a function of applied voltage and concentration
Published in The European physical journal. E, Soft matter and biological physics (11-05-2018)“… We describe the behaviour of a polyelectrolyte in confined geometry. The transport of a polyelectrolyte, dextran sulfate, through a recombinant protein…”
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Polyelectrolyte Entry and Transport through an Asymmetric α-Hemolysin Channel
Published in The journal of physical chemistry. B (27-11-2008)“…We study the entry and transport of a polyelectrolyte, dextran sulfate (DS), through an asymmetric α-hemolysin protein channel inserted into a planar lipid…”
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Polyelectrolyte and unfolded protein pore entrance depends on the pore geometry
Published in Biochimica et biophysica acta (01-06-2009)“…We determined the ability of Maltose Binding Protein and the polyelectrolyte dextran sulfate to enter into and interact with channels formed by Staphylococcus…”
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Mapping the Conformational Stability of Maltose Binding Protein at the Residue Scale Using Nuclear Magnetic Resonance Hydrogen Exchange Experiments
Published in Biochemistry (Easton) (06-11-2012)“…Being able to differentiate local fluctuations from global folding–unfolding dynamics of a protein is of major interest for improving our understanding of…”
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Urea denaturation of α-hemolysin pore inserted in planar lipid bilayer detected by single nanopore recording: Loss of structural asymmetry
Published in FEBS letters (24-07-2007)“…The aim of this work is to study pore protein denaturation inside a lipid bilayer and to probe current asymmetry as a function of the channel conformation. We…”
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Using Adhesive Micropatterns and AFM to Assess Cancer Cell Morphology and Mechanics
Published in ACS applied materials & interfaces (20-09-2023)“…The mechanical properties of living cells reflect their physiological and pathological state. In particular, cancer cells undergo cytoskeletal modifications…”
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Circulating Tumor Cells in Cancer Diagnostics and Prognostics by Single-Molecule and Single-Cell Characterization
Published in ACS sensors (24-02-2023)“…Circulating tumor cells (CTCs) represent an interesting source of biomarkers for diagnosis, prognosis, and the prediction of cancer recurrence, yet while they…”
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Validation of metaxin-2 deficient C. elegans as a model for MandibuloAcral Dysplasia associated to mtx-2 (MADaM) syndrome
Published in Communications biology (26-10-2024)“…MandibuloAcral Dysplasia associated to MTX2 gene (MADaM) is a recently described progeroid syndrome (accelerated aging disease) whose clinical manifestations…”
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Protein Gels Degradation by Proteases
Published in Biophysical journal (31-01-2012)Get full text
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Regulation of proteoglycan and hyaluronan synthesis by elevated level of intracellular cyclic adenosine monophosphate in peritubular cells from immature rat testis
Published in Molecular and cellular biochemistry (01-10-1998)“…The effects of an increase in intracellular cAMP concentration on proteoglycan (PG) synthesis by peritubular (PT) cells from immature rat testis were…”
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In Vitro Synthesis of Proteoglycans and Collagen in Primary Cultures of Mantle Cells from the Nacreous Mollusk, Haliotis tuberculata: A New Model for Study of Molluscan Extracellular Matrix
Published in Marine biotechnology (New York, N.Y.) (01-07-2000)“…In Mollusca, the mantle produces an organic matrix that mineralizes in time to make shell. Primary mantle cell cultures from the nacreous gastropod Haliotis…”
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Involvement of αvβ 3 integrin and disruption of endothelial fibronectin network during the adhesion of the human ovarian adenocarcinoma cell line IGROV1 on the human umbilical vein cell extracellular matrix
Published in International journal of cancer (20-06-2002)“…Like the majority of tumor cells, ovarian cancer cell growth is critically dependent on their neovascularization. Adhesion molecules and cellular events that…”
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Involvement of alphavbeta 3 integrin and disruption of endothelial fibronectin network during the adhesion of the human ovarian adenocarcinoma cell line IGROV1 on the human umbilical vein cell extracellular matrix
Published in International journal of cancer (20-06-2002)“…Like the majority of tumor cells, ovarian cancer cell growth is critically dependent on their neovascularization. Adhesion molecules and cellular events that…”
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Activation of protein kinase C pathway by phorbol ester results in a proteoglycan synthesis increase in peritubular cells from immature rat testis
Published in Biochimica et biophysica acta (04-01-1999)“…In cultured peritubular cells (PT) from rat testis, protein kinase C (PKC) was activated by phorbol 12-myristate 13-acetate (PMA). PMA enhanced the synthesis…”
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IGF-1 stimulates synthesis of undersulfated proteoglycans and of hyaluronic acid by peritubular cells from immature rat testis
Published in Biochimica et biophysica acta (11-09-1997)“…The exposure of confluent peritubular (PT) cells from immature rat testis to insulin-like growth factor-1 (IGF-1) induced a time and dose-dependent increase of…”
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