Search Results - "Thibodeaux, Suzanne R"
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Assessing deviations for HPCs obtained during COVID‐19 (ADHOC): Evaluating impact of the COVID‐19 pandemic on cellular therapy products and processes, the BEST collaborative study
Published in Transfusion (Philadelphia, Pa.) (01-04-2023)“…Background The success of allogeneic hematopoietic stem cell transplantation is dependent on a world‐wide network of collection centers providing donations…”
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B7-H1-dependent sex-related differences in tumor immunity and immunotherapy responses
Published in The Journal of immunology (1950) (01-09-2010)“…CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs) are immunopathogenic in cancers by impeding tumor-specific immunity. B7-homologue 1 (B7-H1) (CD274) is a…”
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Mitigating Age-Related Immune Dysfunction Heightens the Efficacy of Tumor Immunotherapy in Aged Mice
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Although cancer tends to affect the elderly, most preclinical studies are carried out in young subjects. In this study, we developed a melanoma-specific cancer…”
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Commentary on Hemolytic Anemia and Thrombocytopenia: How to Treat?
Published in Clinical chemistry (Baltimore, Md.) (01-06-2020)Get full text
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Updates in Blood Banking and Transfusion Medicine
Published in Clinics in laboratory medicine (01-12-2021)Get full text
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A 54-Year-Old Man with Complicated Blood Bank Antibody Testing
Published in Clinical chemistry (Baltimore, Md.) (01-12-2019)Get full text
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Ensuring safety of the blood supply in the United States: Donor screening, testing, emerging pathogens, and pathogen inactivation
Published in Seminars in hematology (01-10-2019)“…Safety of the blood supply has been a critical aspect of the transfusion medicine field since its inception, including infections that can be passed to a blood…”
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Transfusion support for patients with sickle cell disease
Published in Transfusion and apheresis science (01-10-2022)“…Red blood cell (RBC) transfusion is an essential treatment for many patients with sickle cell disease (SCD), whose RBCs express hemoglobin S (HbS), a mutated…”
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Immunotherapy Using Chimeric Antigen Receptor-Engineered T Cells: A Novel Cellular Therapy with Important Implications for the Clinical Laboratory
Published in Clinical chemistry (Baltimore, Md.) (01-04-2019)“…We have entered a new era of cancer therapy, with a number of immune-based therapies already used clinically as a standard of care. Adoptive cellular…”
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Vascular access for red blood cell exchange
Published in Transfusion (Philadelphia, Pa.) (01-02-2018)“…Red blood cell exchange is the process of removing red blood cells from a patient and replacing them with donated blood using either automated or manual…”
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IFNα Augments Clinical Efficacy of Regulatory T-cell Depletion with Denileukin Diftitox in Ovarian Cancer
Published in Clinical cancer research (01-07-2021)“…Immunotherapy treats some cancers, but not ovarian cancer. Regulatory T cells (Tregs) impede anti-ovarian cancer immunity but effective human Treg-directed…”
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Volume determination methods for hematopoietic progenitor cell products collected by apheresis
Published in Cytotherapy (Oxford, England) (01-11-2021)“…CD34+ cell count of hematopoietic progenitor cell products is often first determined using a product sample, with the final reported cell count obtained by…”
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Hospital red blood cell and platelet supply and utilization from March to December of the first year of the COVID‐19 pandemic: The BEST collaborative study
Published in Transfusion (Philadelphia, Pa.) (01-08-2022)“…Background At the start of the coronavirus disease 2019 (COVID‐19) pandemic, widespread blood shortages were anticipated. We sought to determine how hospital…”
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Considerations for immune effector cell therapy collections: a white paper from the American Society for Apheresis
Published in Cytotherapy (Oxford, England) (01-09-2022)“…This white paper was developed to provide leukapheresis guidance for the collection of mononuclear cells from adult and pediatric patients who are destined for…”
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A multicenter evaluation of heterogeneity in cellular therapy processing laboratory procedure times to assess workload capacity
Published in Transfusion (Philadelphia, Pa.) (01-08-2020)“…BACKGROUND Growth in size and complexity of clinical hematopoietic progenitor cell (HPC) transplant programs necessitates parallel increases in cellular…”
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Lack of defined apheresis collection criteria in publicly available CAR‐T cell clinical trial descriptions: Comprehensive review of over 600 studies
Published in Journal of clinical apheresis (01-06-2022)“…Background Chimeric antigen receptor T (CAR‐T) cell successes have encouraged continued clinical study. Apheresis collection of starting material for CAR‐T…”
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Aged regulatory T cells protect from autoimmune inflammation despite reduced STAT3 activation and decreased constraint of IL‐17 producing T cells
Published in Aging cell (01-06-2012)“…Summary Regulatory T cells (Tregs) are specialized CD4+ T lymphocytes helping defend against autoimmunity and inflammation. Although age is associated with…”
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More efficient exchange of sickle red blood cells can be achieved by exchanging the densest red blood cells: An ex vivo proof of concept study
Published in Transfusion and apheresis science (01-02-2019)“…In sickle cell disease (SCD), red blood cells (RBCs) containing hemoglobin S can be denser than RBCs containing wild-type hemoglobin, especially when…”
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Optimizing management of replacement fluids for therapeutic plasma exchange: Use of an automated mathematical model to predict post‐procedure fibrinogen and antithrombin levels in high‐risk patients
Published in Journal of clinical apheresis (01-01-2020)“…Background Therapeutic plasma exchange (TPE) utilizes an extracorporeal circuit to remove pathologic proteins causing serious illness. When processing a…”
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Novel gene and cellular therapy approaches for treating HIV
Published in Discovery medicine (01-04-2016)“…Advances in HIV drug therapy have drastically decreased mortality and significantly improved quality of life for HIV infected patients since the early days of…”
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