Search Results - "Thiaville, Patrick C."

Novel genomic island modifies DNA with 7-deazaguanine derivatives by Thiaville, Jennifer J., Kellner, Stefanie M., Yuan, Yifeng, Hutinet, Geoffrey, Thiaville, Patrick C., Jumpathong, Watthanachai, Mohapatra, Susovan, Brochier-Armanet, Celine, Letarov, Andrey V., Hillebrand, Roman, Malik, Chanchal K., Rizzo, Carmelo J., Dedon, Peter C., de Crécy-Lagard, Valérie

“…The discovery of ∼20-kb gene clusters containing a family of paralogs of tRNA guanosine transglycosylase genes, called tgtA5, alongside 7-cyano-7-deazaguanine…”
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Essentiality of threonylcarbamoyladenosine (t6A), a universal tRNA modification, in bacteria by Thiaville, Patrick C., El Yacoubi, Basma, Köhrer, Caroline, Thiaville, Jennifer J., Deutsch, Chris, Iwata‐Reuyl, Dirk, Bacusmo, Jo Marie, Armengaud, Jean, Bessho, Yoshitaka, Wetzel, Collin, Cao, Xiaoyu, Limbach, Patrick A., RajBhandary, Uttam L., Crécy‐Lagard, Valérie

“…Summary Threonylcarbamoyladenosine (t6A) is a modified nucleoside universally conserved in tRNAs in all three kingdoms of life. The recently discovered genes…”
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Diversity of the biosynthesis pathway for threonylcarbamoyladenosine (t6A), a universal modification of tRNA by Thiaville, Patrick C, Iwata-Reuyl, Dirk, de Crécy-Lagard, Valérie

“…The tRNA modification field has a rich literature covering biochemical analysis going back more than 40 years, but many of the corresponding genes were only…”
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A genetic investigation of the KEOPS complex in halophilic Archaea by Naor, Adit, Thiaville, Patrick C, Altman-Price, Neta, Cohen-Or, Ifat, Allers, Thorsten, de Crécy-Lagard, Valérie, Gophna, Uri

“…KEOPS is an important cellular complex conserved in Eukarya, with some subunits conserved in Archaea and Bacteria. This complex was recently found to play an…”
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USER Friendly Cloning Coupled with Chitin-Based Natural Transformation Enables Rapid Mutagenesis of Vibrio vulnificus by GULIG, Paul A, TUCKER, Matthew S, THIAVILLE, Patrick C, JOSEPH, Jennifer L, BROWN, Roslyn N

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Cross kingdom functional conservation of the core universally conserved threonylcarbamoyladenosine tRNA synthesis enzymes by Thiaville, Patrick C, El Yacoubi, Basma, Perrochia, Ludovic, Hecker, Arnaud, Prigent, Magali, Thiaville, Jennifer J, Forterre, Patrick, Namy, Olivier, Basta, Tamara, de Crécy-Lagard, Valérie

“…Threonylcarbamoyladenosine (t(6)A) is a universal modification located in the anticodon stem-loop of tRNAs. In yeast, both cytoplasmic and mitochondrial tRNAs…”
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Genotype Is Correlated with but Does Not Predict Virulence of Vibrio vulnificus Biotype 1 in Subcutaneously Inoculated, Iron Dextran-Treated Mice by Thiaville, Patrick C, Bourdage, Keri L, Wright, Anita C, Farrell-Evans, Melissa, Garvan, Cynthia Wilson, Gulig, Paul A

“…Vibrio vulnificus is the leading cause of reported deaths from infections related to consumption of seafood in the United States. Affected predisposed…”
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Global translational impacts of the loss of the tRNA modification t6A in yeast by Thiaville, Patrick, Legendre, Rachel, Rojas-Benitez, Diego, Baudin-Baillieu, Agnes, Hatin, Isabelle, Chalancon, Guilhem, Glavic, Alvaro, Namy, Olivier, de Crecy-Lagard, Valerie

“…The universal tRNA modification t6A is found at position 37 of nearly all tRNAs decoding ANN codons. The absence of t6A37 leads to severe growth defects in…”
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The Levels of a Universally Conserved tRNA Modification Regulate Cell Growth by Rojas-Benitez, Diego, Thiaville, Patrick C., de Crécy-Lagard, Valérie, Glavic, Alvaro

“…N6-Threonylcarbamoyl-adenosine (t6A) is a universal modification occurring at position 37 in nearly all tRNAs that decode A-starting codons, including the…”
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The archaeal COG1901/DUF358 SPOUT-methyltransferase members, together with pseudouridine synthase Pus10, catalyze the formation of 1-methylpseudouridine at position 54 of tRNA by Chatterjee, Kunal, Blaby, Ian K, Thiaville, Patrick C, Majumder, Mrinmoyee, Grosjean, Henri, Yuan, Y Adam, Gupta, Ramesh, de Crécy-Lagard, Valérie

“…The methylation of pseudouridine (Ψ) at position 54 of tRNA, producing m(1)Ψ, is a hallmark of many archaeal species, but the specific methylase involved in…”
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Discovery of the β-barrel-type RNA methyltransferase responsible for N6-methylation of N6-threonylcarbamoyladenosine in tRNAs by Kimura, Satoshi, Miyauchi, Kenjyo, Ikeuchi, Yoshiho, Thiaville, Patrick C, Crécy-Lagard, Valérie de, Suzuki, Tsutomu

“…Methylation is a versatile reaction involved in the synthesis and modification of biologically active molecules, including RNAs. N(6)-methyl-threonylcarbamoyl…”
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The t6A modification acts as a positive determinant for the anticodon nuclease PrrC, and is distinctively nonessential in Streptococcus mutans by Bacusmo, Jo Marie, Orsini, Silvia S., Hu, Jennifer, DeMott, Michael, Thiaville, Patrick C., Elfarash, Ameer, Paulines, Mellie June, Rojas-Benítez, Diego, Meineke, Birthe, Deutsch, Chris, Iwata-Reuyl, Dirk, Limbach, Patrick A., Dedon, Peter C., Rice, Kelly C., Shuman, Stewart, Crécy-Lagard, Valérie de

“…Endoribonuclease toxins (ribotoxins) are produced by bacteria and fungi to respond to stress, eliminate non-self competitor species, or interdict virus…”
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The t 6 A modification acts as a positive determinant for the anticodon nuclease PrrC, and is distinctively nonessential in Streptococcus mutans by Bacusmo, Jo Marie, Orsini, Silvia S, Hu, Jennifer, DeMott, Michael, Thiaville, Patrick C, Elfarash, Ameer, Paulines, Mellie June, Rojas-Benítez, Diego, Meineke, Birthe, Deutsch, Chris, Iwata-Reuyl, Dirk, Limbach, Patrick A, Dedon, Peter C, Rice, Kelly C, Shuman, Stewart, Crécy-Lagard, Valérie de

“…Endoribonuclease toxins (ribotoxins) are produced by bacteria and fungi to respond to stress, eliminate non-self competitor species, or interdict virus…”
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The emerging role of complex modifications of tRNA Lys UUU in signaling pathways by Thiaville, Patrick C, de Crécy-Lagard, Valérie

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The emerging role of complex modifications of tRNALysUUU in signaling pathways by Thiaville, Patrick, de Crecy-Lagard, Valerie

“…Coordination of cell growth with nutrient availability, in particular amino acids, is a central problem that has been solved by the implementation of complex…”
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Use of a marker plasmid to examine differential rates of growth and death between clinical and environmental strains of Vibrio vulnificus in experimentally infected mice by Starks, Angela M., Bourdage, Keri L., Thiaville, Patrick C., Gulig, Paul A.

“…Summary Vibrio vulnificus is Gram‐negative bacterium that contaminates oysters, causing highly lethal sepsis after consumption of raw oysters and wound…”
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Discovery of the β-barrel–type RNA methyltransferase responsible for N 6 -methylation of N 6 -threonylcarbamoyladenosine in tRNAs by Kimura, Satoshi, Miyauchi, Kenjyo, Ikeuchi, Yoshiho, Thiaville, Patrick C., Crécy-Lagard, Valérie de, Suzuki, Tsutomu

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Essentiality of threonylcarbamoyladenosine (t 6 A ), a universal t RNA modification, in bacteria by Thiaville, Patrick C., El Yacoubi, Basma, Köhrer, Caroline, Thiaville, Jennifer J., Deutsch, Chris, Iwata‐Reuyl, Dirk, Bacusmo, Jo Marie, Armengaud, Jean, Bessho, Yoshitaka, Wetzel, Collin, Cao, Xiaoyu, Limbach, Patrick A., RajBhandary, Uttam L., de Crécy‐Lagard, Valérie

“…Threonylcarbamoyladenosine (t 6 A ) is a modified nucleoside universally conserved in t RNA s in all three kingdoms of life. The recently discovered genes for…”
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Global translational impacts of the loss of the tRNA modification t 6 A in yeast by Thiaville, Patrick C, Legendre, Rachel, Rojas-Benítez, Diego, Baudin-Baillieu, Agnès, Hatin, Isabelle, Chalancon, Guilhem, Glavic, Alvaro, Namy, Olivier, de Crécy-Lagard, Valérie

“…The universal tRNA modification t A is found at position 37 of nearly all tRNAs decoding ANN codons. The absence of t A leads to severe growth defects in…”
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