Search Results - "Thi Kim Oanh, Dao"

Novel isatin-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents by Nam, Nguyen-Hai, Huong, Tran Lan, Mai Dung, Do Thi, Phuong Dung, Phan Thi, Kim Oanh, Dao Thi, Quyen, Do, Thao, Le Thi, Park, Sang Ho, Kim, Kyung Rok, Han, Byung Woo, Yun, Jieun, Kang, Jong Soon, Kim, Youngsoo, Han, Sang-Bae

“…Accumulated clinical studies have demonstrated that histone deacetylase (HDAC) inhibitors show great potential for the treatment of cancer. SAHA (Vorinostat,…”
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Novel (E)‐3‐(3‐Oxo‐4‐substituted‐3,4‐dihydro‐2H‐benzo[b][1,4]oxazin‐6‐yl)‐N‐hydroxypropenamides as Histone Deacetylase Inhibitors: Design, Synthesis and Bioevaluation by Minh Sang, Doan, Ho Na, Ik, Tien Anh, Duong, Thi Mai Dung, Do, Thi Thu Hang, Nguyen, Phuong‐Anh, Nguyen T., Hai, Pham‐The, Thi Kim Oanh, Dao, Thanh Tung, Truong, Jung Lee, Soo, Hee Kwon, Joo, Soon Kang, Jong, Han, Sang‐Bae, Thi Thanh Hai, Dinh, Nam, Nguyen‐Hai

“…Herein, we report the design, synthesis and evaluation of novel (E)‐3‐(3‐oxo‐4‐substituted‐3,4‐dihydro‐2H‐benzo[b][1,4]oxazin‐6‐yl)‐N‐hydroxypropenamides (4…”
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New benzothiazole/thiazole-containing hydroxamic acids as potent histone deacetylase inhibitors and antitumor agents by Tung, Truong Thanh, Oanh, Dao Thi Kim, Dung, Phan Thi Phuong, Hue, Van Thi My, Park, Sang Ho, Han, Byung Woo, Kim, Youngsoo, Hong, Jin-Tae, Han, Sang-Bae, Nam, Nguyen-Hai

“…Results from clinical studies have demonstrated that inhibitors of histone deacetylase (HDAC) enzymes possess promise for the treatment of several types of…”
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Novel 3,4-dihydro-4-oxoquinazoline-based acetohydrazides: Design, synthesis and evaluation of antitumor cytotoxicity and caspase activation activity by Huan, Le Cong, Tran, Phuong-Thao, Phuong, Cao Viet, Duc, Phan Huy, Anh, Duong Tien, Hai, Pham The, Huong, Le Thi Thu, Thuan, Nguyen Thi, Lee, Hye Jin, Park, Eun Jae, Kang, Jong Soon, Linh, Nguyen Phuong, Hieu, Tran Trung, Oanh, Dao Thi Kim, Han, Sang-Bae, Nam, Nguyen-Hai

“…[Display omitted] •Novel (E)-N′-benzylidene-2-(4-oxoquinazolin-3(4H)-yl)acetohydrazides were synthesized.•The acetohydrazides 5a-i exhibited potent…”
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Benzothiazole-containing hydroxamic acids as histone deacetylase inhibitors and antitumor agents by Oanh, Dao Thi Kim, Hai, Hoang Van, Park, Sang Ho, Kim, Hyun-Jung, Han, Byung-Woo, Kim, Hyung-Sook, Hong, Jin-Tae, Han, Sang-Bae, Hue, Van Thi My, Nam, Nguyen-Hai

“…Data from clinical studies indicate that inhibitors of Class I and Class II histone deacetylase (HDAC) enzymes show great promise for the treatment of cancer…”
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Synthesis, bioevaluation and docking study of 5-substitutedphenyl-1,3,4-thiadiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents by Nam, Nguyen-Hai, Huong, Tran Lan, Dung, Do Thi Mai, Dung, Phan Thi Phuong, Oanh, Dao Thi Kim, Park, Sang Ho, Kim, Kyungrok, Han, Byung Woo, Yun, Jieun, Kang, Jong Soon, Kim, Youngsoo, Han, Sang-Bae

“…Since the first histone deacetylase (HDAC) inhibitor (Zolinza®, widely known as suberoylanilide hydroxamic acid; SAHA) was approved by the Food and Drug…”
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New Acetohydrazides Incorporating 2‐Oxoindoline and 4‐Oxoquinazoline: Synthesis and Evaluation of Cytotoxicity and Caspase Activation Activity by Huan, Le Cong, Anh, Duong Tien, Truong, Bui Xuan, Duc, Phan Huy, Hai, Pham‐The, Duc‐Anh, Lai, Huong, Le‐Thi‐Thu, Park, Eun Jae, Lee, Hye Jin, Kang, Jong Soon, Tran, Phuong‐Thao, Thanh Hai, Dinh Thi, Kim Oanh, Dao Thi, Han, Sang‐Bae, Nam, Nguyen‐Hai

“…In our search for new small molecules activating procaspase‐3, we have designed and synthesized a series of new acetohydrazides incorporating both…”
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Design, synthesis, and evaluation of novel N'-substituted-1-(4-chlorobenzyl)-1H-indol-3-carbohydrazides as antitumor agents by Huan, Le Cong, Anh, Duong Tien, Hai, Pham-The, Anh, Lai Duc, Park, Eun Jae, Ji, A Young, Kang, Jong Soon, Dung, Do Thi Mai, Oanh, Dao Thi Kim, Tung, Truong Thanh, Hai, Dinh Thi Thanh, Han, Sang-Bae, Nam, Nguyen-Hai

“…In continuity of our search for novel anticancer agents acting as procaspase activators, we have designed and synthesised two series of…”
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Exploration of novel 5′(7′)-substituted-2′-oxospiro[1,3]dioxolane-2,3′-indoline-based N-hydroxypropenamides as histone deacetylase inhibitors and antitumor agents by Dung, Do Thi Mai, Dung, Phan Thi Phuong, Oanh, Dao Thi Kim, Vu, Tran Khac, Hahn, Hyunggu, Han, Byung Woo, Pyo, Minji, Kim, Young Guk, Han, Sang-Bae, Nam, Nguyen-Hai

“…A series of novel 5′(7′)-substituted-2′-oxospiro[1,3]dioxolane-2,3′-indoline-based N-hydroxypropenamides were designed, synthesized and evaluated for histone…”
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Exploration of some indole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents by Huong, Tran Thi Lan, Van Cuong, Le, Huong, Pham Thu, Thao, Tran Phuong, Huong, Le-Thi-Thu, Dung, Phan Thi Phuong, Oanh, Dao Thi Kim, Huong, Nguyen Thi Mai, Quan, Hoang-Van, Vu, Tran Khac, Kim, Jisung, Lee, Jae-Hee, Han, Sang-Bae, Hai, Pham-The, Nam, Nguyen-Hai

“…In our search for novel small molecules targeting histone deacetylases, we have designed and synthesized a series of novel hydroxamic acids incorporating…”
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5-aryl-1,3,4-thiadiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents: synthesis, bioevaluation and docking study by Huong, Tran Thi Lan, Dung, Do Thi Mai, Oanh, Dao Thi Kim, Lan, Tran Thi Bich, Dung, Phan Thi Phuong, Loi, Vu Duc, Kim, Kyung Rok, Han, Byung Woo, Yun, Jieun, Kang, Jong Soon, Kim, Youngsoo, Han, Sang-Bae, Nam, Nguyen-Hai

“…The search for newer histone deacetylase (HDAC) inhibitors has attracted a great deal of interest of medicinal chemists worldwide, especially after the first…”
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Design, synthesis, and evaluation of novel N' -substituted-1-(4-chlorobenzyl)-1 H -indol-3-carbohydrazides as antitumor agents by Huan, Le Cong, Anh, Duong Tien, Hai, Pham-The, Anh, Lai Duc, Park, Eun Jae, Ji, A Young, Kang, Jong Soon, Dung, Do Thi Mai, Oanh, Dao Thi Kim, Tung, Truong Thanh, Hai, Dinh Thi Thanh, Han, Sang-Bae, Nam, Nguyen-Hai

“…In continuity of our search for novel anticancer agents acting as procaspase activators, we have designed and synthesised two series of ( )- '…”
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Exploration of novel 5′(7′)-substituted-2 by Do Thi Mai Dung, Phan Thi Phuong Dung, Dao Thi Kim Oanh, Tran Khac Vu, Hyunggu Hahn, Byung Woo Han, Minji Pyo, Young Guk Kim, Sang-Bae Han, Nguyen-Hai Nam

“…A series of novel 5′(7′)-substituted-2′-oxospiro[1,3]dioxolane-2,3′-indoline-based N-hydroxypropenamides were designed, synthesized and evaluated for histone…”
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