Search Results - "Thi Le Duyen, Huynh"

Combination of inflammatory and vascular markers in the febrile phase of dengue is associated with more severe outcomes by Vuong, Nguyen Lam, Lam, Phung Khanh, Ming, Damien Keng Yen, Duyen, Huynh Thi Le, Nguyen, Nguyet Minh, Tam, Dong Thi Hoai, Duong Thi Hue, Kien, Chau, Nguyen Vv, Chanpheaktra, Ngoun, Lum, Lucy Chai See, Pleités, Ernesto, Simmons, Cameron P, Rosenberger, Kerstin D, Jaenisch, Thomas, Bell, David, Acestor, Nathalie, Halleux, Christine, Olliaro, Piero L, Wills, Bridget A, Geskus, Ronald B, Yacoub, Sophie

“…Early identification of severe dengue patients is important regarding patient management and resource allocation. We investigated the association of 10…”
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Association of Microvascular Function and Endothelial Biomarkers With Clinical Outcome in Dengue: An Observational Study by Yacoub, Sophie, Lam, Phung Khanh, Vu, Le Hoang Mai, Le, Thi Lien, Ha, Ngo Thanh, Toan, Tran Thi, Van, Nguyen Thu, Quyen, Nguyen Than Ha, Duyen, Huynh Thi Le, Van Kinh, Nguyen, Fox, Annette, Mongkolspaya, Juthathip, Wolbers, Marcel, Simmons, Cameron Paul, Screaton, Gavin Robert, Wertheim, Heiman, Wills, Bridget

“…Background. The hallmark of severe dengue is increased microvascular permeability, but alterations in the microcirculation and their evolution over the course…”
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Dengue viremia kinetics and effects on platelet count and clinical outcomes: An analysis of 2340 patients from Vietnam by Vuong, Nguyen Lam, Quyen, Nguyen Than Ha, Tien, Nguyen Thi Hanh, Duong Thi Hue, Kien, Duyen, Huynh Thi Le, Lam, Phung Khanh, Tam, Dong Thi Hoai, Van Ngoc, Tran, Jaenisch, Thomas, Simmons, Cameron P, Yacoub, Sophie, Wills, Bridget A, Geskus, Ronald

“…Viremia is a critical factor in understanding the pathogenesis of dengue infection, but limited data exist on viremia kinetics. This study aimed to investigate…”
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Endothelial Nitric Oxide Pathways in the Pathophysiology of Dengue: A Prospective Observational Study by Yacoub, Sophie, Lam, Phung Khanh, Huynh, Trieu Trung, Ho, Hong Hanh Nguyen, Thi, Hoai Tam Dong, Van, Nguyen Thu, Le Thi Lien, Ha, Quyen Nguyen Than, Le, Duyen Huynh Thi, Mongkolspaya, Juthathip, Culshaw, Abigail, Yeo, Tsin Wen, Wertheim, Heiman, Simmons, Cameron, Screaton, Gavin, Wills, Bridget

“…Dengue can cause increased vascular permeability that may lead to hypovolemic shock. Endothelial dysfunction may underlie this; however, the association of…”
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Timing of CD8+ T cell responses in relation to commencement of capillary leakage in children with dengue by Dung, Nguyen Thi Phuong, Duyen, Huynh Thi Le, Thuy, Nguyen Thi Van, Ngoc, Tran Van, Chau, Nguyen Van Vinh, Hien, Tran Tinh, Rowland-Jones, Sarah L, Dong, Tao, Farrar, Jeremy, Wills, Bridget, Simmons, Cameron P

“…Immune activation is a feature of dengue hemorrhagic fever (DHF) and CD8+ T cell responses in particular have been suggested as having a role in the…”
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Complete human CD1a deficiency on Langerhans cells due to a rare point mutation in the coding sequence by Cerny, Daniela, PhD, Thi Le, Duyen Huynh, MSc, The, Trung Dinh, MD, PhD, Zuest, Roland, PhD, KG, Srinivasan, PhD, Velumani, Sumathy, MSc, Khor, Chiea Chuen, MD, PhD, Mori, Lucia, PhD, Simmons, Cameron P., PhD, Poidinger, Michael, PhD, Zolezzi, Francesca, PhD, Ginhoux, Florent, PhD, Haniffa, Muzlifah, MD, PhD, Wills, Bridget, MD, DM, Fink, Katja, PhD

“…MHC class I molecules present peptides to T cells, whereas CD1 molecules present lipids to natural killer T cells and other CD1-restricted T cells.1 CD1a is…”
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Blockade of dengue virus transmission from viremic blood to Aedes aegypti mosquitoes using human monoclonal antibodies by Tuan Vu, Trung, Clapham, Hannah, Huynh, Van Thi Thuy, Vo Thi, Long, Le Thi, Dui, Vu, Nhu Tuyet, Nguyen, Giang Thi, Huynh, Trang Thi Xuan, Duong, Kien Thi Hue, Tran, Vi Thuy, Huynh, Huy Le Anh, Le Huynh, Duyen Thi, Huynh, Thuy Le Phuong, Nguyen, Thuy Thi Van, Nguyen, Nguyet Minh, Luong, Tai Thi Hue, Phong, Nguyen Thanh, Nguyen, Chau Van Vinh, Gough, Gerald, Wills, Bridget, Carrington, Lauren B, Simmons, Cameron P

“…Dengue is the most prevalent arboviral disease of humans. Virus neutralizing antibodies are likely to be critical for clinical immunity after vaccination or…”
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Dengue virus induces PCSK9 expression to alter antiviral responses and disease outcomes by Gan, Esther Shuyi, Tan, Hwee Cheng, Le, Duyen Huynh Thi, Huynh, Trieu Trung, Wills, Bridget, Seidah, Nabil G, Ooi, Eng Eong, Yacoub, Sophie

“…Dengue virus (DENV) infection requires cholesterol as a proviral factor, although statin treatment did not show antiviral efficacy in patients with dengue…”
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Hyperinflammatory Syndrome, Natural Killer Cell Function, and Genetic Polymorphisms in the Pathogenesis of Severe Dengue by Vuong, Nguyen Lam, Cheung, Ka Wai, Periaswamy, Balamurugan, Vi, Tran Thuy, Duyen, Huynh Thi Le, Leong, Yan Shan, Binte Hamis, Zayanah Noor, Gregorova, Michaela, Ooi, Eng Eong, Sessions, October, Rivino, Laura, Yacoub, Sophie

“…Severe dengue, characterized by shock and organ dysfunction, is driven by an excessive host immune response. We investigated the role of hyperinflammation in…”
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C-reactive protein as a potential biomarker for disease progression in dengue: a multi-country observational study by Vuong, Nguyen Lam, Le Duyen, Huynh Thi, Lam, Phung Khanh, Tam, Dong Thi Hoai, Vinh Chau, Nguyen Van, Van Kinh, Nguyen, Chanpheaktra, Ngoun, Lum, Lucy Chai See, Pleités, Ernesto, Jones, Nick Keith, Simmons, Cameron Paul, Rosenberger, Kerstin, Jaenisch, Thomas, Halleux, Christine, Olliaro, Piero Luigi, Wills, Bridget, Yacoub, Sophie

“…Dengue infection can cause a wide spectrum of clinical outcomes. The severe clinical manifestations occur sufficiently late in the disease course, during day…”
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Using NS1 Flavivirus Protein Microarray to Infer Past Infecting Dengue Virus Serotype and Number of Past Dengue Virus Infections in Vietnamese Individuals by Thao, Tran Thi Nhu, de Bruin, Erwin, Phuong, Huynh Thi, Thao Vy, Nguyen Ha, van den Ham, Henk-Jan, Wills, Bridget A, Tien, Nguyen Thi Hanh, Le Duyen, Huynh Thi, Trung, Dinh The, Whitehead, Stephen S, Boni, Maciej F, Koopmans, Marion, Clapham, Hannah E

“…Abstract Background In recent years, researchers have had an increased focus on multiplex microarray assays, in which antibodies are measured against multiple…”
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Endothelial and inflammatory pathophysiology in dengue shock: New insights from a prospective cohort study in Vietnam by McBride, Angela, Duyen, Huynh Thi Le, Vuong, Nguyen Lam, Tho, Phan Vinh, Tai, Luong Thi Hue, Phong, Nguyen Thanh, Ngoc, Nguyen Thanh, Yen, Lam Minh, Nhat, Phung Tran Huy, Vi, Tran Thuy, Llewelyn, Martin J, Thwaites, Louise, Hao, Nguyen Van, Yacoub, Sophie

“…Dengue shock (DS) is the most severe complication of dengue infection; endothelial hyperpermeability leads to profound plasma leakage, hypovolaemia and…”
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Skin dendritic cell and T cell activation associated with dengue shock syndrome by Duyen, Huynh Thi Le, Cerny, Daniela, Trung, Dinh The, Pang, Jassia, Velumani, Sumathy, Toh, Ying Xiu, Qui, Phan Tu, Hao, Nguyen Van, Simmons, Cameron, Haniffa, Muzlifah, Wills, Bridget, Fink, Katja

“…The pathogenesis of severe dengue remains unclear, particularly the mechanisms underlying the plasma leakage that results in hypovolaemic shock in a small…”
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Visual and Biochemical Evidence of Glycocalyx Disruption in Human Dengue Infection, and Association With Plasma Leakage Severity by Lam, Phung Khanh, McBride, Angela, Le, Duyen Huynh Thi, Huynh, Trieu Trung, Vink, Hans, Wills, Bridget, Yacoub, Sophie

“…Dengue is the most common arboviral infection globally; a minority of patients develop shock due to profound plasma leak through a disrupted endothelial…”
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Households as foci for dengue transmission in highly urban Vietnam by Anders, Katherine L, Nga, Le Hong, Thuy, Nguyen Thi Van, Ngoc, Tran Van, Tam, Cao Thi, Tai, Luong Thi Hue, Truong, Nguyen Thanh, Duyen, Huynh Thi Le, Trung, Vu Tuan, Kien, Duong Thi Hue, Wolbers, Marcel, Wills, Bridget, Chau, Nguyen Van Vinh, Tho, Nguyen Dac, Simmons, Cameron P

“…Dengue control programs commonly employ reactive insecticide spraying around houses of reported cases, with the assumption that most dengue virus (DENV)…”
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Genome evolution of dengue virus serotype 1 under selection by Wolbachia pipientis in Aedes aegypti mosquitoes by Thi Hue Kien, Duong, Edenborough, Kathryn, da Silva Goncalves, Daniela, Thuy Vi, Tran, Casagrande, Etiene, Thi Le Duyen, Huynh, Thi Long, Vo, Thi Dui, Le, Thi Tuyet Nhu, Vu, Thi Giang, Nguyen, Thi Xuan Trang, Huynh, Lee, Elvina, Donovan-Banfield, I’ah, Thi Thuy Van, Huynh, Minh Nguyet, Nguyen, Thanh Phong, Nguyen, Van Vinh Chau, Nguyen, Wills, Bridget, Yacoub, Sophie, Flores, Heather, Simmons, Cameron

“…Abstract The introgression of antiviral strains of Wolbachia into Aedes aegypti mosquito populations is a public health intervention for the control of dengue…”
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Assessment of microalbuminuria for early diagnosis and risk prediction in dengue infections by Hanh Tien, Nguyen Thi, Lam, Phung Khanh, Duyen, Huynh Thi Le, Ngoc, Tran Van, Ha, Phan Thi Thanh, Kieu, Nguyen Tan Thanh, Simmons, Cameron, Wolbers, Marcel, Wills, Bridget

“…Dengue is the most important arboviral infection of humans. Following an initial febrile period, a small proportion of infected patients develop a…”
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Metformin as adjunctive therapy for dengue in overweight and obese patients: a protocol for an open-label clinical trial (MeDO) by Nguyen, Nguyet Minh, Chanh, Ho Quang, Tam, Dong Thi Hoai, Vuong, Nguyen Lam, Chau, Nguyen Thi Xuan, Chau, Nguyen Van Vinh, Phong, Nguyen Thanh, Trieu, Huynh Trung, Luong Thi Hue, Tai, Cao Thi, Tam, Dinh The, Trung, Duyen, Huynh Thi Le, Van, Ninh Thi Thanh, Nguyen Than Ha, Quyen, Rivino, Laura, Gallagher, Peter, Jones, Nick K, Geskus, Ronald B, Kestelyn, Evelyne, Yacoub, Sophie

“… Dengue is a disease of major global importance. While most symptomatic infections are mild, a small proportion of patients progress to severe disease with…”
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Metformin as adjunctive therapy for dengue in overweight and obese patients: a protocol for an open-label clinical trial (MeDO) by Nguyen, Nguyet Minh, Chanh, Ho Quang, Tam, Dong Thi Hoai, Vuong, Nguyen Lam, Chau, Nguyen Thi Xuan, Chau, Nguyen Van Vinh, Phong, Nguyen Thanh, Trieu, Huynh Trung, Luong Thi Hue, Tai, Cao Thi, Tam, Dinh The, Trung, Duyen, Huynh Thi Le, Van, Ninh Thi Thanh, Nguyen Than Ha, Quyen, Rivino, Laura, Gallagher, Peter, Jones, Nick K., Geskus, Ronald B., Kestelyn, Evelyne, Yacoub, Sophie

“…Background:  Dengue is a disease of major global importance. While most symptomatic infections are mild, a small proportion of patients progress to severe…”
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Dengue viremia kinetics and effects on platelet count and clinical outcomes: An analysis of 2340 patients from Vietnam by Vuong, Nguyen Lam, Quyen, Nguyen Than Ha, Tien, Nguyen Thi Hanh, Duong Thi Hue, Kien, Duyen, Huynh Thi Le, Lam, Phung Khanh, Tam, Dong Thi Hoai, Van Ngoc, Tran, Jaenisch, Thomas, Simmons, Cameron P, Yacoub, Sophie, Wills, Bridget A, Geskus, Ronald

“…Background: Viremia is a critical factor in understanding the pathogenesis of dengue infection, but limited data exist on viremia kinetics. This study aimed to…”
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